SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4jf8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJF_B_ADNB2002_1
(235AA LONG
HYPOTHETICAL
BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)		 4jf8 TRWG COMPONENT OF
TYPE IV SECRETION
SYSTEM
(Bartonella
birtlesii) 		4 / 6 GLU A  95
ASN A 166
PRO A 165
ALA A 171
 None
 1.46A 2ejfB-4jf8A:
undetectable		 2ejfB-4jf8A:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KC4_E_RBFE201_2
(RIBOFLAVIN
TRANSPORTER RIBU)		 4jf8 TRWG COMPONENT OF
TYPE IV SECRETION
SYSTEM
(Bartonella
birtlesii) 		3 / 3 LYS A 153
ASP A 181
ILE A 117
 None
 0.82A 5kc4E-4jf8A:
undetectable		 5kc4E-4jf8A:
23.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MWY_A_YNUA1101_1
(MINERALOCORTICOID
RECEPTOR)		 4jf8 TRWG COMPONENT OF
TYPE IV SECRETION
SYSTEM
(Bartonella
birtlesii) 		4 / 6 GLN A 104
PHE A 217
THR A 224
PHE A 175
 None
 1.48A 5mwyA-4jf8A:
undetectable		 5mwyA-4jf8A:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XV7_A_EMHA705_2
(SERINE-ARGININE (SR)
PROTEIN KINASE 1)		 4jf8 TRWG COMPONENT OF
TYPE IV SECRETION
SYSTEM
(Bartonella
birtlesii) 		4 / 4 VAL A 219
LEU A 127
LEU A 126
ASP A 209
 None
 1.49A 5xv7A-4jf8A:
2.7		 5xv7A-4jf8A:
20.44