SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4jfz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICT_D_T44D129_2
(TRANSTHYRETIN)		 4jfz FAB LIGHT CHAIN
(Homo
sapiens) 		4 / 7 LEU L 135
THR L 172
SER L 162
THR L 164
 None
 0.78A 1ictD-4jfzL:
4.0		 1ictD-4jfzL:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M8H_A_H4BA902_1
(INDUCIBLE NITRIC
OXIDE SYNTHASE)		 4jfz FAB LIGHT CHAIN
(Homo
sapiens) 		4 / 5 SER L  49
MET L  33
ILE L  48
TRP L  35
 None
 1.39A 1m8hA-4jfzL:
0.0		 1m8hA-4jfzL:
17.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M8H_B_H4BB903_1
(INDUCIBLE NITRIC
OXIDE SYNTHASE)		 4jfz FAB LIGHT CHAIN
(Homo
sapiens) 		4 / 5 SER L  49
MET L  33
ILE L  48
TRP L  35
 None
 1.42A 1m8hB-4jfzL:
0.0		 1m8hB-4jfzL:
17.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M8I_B_H4BB903_1
(INDUCIBLE NITRIC
OXIDE SYNTHASE)		 4jfz FAB LIGHT CHAIN
(Homo
sapiens) 		4 / 5 SER L  49
MET L  33
ILE L  48
TRP L  35
 None
 1.46A 1m8iB-4jfzL:
0.0		 1m8iB-4jfzL:
17.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R35_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 4jfz FAB LIGHT CHAIN
(Homo
sapiens) 		4 / 5 SER L  49
MET L  33
ILE L  48
TRP L  35
 None
 1.46A 1r35A-4jfzL:
0.0		 1r35A-4jfzL:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R35_B_H4BB1902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 4jfz FAB LIGHT CHAIN
(Homo
sapiens) 		4 / 5 SER L  49
MET L  33
ILE L  48
TRP L  35
 None
 1.44A 1r35B-4jfzL:
0.0		 1r35B-4jfzL:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOJ_C_FRDC305_1
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 4jfz FAB LIGHT CHAIN
(Homo
sapiens) 		4 / 5 LEU L 179
GLY L 128
PRO L 120
VAL L 132
 None
 0.89A 2aojA-4jfzL:
undetectable		 2aojA-4jfzL:
16.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DPZ_A_TYLA2001_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 4jfz FAB LIGHT CHAIN
(Homo
sapiens) 		4 / 6 LEU L 179
ALA L 130
HIS L 189
ASP L 151
 None
 1.35A 2dpzA-4jfzL:
undetectable		 2dpzA-4jfzL:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E67_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 4jfz FAB LIGHT CHAIN
(Homo
sapiens) 		4 / 5 SER L  49
MET L  33
ILE L  48
TRP L  35
 None
 1.44A 3e67B-4jfzL:
0.0		 3e67B-4jfzL:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E6L_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 4jfz FAB LIGHT CHAIN
(Homo
sapiens) 		4 / 5 SER L  49
MET L  33
ILE L  48
TRP L  35
 None
 1.36A 3e6lA-4jfzL:
0.0		 3e6lA-4jfzL:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E6N_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 4jfz FAB LIGHT CHAIN
(Homo
sapiens) 		4 / 5 SER L  49
MET L  33
ILE L  48
TRP L  35
 None
 1.31A 3e6nA-4jfzL:
0.0		 3e6nA-4jfzL:
17.42