SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4jgb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FDU_A_ESTA351_1
(17-BETA-HYDROXYSTERO
ID DEHYDROGENASE)		 4jgb PUTATIVE EXPORTED
PROTEIN
(Burkholderia
pseudomallei) 		5 / 12 VAL A 101
GLY A 102
GLY A  70
PRO A  71
LEU A 155
 None
None
SO4  A 302 (-3.1A)
SO4  A 302 (-3.1A)
None
 0.79A 1fduA-4jgbA:
13.4		 1fduA-4jgbA:
24.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N49_B_RITB301_1
(PROTEASE)		 4jgb PUTATIVE EXPORTED
PROTEIN
(Burkholderia
pseudomallei) 		4 / 7 GLY A  14
PRO A 158
ALA A 157
ILE A 156
 None
 0.77A 1n49A-4jgbA:
undetectable		 1n49A-4jgbA:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_A_SAMA801_0
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 4jgb PUTATIVE EXPORTED
PROTEIN
(Burkholderia
pseudomallei) 		5 / 12 THR A 206
ALA A 204
GLY A 105
GLY A 103
LEU A 115
 None
 0.98A 1rjdA-4jgbA:
undetectable		 1rjdA-4jgbA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_B_SAMB802_0
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 4jgb PUTATIVE EXPORTED
PROTEIN
(Burkholderia
pseudomallei) 		5 / 12 THR A 206
ALA A 204
GLY A 105
GLY A 103
LEU A 115
 None
 1.01A 1rjdB-4jgbA:
3.7		 1rjdB-4jgbA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_C_SAMC803_0
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 4jgb PUTATIVE EXPORTED
PROTEIN
(Burkholderia
pseudomallei) 		5 / 12 THR A 206
ALA A 204
GLY A 105
GLY A 103
LEU A 115
 None
 1.02A 1rjdC-4jgbA:
3.6		 1rjdC-4jgbA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOF_C_FRDC305_1
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 4jgb PUTATIVE EXPORTED
PROTEIN
(Burkholderia
pseudomallei) 		4 / 5 GLY A  11
PRO A 158
ALA A 157
ILE A 156
 SO4  A 302 (-3.3A)
None
None
None
 0.79A 2aofA-4jgbA:
undetectable		 2aofA-4jgbA:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOF_C_FRDC305_1
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 4jgb PUTATIVE EXPORTED
PROTEIN
(Burkholderia
pseudomallei) 		4 / 5 GLY A  14
PRO A 158
ALA A 157
ILE A 156
 None
 0.77A 2aofA-4jgbA:
undetectable		 2aofA-4jgbA:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_C_SVRC505_2
(PHOSPHOLIPASE A2)		 4jgb PUTATIVE EXPORTED
PROTEIN
(Burkholderia
pseudomallei) 		4 / 5 VAL A  64
VAL A  65
PHE A 150
ARG A  91
 None
 1.23A 3bjwH-4jgbA:
undetectable		 3bjwH-4jgbA:
15.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_G_SVRG506_2
(PHOSPHOLIPASE A2)		 4jgb PUTATIVE EXPORTED
PROTEIN
(Burkholderia
pseudomallei) 		4 / 5 VAL A  64
VAL A  65
PHE A 150
ARG A  91
 None
 1.16A 3bjwB-4jgbA:
undetectable		 3bjwB-4jgbA:
15.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGJ_A_CTYA402_2
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 4jgb PUTATIVE EXPORTED
PROTEIN
(Burkholderia
pseudomallei) 		4 / 5 PRO A  71
LEU A 172
TYR A 209
PHE A 165
 SO4  A 302 (-3.1A)
None
None
None
 1.37A 5igjA-4jgbA:
undetectable		 5igjA-4jgbA:
24.53