SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4je1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VM1_A_TAZA504_1
(BETA-LACTAMASE SHV-1)		 4je1 PROBABLE THIOL
PEROXIDASE
(Burkholderia
cenocepacia) 		3 / 3 ASP A 160
TYR A 159
GLU A 148
 None
 0.66A 1vm1A-4je1A:
undetectable		 1vm1A-4je1A:
26.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_C_CTXC1383_1
(CES1 PROTEIN)		 4je1 PROBABLE THIOL
PEROXIDASE
(Burkholderia
cenocepacia) 		4 / 5 PRO A 126
LEU A   6
GLY A   8
LYS A 154
 None
 1.40A 1ya4C-4je1A:
undetectable		 1ya4C-4je1A:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BSZ_E_RTLE177_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 4je1 PROBABLE THIOL
PEROXIDASE
(Burkholderia
cenocepacia) 		5 / 11 LEU A  49
ALA A  25
ALA A  24
VAL A  48
PHE A 114
 None
 1.19A 3bszE-4je1A:
undetectable		 3bszE-4je1A:
23.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ME6_C_CGEC501_1
(CYTOCHROME P450 2B4)		 4je1 PROBABLE THIOL
PEROXIDASE
(Burkholderia
cenocepacia) 		5 / 9 VAL A  82
ILE A  80
PHE A  27
ALA A  25
VAL A 136
 None
 1.17A 3me6C-4je1A:
undetectable		 3me6C-4je1A:
16.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P65_K_IPHK101_0
(INSULIN)		 4je1 PROBABLE THIOL
PEROXIDASE
(Burkholderia
cenocepacia) 		5 / 12 LEU A  39
VAL A  82
ILE A  80
LEU A 138
ALA A  24
 None
 0.96A 4p65F-4je1A:
undetectable
4p65H-4je1A:
undetectable
4p65K-4je1A:
undetectable
4p65L-4je1A:
undetectable		 4p65F-4je1A:
15.15
4p65H-4je1A:
15.15
4p65K-4je1A:
9.03
4p65L-4je1A:
15.15