SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4jgj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M24_A_9CRA501_1
(RETINOIC ACID
RECEPTOR GAMMA)
4jgj CARCINOEMBRYONIC
ANTIGEN-RELATED CELL
ADHESION MOLECULE 15

(Mus
musculus)
5 / 12 ALA A  74
LEU A  85
GLY A  91
LEU A 103
ILE A  95
None
1.05A 5m24A-4jgjA:
undetectable
5m24A-4jgjA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA309_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)
4jgj CARCINOEMBRYONIC
ANTIGEN-RELATED CELL
ADHESION MOLECULE 15

(Mus
musculus)
4 / 4 LEU A 116
GLY A  99
SER A 100
SER A  48
None
1.37A 5uunA-4jgjA:
undetectable
5uunA-4jgjA:
17.75