SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4jen'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JTX_A_CVIA200_0
(HYPOTHETICAL
TRANSCRIPTIONAL
REGULATOR IN QACA
5'REGION)		 4jen CMP N-GLYCOSIDASE
(Clostridium
botulinum) 		5 / 12 ILE A 130
ILE A 131
TYR A 132
ILE A  30
ALA A   9
 None
 1.17A 1jtxA-4jenA:
undetectable		 1jtxA-4jenA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QU2_A_MRCA1993_2
(ISOLEUCYL-TRNA
SYNTHETASE)		 4jen CMP N-GLYCOSIDASE
(Clostridium
botulinum) 		3 / 3 GLU A  92
TRP A  95
LYS A 141
 None
 1.32A 1qu2A-4jenA:
undetectable		 1qu2A-4jenA:
12.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2W_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 4jen CMP N-GLYCOSIDASE
(Clostridium
botulinum) 		5 / 12 LEU A  76
VAL A   5
LEU A  37
VAL A  44
LEU A  33
 None
 0.93A 4m2wA-4jenA:
undetectable		 4m2wA-4jenA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q5M_A_ROCA1101_1
(PROTEASE)		 4jen CMP N-GLYCOSIDASE
(Clostridium
botulinum) 		5 / 12 ASP A  45
ILE A  71
ILE A 104
THR A  89
ILE A 130
 None
 0.96A 4q5mA-4jenA:
undetectable		 4q5mA-4jenA:
21.76