SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4jg5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HSH_A_MK1A401_2
(HIV-II PROTEASE)		 4jg5 PUTATIVE CELL
ADHESION PROTEIN
(Parabacteroides
distasonis) 		5 / 9 ALA A 300
ILE A 326
VAL A 281
ILE A 215
ILE A 358
 None
 0.93A 1hshB-4jg5A:
undetectable		 1hshB-4jg5A:
16.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 4jg5 PUTATIVE CELL
ADHESION PROTEIN
(Parabacteroides
distasonis) 		5 / 12 ALA A  89
LEU A  86
ASN A  64
ALA A 112
ALA A  41
 None
 0.99A 1sa1A-4jg5A:
undetectable
1sa1B-4jg5A:
undetectable		 1sa1A-4jg5A:
23.04
1sa1B-4jg5A:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		 4jg5 PUTATIVE CELL
ADHESION PROTEIN
(Parabacteroides
distasonis) 		5 / 12 LEU A 356
PHE A 328
LEU A 191
ILE A 194
ILE A 210
 None
 0.84A 2bxqA-4jg5A:
undetectable		 2bxqA-4jg5A:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I2Z_A_SALA1100_1
(SERUM ALBUMIN)		 4jg5 PUTATIVE CELL
ADHESION PROTEIN
(Parabacteroides
distasonis) 		4 / 5 LEU A 356
LEU A 191
ILE A 194
ILE A 210
 None
 0.75A 2i2zA-4jg5A:
undetectable		 2i2zA-4jg5A:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y00_B_Y00B601_2
(BETA-1 ADRENERGIC
RECEPTOR)		 4jg5 PUTATIVE CELL
ADHESION PROTEIN
(Parabacteroides
distasonis) 		3 / 3 VAL A 192
ASN A  55
TRP A 365
 None
 0.99A 2y00B-4jg5A:
undetectable		 2y00B-4jg5A:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A8I_A_C2FA401_0
(AMINOMETHYLTRANSFERA
SE)		 4jg5 PUTATIVE CELL
ADHESION PROTEIN
(Parabacteroides
distasonis) 		5 / 12 ILE A 109
TYR A 125
VAL A 149
PHE A 128
ARG A 318
 None
 1.20A 3a8iA-4jg5A:
undetectable		 3a8iA-4jg5A:
23.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A8I_B_C2FB401_0
(AMINOMETHYLTRANSFERA
SE)		 4jg5 PUTATIVE CELL
ADHESION PROTEIN
(Parabacteroides
distasonis) 		5 / 12 ILE A 109
TYR A 125
VAL A 149
PHE A 128
ARG A 318
 None
 1.18A 3a8iB-4jg5A:
undetectable		 3a8iB-4jg5A:
23.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A8I_C_C2FC401_0
(AMINOMETHYLTRANSFERA
SE)		 4jg5 PUTATIVE CELL
ADHESION PROTEIN
(Parabacteroides
distasonis) 		5 / 12 ILE A 109
TYR A 125
VAL A 149
PHE A 128
ARG A 318
 None
 1.19A 3a8iC-4jg5A:
undetectable		 3a8iC-4jg5A:
23.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A8I_D_C2FD401_0
(AMINOMETHYLTRANSFERA
SE)		 4jg5 PUTATIVE CELL
ADHESION PROTEIN
(Parabacteroides
distasonis) 		5 / 12 ILE A 109
TYR A 125
VAL A 149
PHE A 128
ARG A 318
 None
 1.20A 3a8iD-4jg5A:
undetectable		 3a8iD-4jg5A:
23.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D4S_A_TIMA401_2
(BETA-2 ADRENERGIC
RECEPTOR/T4-LYSOZYME
CHIMERA)		 4jg5 PUTATIVE CELL
ADHESION PROTEIN
(Parabacteroides
distasonis) 		3 / 3 THR A 233
SER A 222
PHE A 128
 None
 0.82A 3d4sA-4jg5A:
undetectable		 3d4sA-4jg5A:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O01_B_DXCB1_0
(CELL INVASION
PROTEIN SIPD)		 4jg5 PUTATIVE CELL
ADHESION PROTEIN
(Parabacteroides
distasonis) 		5 / 9 ARG A 107
ILE A 150
ASN A  72
ALA A 106
LEU A 163
 None
 1.17A 3o01A-4jg5A:
undetectable
3o01B-4jg5A:
undetectable		 3o01A-4jg5A:
21.71
3o01B-4jg5A:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WS0_A_URFA301_1
(URACIL-DNA
GLYCOSYLASE)		 4jg5 PUTATIVE CELL
ADHESION PROTEIN
(Parabacteroides
distasonis) 		4 / 7 GLY A 169
GLN A 171
SER A 177
ASN A 172
 None
 1.13A 4ws0A-4jg5A:
undetectable		 4ws0A-4jg5A:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y03_A_SALA801_1
(PROTEIN POLYBROMO-1)		 4jg5 PUTATIVE CELL
ADHESION PROTEIN
(Parabacteroides
distasonis) 		4 / 7 ILE A 194
LEU A 356
ALA A 283
ILE A 210
 None
 0.85A 4y03A-4jg5A:
undetectable		 4y03A-4jg5A:
16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E4D_B_BEZB201_0
(HYDROXYNITRILE LYASE)		 4jg5 PUTATIVE CELL
ADHESION PROTEIN
(Parabacteroides
distasonis) 		5 / 11 VAL A  70
VAL A  68
ILE A 176
ILE A 180
LEU A  35
 None
 1.02A 5e4dB-4jg5A:
undetectable		 5e4dB-4jg5A:
18.38