SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4jel'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NV4_A_ACTA148_0
(UPF0066 PROTEIN
AF_0241)		 4jel CMP/HYDROXYMETHYL
CMP HYDROLASE
(Streptomyces
rimofaciens) 		3 / 3 VAL A 137
GLU A 132
GLU A 138
 None
 0.69A 2nv4A-4jelA:
undetectable		 2nv4A-4jelA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V2G_A_BEZA1222_0
(PEROXIREDOXIN 6)		 4jel CMP/HYDROXYMETHYL
CMP HYDROLASE
(Streptomyces
rimofaciens) 		4 / 7 THR A  54
VAL A  16
SER A  15
GLU A  81
 None
 1.05A 2v2gA-4jelA:
undetectable
2v2gB-4jelA:
undetectable		 2v2gA-4jelA:
22.58
2v2gB-4jelA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V2G_C_BEZC1222_0
(PEROXIREDOXIN 6)		 4jel CMP/HYDROXYMETHYL
CMP HYDROLASE
(Streptomyces
rimofaciens) 		4 / 7 THR A  54
VAL A  16
SER A  15
GLU A  81
 None
 1.07A 2v2gC-4jelA:
undetectable
2v2gD-4jelA:
undetectable		 2v2gC-4jelA:
22.58
2v2gD-4jelA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XP6_A_B40A601_1
(TRANSPORTER)		 4jel CMP/HYDROXYMETHYL
CMP HYDROLASE
(Streptomyces
rimofaciens) 		4 / 5 VAL A  87
ASP A  86
PHE A  48
GLY A  14
 None
 1.25A 4xp6A-4jelA:
undetectable		 4xp6A-4jelA:
16.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_C_EU7C101_0
(MATRIX PROTEIN 2)		 4jel CMP/HYDROXYMETHYL
CMP HYDROLASE
(Streptomyces
rimofaciens) 		5 / 9 ALA A  12
VAL A 156
ALA A 157
VAL A  87
GLY A 161
 None
 1.13A 6bklA-4jelA:
undetectable
6bklB-4jelA:
undetectable
6bklC-4jelA:
undetectable
6bklD-4jelA:
undetectable		 6bklA-4jelA:
10.23
6bklB-4jelA:
10.23
6bklC-4jelA:
10.23
6bklD-4jelA:
10.23