SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4jeu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBM_B_RTLB951_2
(PROTEIN (CARTILAGE
OLIGOMERIC MATRIX
PROTEIN))		 4jeu SYNTAXIN-BINDING
PROTEIN 1
(Rattus
norvegicus) 		4 / 4 THR A 361
LEU A 365
VAL A 368
LEU A 372
 None
 0.82A 1fbmD-4jeuA:
undetectable		 1fbmD-4jeuA:
9.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_A_ACTA1869_0
(FPRA)		 4jeu SYNTAXIN-BINDING
PROTEIN 1
(Rattus
norvegicus) 		4 / 4 ASP A 403
HIS A 245
ARG A 406
GLU A 369
 None
 1.27A 1lqtA-4jeuA:
undetectable		 1lqtA-4jeuA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_B_ACTB1430_0
(FPRA)		 4jeu SYNTAXIN-BINDING
PROTEIN 1
(Rattus
norvegicus) 		3 / 3 ASP A 284
ASP A 286
LYS A 339
 None
 1.16A 1lquB-4jeuA:
undetectable		 1lquB-4jeuA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_A_PNXA1435_1
(CHITINASE)		 4jeu SYNTAXIN-BINDING
PROTEIN 1
(Rattus
norvegicus) 		4 / 6 TYR A 499
GLY A 544
SER A 569
ARG A 235
 None
 1.20A 2a3cA-4jeuA:
2.3		 2a3cA-4jeuA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_B_PNXB2434_1
(CHITINASE)		 4jeu SYNTAXIN-BINDING
PROTEIN 1
(Rattus
norvegicus) 		4 / 6 TYR A 499
GLY A 544
SER A 569
ARG A 235
 None
 1.10A 2a3cB-4jeuA:
2.4		 2a3cB-4jeuA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AB2_B_SNLB503_2
(MINERALOCORTICOID
RECEPTOR)		 4jeu SYNTAXIN-BINDING
PROTEIN 1
(Rattus
norvegicus) 		4 / 5 LEU A 287
LEU A 291
LEU A 350
LEU A 348
 None
 1.00A 2ab2B-4jeuA:
undetectable		 2ab2B-4jeuA:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9C_C_ACTC1120_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 4jeu SYNTAXIN-BINDING
PROTEIN 1
SYNTAXIN-1A
(Rattus
norvegicus;
Rattus
norvegicus) 		3 / 3 LYS A  98
TYR B 243
PRO A  67
 None
 1.36A 2j9cC-4jeuA:
undetectable		 2j9cC-4jeuA:
13.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q72_A_IXXA801_1
(TRANSPORTER)		 4jeu SYNTAXIN-BINDING
PROTEIN 1
(Rattus
norvegicus) 		5 / 11 ARG A  65
VAL A  30
ILE A  77
ALA A  73
ASP A  90
 None
 1.13A 2q72A-4jeuA:
2.4		 2q72A-4jeuA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QB4_A_DSMA801_1
(TRANSPORTER)		 4jeu SYNTAXIN-BINDING
PROTEIN 1
(Rattus
norvegicus) 		5 / 12 ARG A  65
VAL A  30
ILE A  77
ALA A  73
ASP A  90
 None
 1.14A 2qb4A-4jeuA:
undetectable		 2qb4A-4jeuA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QM9_B_TDZB202_1
(FATTY ACID-BINDING
PROTEIN, ADIPOCYTE)		 4jeu SYNTAXIN-BINDING
PROTEIN 1
(Rattus
norvegicus) 		5 / 12 TYR A 145
VAL A 545
THR A 557
ALA A 553
ILE A 538
 None
 1.41A 2qm9B-4jeuA:
undetectable		 2qm9B-4jeuA:
14.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BXO_A_SAMA238_1
(N,N-DIMETHYLTRANSFER
ASE)		 4jeu SYNTAXIN-BINDING
PROTEIN 1
(Rattus
norvegicus) 		3 / 3 TYR A 473
GLU A 302
ASP A 309
 None
 0.80A 3bxoA-4jeuA:
3.7		 3bxoA-4jeuA:
18.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BXO_B_SAMB238_1
(N,N-DIMETHYLTRANSFER
ASE)		 4jeu SYNTAXIN-BINDING
PROTEIN 1
(Rattus
norvegicus) 		3 / 3 TYR A 473
GLU A 302
ASP A 309
 None
 0.81A 3bxoB-4jeuA:
3.9		 3bxoB-4jeuA:
18.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CYX_A_ROCA201_2
(HIV-1 PROTEASE)		 4jeu SYNTAXIN-BINDING
PROTEIN 1
(Rattus
norvegicus) 		3 / 3 ARG A 532
VAL A 565
THR A 557
 None
 0.87A 3cyxA-4jeuA:
undetectable		 3cyxA-4jeuA:
11.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H5G_C_LEIC16_0
(COIL SER L16D-PEN)		 4jeu SYNTAXIN-BINDING
PROTEIN 1
(Rattus
norvegicus) 		4 / 6 LEU A 204
LYS A 165
LEU A 169
GLU A 170
 None
 0.84A 3h5gB-4jeuA:
undetectable
3h5gC-4jeuA:
undetectable		 3h5gB-4jeuA:
7.55
3h5gC-4jeuA:
7.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OF4_B_ACTB313_0
(NITROREDUCTASE)		 4jeu SYNTAXIN-BINDING
PROTEIN 1
(Rattus
norvegicus) 		3 / 3 ALA A 188
VAL A 189
GLN A 206
 None
 0.60A 3of4B-4jeuA:
undetectable		 3of4B-4jeuA:
16.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TF1_A_ACTA191_0
(METHYL-ACCEPTING
CHEMOTAXIS PROTEIN)		 4jeu SYNTAXIN-BINDING
PROTEIN 1
SYNTAXIN-1A
(Rattus
norvegicus;
Rattus
norvegicus) 		4 / 5 THR A  56
ILE B 115
PHE B  34
LEU A  71
 None
 1.33A 3tf1A-4jeuA:
undetectable		 3tf1A-4jeuA:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_J_KANJ301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4jeu SYNTAXIN-1A
SYNTAXIN-BINDING
PROTEIN 1
(Rattus
norvegicus) 		4 / 6 ASP A 282
ASP A  49
ASP B 231
GLU B 228
 None
 1.24A 4gkhJ-4jeuA:
undetectable		 4gkhJ-4jeuA:
17.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L78_A_ACTA1327_0
(PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
SYNTHASE)		 4jeu SYNTAXIN-BINDING
PROTEIN 1
(Rattus
norvegicus) 		4 / 4 VAL A 451
THR A 419
GLU A 420
GLU A 421
 None
 1.08A 4l78A-4jeuA:
undetectable		 4l78A-4jeuA:
17.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNW_A_T3A501_2
(THYROID HORMONE
RECEPTOR ALPHA)		 4jeu SYNTAXIN-1A
(Rattus
norvegicus) 		3 / 3 ILE B  44
MET B 219
ARG B  90
 None
 0.81A 4lnwA-4jeuB:
undetectable		 4lnwA-4jeuB:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNX_A_T3A502_2
(THYROID HORMONE
RECEPTOR ALPHA)		 4jeu SYNTAXIN-1A
(Rattus
norvegicus) 		3 / 3 ILE B  44
MET B 219
ARG B  90
 None
 0.83A 4lnxA-4jeuB:
undetectable		 4lnxA-4jeuB:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJ8_B_SPMB201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 4jeu SYNTAXIN-1A
SYNTAXIN-BINDING
PROTEIN 1
(Rattus
norvegicus) 		4 / 8 ASN B 236
MET A  47
GLU B 238
ARG A  39
 None
 1.14A 4mj8B-4jeuB:
undetectable
4mj8C-4jeuB:
undetectable		 4mj8B-4jeuB:
20.33
4mj8C-4jeuB:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4URO_A_NOVA2000_1
(DNA GYRASE SUBUNIT B)		 4jeu SYNTAXIN-BINDING
PROTEIN 1
(Rattus
norvegicus) 		5 / 12 ASN A 548
GLU A 555
ILE A 482
ASP A 488
SER A 241
 None
 1.38A 4uroA-4jeuA:
undetectable		 4uroA-4jeuA:
17.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4URO_B_NOVB2000_1
(DNA GYRASE SUBUNIT B)		 4jeu SYNTAXIN-BINDING
PROTEIN 1
(Rattus
norvegicus) 		5 / 12 ASN A 548
GLU A 555
ILE A 482
ASP A 488
SER A 241
 None
 1.35A 4uroB-4jeuA:
undetectable		 4uroB-4jeuA:
17.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5Q_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 4jeu SYNTAXIN-BINDING
PROTEIN 1
(Rattus
norvegicus) 		4 / 6 ASP A 108
ALA A 173
LYS A 208
THR A 178
 None
 1.27A 4w5qA-4jeuA:
2.4		 4w5qA-4jeuA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4I_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 4jeu SYNTAXIN-BINDING
PROTEIN 1
(Rattus
norvegicus) 		4 / 6 ASP A 108
ALA A 173
LYS A 208
THR A 178
 None
 1.30A 4z4iA-4jeuA:
2.8		 4z4iA-4jeuA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_A_SORA1344_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 4jeu SYNTAXIN-BINDING
PROTEIN 1
(Rattus
norvegicus) 		4 / 5 GLU A 487
LYS A 465
ASP A 488
GLU A 491
 None
 1.42A 5a06A-4jeuA:
3.9		 5a06A-4jeuA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JCN_A_ASCA502_0
(OS09G0567300 PROTEIN)		 4jeu SYNTAXIN-BINDING
PROTEIN 1
(Rattus
norvegicus) 		4 / 5 GLU A 246
PRO A 480
ARG A 551
ARG A 467
 None
 1.43A 5jcnA-4jeuA:
0.0		 5jcnA-4jeuA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L8O_B_CHDB1001_0
(GASTROTROPIN)		 4jeu SYNTAXIN-BINDING
PROTEIN 1
(Rattus
norvegicus) 		5 / 12 PHE A 413
LEU A 573
VAL A 243
SER A 546
GLU A 549
 None
 1.34A 5l8oB-4jeuA:
undetectable		 5l8oB-4jeuA:
11.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUI_B_CTCB405_1
(TETRACYCLINE
DESTRUCTASE TET(50))		 4jeu SYNTAXIN-BINDING
PROTEIN 1
(Rattus
norvegicus) 		4 / 5 ASP A 148
ARG A  39
LEU A 547
MET A 550
 None
 1.25A 5tuiB-4jeuA:
undetectable		 5tuiB-4jeuA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA305_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 4jeu SYNTAXIN-BINDING
PROTEIN 1
(Rattus
norvegicus) 		3 / 3 THR A 441
MET A 443
HIS A 445
 None
 0.87A 5uunA-4jeuA:
undetectable		 5uunA-4jeuA:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AZ3_1_PAR11803_1
(RRNA ALPHA
RIBOSOMAL PROTEIN
EL18)		 4jeu SYNTAXIN-BINDING
PROTEIN 1
(Rattus
norvegicus) 		3 / 3 SER A  83
LYS A  82
SER A  80
 None
 0.44A 6az3P-4jeuA:
undetectable		 6az3P-4jeuA:
10.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_B_ADNB503_0
(ADENOSYLHOMOCYSTEINA
SE)		 4jeu SYNTAXIN-BINDING
PROTEIN 1
(Rattus
norvegicus) 		3 / 3 LEU A 547
GLN A 250
LYS A 577
 None
 0.95A 6exiA-4jeuA:
3.5		 6exiA-4jeuA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F7L_B_ACTB505_0
(AMINE OXIDASE LKCE)		 4jeu SYNTAXIN-BINDING
PROTEIN 1
(Rattus
norvegicus) 		3 / 3 HIS A 445
ASN A 442
LEU A 582
 None
 0.90A 6f7lB-4jeuA:
undetectable		 6f7lB-4jeuA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBV_D_FI8D1904_1
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA')		 4jeu SYNTAXIN-BINDING
PROTEIN 1
(Rattus
norvegicus) 		4 / 8 GLU A 564
VAL A   9
ARG A 292
GLN A 250
 None
 1.28A 6fbvD-4jeuA:
undetectable		 6fbvD-4jeuA:
19.01