SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4jg3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BX4_A_ADNA350_1
(PROTEIN (ADENOSINE
KINASE))		 4jg3 CATABOLITE
REPRESSION CONTROL
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 12 LEU A  58
GLY A  69
CYH A  61
ALA A  60
LEU A  46
 None
 0.97A 1bx4A-4jg3A:
undetectable		 1bx4A-4jg3A:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IBG_H_OBNH1_1
(IGG2B-KAPPA 40-50
FAB (HEAVY CHAIN))		 4jg3 CATABOLITE
REPRESSION CONTROL
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 6 LEU A 260
PHE A 102
TYR A  59
VAL A 105
 None
 1.30A 1ibgH-4jg3A:
undetectable		 1ibgH-4jg3A:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XF3_A_J01A500_1
(ORF12)		 4jg3 CATABOLITE
REPRESSION CONTROL
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 10 VAL A  11
LEU A 111
ARG A  96
GLY A  95
ALA A  63
 None
 1.15A 2xf3A-4jg3A:
undetectable		 2xf3A-4jg3A:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AY0_B_ADNB402_1
(UNCHARACTERIZED
PROTEIN MJ0883)		 4jg3 CATABOLITE
REPRESSION CONTROL
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 10 TYR A 148
GLY A 150
ILE A   6
VAL A 254
LEU A 227
 None
 1.16A 3ay0B-4jg3A:
undetectable		 3ay0B-4jg3A:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWW_A_SFXA801_1
(TRANSPORTER)		 4jg3 CATABOLITE
REPRESSION CONTROL
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 12 LEU A  22
GLY A  21
LEU A  23
ILE A  14
PHE A  51
 None
 1.01A 3gwwA-4jg3A:
undetectable		 3gwwA-4jg3A:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ROD_D_NCAD302_0
(NICOTINAMIDE
N-METHYLTRANSFERASE)		 4jg3 CATABOLITE
REPRESSION CONTROL
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 7 TYR A 135
ALA A 108
ASP A 101
TYR A  97
 None
 1.09A 3rodD-4jg3A:
undetectable		 3rodD-4jg3A:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C8B_A_0LIA1000_2
(RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 2)		 4jg3 CATABOLITE
REPRESSION CONTROL
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 5 VAL A 105
ILE A   7
TYR A 148
ILE A  34
 None
 0.86A 4c8bA-4jg3A:
undetectable		 4c8bA-4jg3A:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CEV_D_GAID410_0
(PROTEIN (ARGINASE))		 4jg3 CATABOLITE
REPRESSION CONTROL
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 6 ARG A 195
HIS A 156
MET A 159
ASP A 160
 None
 1.13A 4cevD-4jg3A:
undetectable
4cevE-4jg3A:
undetectable		 4cevD-4jg3A:
22.50
4cevE-4jg3A:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CEV_F_GAIF411_0
(PROTEIN (ARGINASE))		 4jg3 CATABOLITE
REPRESSION CONTROL
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 6 ARG A 195
HIS A 156
MET A 159
ASP A 160
 None
 1.17A 4cevE-4jg3A:
undetectable
4cevF-4jg3A:
undetectable		 4cevE-4jg3A:
22.50
4cevF-4jg3A:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QCK_A_ASDA404_1
(3-KETOSTEROID-9-ALPH
A-MONOOXYGENASE
OXYGENASE SUBUNIT)		 4jg3 CATABOLITE
REPRESSION CONTROL
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 12 VAL A   9
LEU A  46
ALA A  17
ASN A  12
GLY A  69
 None
 1.32A 4qckA-4jg3A:
undetectable		 4qckA-4jg3A:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W7B_B_PA1B204_1
(ACYLOXYACYL
HYDROLASE SMALL
SUBUNIT
ACYLOXYACYL
HYDROLASE LARGE
SUBUNIT)		 4jg3 CATABOLITE
REPRESSION CONTROL
PROTEIN
(Pseudomonas
aeruginosa) 		3 / 3 GLY A 219
ASN A 217
ARG A 245
 None
 0.75A 5w7bD-4jg3A:
undetectable		 5w7bD-4jg3A:
13.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F88_B_STRB502_1
(CYTOCHROME P450
CYP260A1)		 4jg3 CATABOLITE
REPRESSION CONTROL
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 6 LEU A  23
ALA A  18
LEU A  58
SER A  50
 None
 0.84A 6f88B-4jg3A:
undetectable		 6f88B-4jg3A:
13.13