SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4jge'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P91_B_SAMB2401_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE A)		 4jge RED FLUORESCENT
PROTEIN BLFP-R5
(Branchiostoma
lanceolatum) 		5 / 12 TYR A  75
GLY A 179
GLY A  82
ILE A 182
THR A 174
 None
 1.05A 1p91B-4jgeA:
undetectable		 1p91B-4jgeA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F7F_A_NIOA601_1
(NICOTINATE
PHOSPHORIBOSYLTRANSF
ERASE, PUTATIVE)		 4jge RED FLUORESCENT
PROTEIN BLFP-R5
(Branchiostoma
lanceolatum) 		4 / 6 ARG A 196
GLY A 154
THR A 174
ARG A  89
 CR2  A  58 ( 3.9A)
None
None
CR2  A  58 ( 2.7A)
 1.16A 2f7fA-4jgeA:
undetectable		 2f7fA-4jgeA:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HC4_A_VDXA525_2
(VITAMIN D RECEPTOR)		 4jge RED FLUORESCENT
PROTEIN BLFP-R5
(Branchiostoma
lanceolatum) 		4 / 7 LEU A   9
LEU A  22
ILE A  15
SER A  47
 None
 1.23A 2hc4A-4jgeA:
undetectable		 2hc4A-4jgeA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6F_C_010C6_0
(INFECTIOUS
BRONCHITIS VIRUS
(IBV) MAIN PROTEASE
N-[(5-METHYLISOXAZOL
-3-YL)CARBONYL]ALANY
L-L-VALYL-N~1~-((1R,
2Z)-4-(BENZYLOXY)-4-
OXO-1-{[(3R)-2-OXOPY
RROLIDIN-3-YL]METHYL
}BUT-2-ENYL)-L-LEUCI
NAMIDE)		 4jge RED FLUORESCENT
PROTEIN BLFP-R5
(Branchiostoma
lanceolatum) 		3 / 3 ASN A 208
LEU A 200
HIS A 202
 None
 0.81A 2q6fB-4jgeA:
undetectable		 2q6fB-4jgeA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A8I_A_C2FA401_0
(AMINOMETHYLTRANSFERA
SE)		 4jge RED FLUORESCENT
PROTEIN BLFP-R5
(Branchiostoma
lanceolatum) 		5 / 12 ILE A 152
TYR A 146
PHE A 178
TYR A  62
ARG A 196
 None
None
None
CR2  A  58 ( 3.5A)
CR2  A  58 ( 3.9A)
 1.10A 3a8iA-4jgeA:
undetectable		 3a8iA-4jgeA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A8I_B_C2FB401_0
(AMINOMETHYLTRANSFERA
SE)		 4jge RED FLUORESCENT
PROTEIN BLFP-R5
(Branchiostoma
lanceolatum) 		5 / 12 ILE A 152
TYR A 146
PHE A 178
TYR A  62
ARG A 196
 None
None
None
CR2  A  58 ( 3.5A)
CR2  A  58 ( 3.9A)
 1.13A 3a8iB-4jgeA:
undetectable		 3a8iB-4jgeA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A8I_C_C2FC401_0
(AMINOMETHYLTRANSFERA
SE)		 4jge RED FLUORESCENT
PROTEIN BLFP-R5
(Branchiostoma
lanceolatum) 		5 / 12 ILE A 152
TYR A 146
PHE A 178
TYR A  62
ARG A 196
 None
None
None
CR2  A  58 ( 3.5A)
CR2  A  58 ( 3.9A)
 1.18A 3a8iC-4jgeA:
undetectable		 3a8iC-4jgeA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A8I_D_C2FD401_0
(AMINOMETHYLTRANSFERA
SE)		 4jge RED FLUORESCENT
PROTEIN BLFP-R5
(Branchiostoma
lanceolatum) 		5 / 12 ILE A 152
TYR A 146
PHE A 178
TYR A  62
ARG A 196
 None
None
None
CR2  A  58 ( 3.5A)
CR2  A  58 ( 3.9A)
 1.12A 3a8iD-4jgeA:
undetectable		 3a8iD-4jgeA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF509_2
(PHOSPHOLIPASE A2)		 4jge RED FLUORESCENT
PROTEIN BLFP-R5
(Branchiostoma
lanceolatum) 		4 / 8 ASN A 150
LYS A 180
PRO A  74
PHE A  67
 None
 1.41A 3bjwD-4jgeA:
undetectable		 3bjwD-4jgeA:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OI8_A_ADNA2_1
(UNCHARACTERIZED
PROTEIN)		 4jge RED FLUORESCENT
PROTEIN BLFP-R5
(Branchiostoma
lanceolatum) 		4 / 6 ILE A  11
ASN A  56
HIS A 103
LEU A   9
 None
 1.21A 3oi8A-4jgeA:
undetectable		 3oi8A-4jgeA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YVX_A_GMRA401_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 4jge RED FLUORESCENT
PROTEIN BLFP-R5
(Branchiostoma
lanceolatum) 		5 / 12 TYR A 168
TYR A 160
LEU A  46
SER A  47
ASN A  56
 None
 1.39A 4yvxA-4jgeA:
undetectable		 4yvxA-4jgeA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YVX_B_GMRB401_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 4jge RED FLUORESCENT
PROTEIN BLFP-R5
(Branchiostoma
lanceolatum) 		5 / 12 TYR A 168
TYR A 160
LEU A  46
SER A  47
ASN A  56
 None
 1.38A 4yvxB-4jgeA:
undetectable		 4yvxB-4jgeA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJ8_A_SUVA2001_1
(HUMAN OX1R FUSION
PROTEIN TO P.ABYSII
GLYCOGEN SYNTHASE)		 4jge RED FLUORESCENT
PROTEIN BLFP-R5
(Branchiostoma
lanceolatum) 		5 / 12 VAL A 176
GLN A 211
PHE A 209
HIS A 103
TYR A 105
 None
CR2  A  58 ( 3.4A)
CR2  A  58 ( 4.6A)
None
CR2  A  58 ( 4.6A)
 1.31A 4zj8A-4jgeA:
undetectable		 4zj8A-4jgeA:
15.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IK1_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 4jge RED FLUORESCENT
PROTEIN BLFP-R5
(Branchiostoma
lanceolatum) 		4 / 5 PHE A  61
LEU A  39
GLY A  24
ILE A 112
 CR2  A  58 ( 3.6A)
None
None
None
 0.95A 5ik1A-4jgeA:
undetectable		 5ik1A-4jgeA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DRZ_A_H8JA1206_0
(5HT2B RECEPTOR, BRIL
CHIMERA)		 4jge RED FLUORESCENT
PROTEIN BLFP-R5
(Branchiostoma
lanceolatum) 		5 / 12 VAL A  54
LEU A  53
PHE A  20
GLY A  17
PHE A 123
 None
 1.04A 6drzA-4jgeA:
undetectable		 6drzA-4jgeA:
20.29