SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4jg9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E1Q_A_SALA2006_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 4jg9 LIPOPROTEIN
(Bacillus
anthracis) 		4 / 6 THR A 115
VAL A 114
LEU A  47
ALA A  41
 None
 0.99A 2e1qA-4jg9A:
undetectable		 2e1qA-4jg9A:
9.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E1Q_C_SALC4006_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 4jg9 LIPOPROTEIN
(Bacillus
anthracis) 		4 / 6 THR A 115
VAL A 114
LEU A  47
ALA A  41
 None
 0.93A 2e1qC-4jg9A:
undetectable		 2e1qC-4jg9A:
9.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AX7_A_SALA1336_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 4jg9 LIPOPROTEIN
(Bacillus
anthracis) 		4 / 8 THR A 115
VAL A 114
LEU A  47
ALA A  41
 None
 1.00A 3ax7A-4jg9A:
undetectable		 3ax7A-4jg9A:
9.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNI_A_SALA1344_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 4jg9 LIPOPROTEIN
(Bacillus
anthracis) 		4 / 7 THR A 115
VAL A 114
LEU A  47
ALA A  41
 None
 1.01A 3uniA-4jg9A:
undetectable		 3uniA-4jg9A:
9.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W9N_C_CCSC1548_0
(ENOYL-[ACYL-CARRIER-
PROTEIN] REDUCTASE)		 4jg9 LIPOPROTEIN
(Bacillus
anthracis) 		3 / 3 ALA A 108
TRP A 155
VAL A 156
 None
 0.43A 4w9nC-4jg9A:
undetectable		 4w9nC-4jg9A:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_Z_BEZZ801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 4jg9 LIPOPROTEIN
(Bacillus
anthracis) 		4 / 4 ILE A 171
GLY A 153
ILE A  82
LEU A 154
 None
 0.81A 5dzkl-4jg9A:
undetectable
5dzkz-4jg9A:
undetectable		 5dzkl-4jg9A:
18.72
5dzkz-4jg9A:
22.22