SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4jdz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EPB_B_9CRB165_1
(EPIDIDYMAL RETINOIC
ACID-BINDING PROTEIN)		 4jdz SER-ASP RICH
FIBRINOGEN/BONE
SIALOPROTEIN-BINDING
PROTEIN SDRD
(Staphylococcus
aureus) 		5 / 12 PHE A 284
ILE A 272
LEU A 268
ALA A 320
ILE A 329
 None
 0.93A 1epbB-4jdzA:
undetectable		 1epbB-4jdzA:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICT_D_T44D129_1
(TRANSTHYRETIN)		 4jdz SER-ASP RICH
FIBRINOGEN/BONE
SIALOPROTEIN-BINDING
PROTEIN SDRD
(Staphylococcus
aureus) 		4 / 6 LEU A 433
ALA A 530
LEU A 532
THR A 542
 None
 0.75A 1ictB-4jdzA:
8.0		 1ictB-4jdzA:
14.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QHS_A_CLMA999_0
(PROTEIN
(CHLORAMPHENICOL
PHOSPHOTRANSFERASE))		 4jdz SER-ASP RICH
FIBRINOGEN/BONE
SIALOPROTEIN-BINDING
PROTEIN SDRD
(Staphylococcus
aureus) 		5 / 12 VAL A 274
ILE A 272
ILE A 308
ILE A 317
VAL A 278
 None
 1.02A 1qhsA-4jdzA:
undetectable		 1qhsA-4jdzA:
16.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OA1_B_ADNB2005_1
(TRYPTOPHAN
HALOGENASE)		 4jdz SER-ASP RICH
FIBRINOGEN/BONE
SIALOPROTEIN-BINDING
PROTEIN SDRD
(Staphylococcus
aureus) 		4 / 7 GLY A 609
GLY A 608
ASP A 665
LEU A 611
 None
None
CA  A 702 (-2.3A)
None
 0.82A 2oa1B-4jdzA:
undetectable		 2oa1B-4jdzA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VE3_A_REAA1445_1
(PUTATIVE CYTOCHROME
P450 120)		 4jdz SER-ASP RICH
FIBRINOGEN/BONE
SIALOPROTEIN-BINDING
PROTEIN SDRD
(Staphylococcus
aureus) 		5 / 12 ALA A 406
THR A 519
VAL A 446
GLY A 447
GLN A 528
 None
 0.88A 2ve3A-4jdzA:
undetectable		 2ve3A-4jdzA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VE3_B_REAB1445_1
(PUTATIVE CYTOCHROME
P450 120)		 4jdz SER-ASP RICH
FIBRINOGEN/BONE
SIALOPROTEIN-BINDING
PROTEIN SDRD
(Staphylococcus
aureus) 		5 / 12 ALA A 406
THR A 519
VAL A 446
GLY A 447
GLN A 528
 None
 0.89A 2ve3B-4jdzA:
undetectable		 2ve3B-4jdzA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CB8_A_SAMA501_0
(PYRUVATE
FORMATE-LYASE
1-ACTIVATING ENZYME)		 4jdz SER-ASP RICH
FIBRINOGEN/BONE
SIALOPROTEIN-BINDING
PROTEIN SDRD
(Staphylococcus
aureus) 		5 / 12 ASN A 661
GLU A 315
ASP A 665
ASN A 313
VAL A 588
 None
None
CA  A 702 (-2.3A)
None
None
 1.30A 3cb8A-4jdzA:
undetectable		 3cb8A-4jdzA:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_A_CHDA151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 4jdz SER-ASP RICH
FIBRINOGEN/BONE
SIALOPROTEIN-BINDING
PROTEIN SDRD
(Staphylococcus
aureus) 		4 / 7 ILE A 668
GLY A 582
TYR A 610
VAL A 588
 None
 0.86A 3elzA-4jdzA:
undetectable		 3elzA-4jdzA:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KW2_B_ADNB300_1
(PROBABLE R-RNA
METHYLTRANSFERASE)		 4jdz SER-ASP RICH
FIBRINOGEN/BONE
SIALOPROTEIN-BINDING
PROTEIN SDRD
(Staphylococcus
aureus) 		5 / 11 ILE A 395
GLY A 396
LEU A 433
THR A 542
ALA A 530
 None
 1.24A 3kw2B-4jdzA:
undetectable		 3kw2B-4jdzA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNE_G_ACTG601_0
(CHOLINE OXIDASE)		 4jdz SER-ASP RICH
FIBRINOGEN/BONE
SIALOPROTEIN-BINDING
PROTEIN SDRD
(Staphylococcus
aureus) 		4 / 6 ALA A 253
ILE A 254
VAL A 260
ASN A 256
 None
CA  A 701 (-4.2A)
None
CA  A 701 (-2.9A)
 1.10A 3nneG-4jdzA:
undetectable		 3nneG-4jdzA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOU_A_C04A207_1
(UNCHARACTERIZED
PROTEIN)		 4jdz SER-ASP RICH
FIBRINOGEN/BONE
SIALOPROTEIN-BINDING
PROTEIN SDRD
(Staphylococcus
aureus) 		3 / 3 GLY A 296
GLU A 401
THR A 402
 None
 0.49A 4kouA-4jdzA:
undetectable		 4kouA-4jdzA:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OJB_A_198A1001_2
(ANDROGEN RECEPTOR)		 4jdz SER-ASP RICH
FIBRINOGEN/BONE
SIALOPROTEIN-BINDING
PROTEIN SDRD
(Staphylococcus
aureus) 		4 / 7 LEU A 328
ILE A 302
ILE A 305
VAL A 294
 None
 0.86A 4ojbA-4jdzA:
undetectable		 4ojbA-4jdzA:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OU1_A_BEZA302_0
(RETRO-ALDOLASE,
DESIGN RA114)		 4jdz SER-ASP RICH
FIBRINOGEN/BONE
SIALOPROTEIN-BINDING
PROTEIN SDRD
(Staphylococcus
aureus) 		4 / 8 TYR A 349
ILE A 286
ILE A 329
ALA A 320
 None
 0.91A 4ou1A-4jdzA:
undetectable		 4ou1A-4jdzA:
19.96