SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4jgl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JC9_A_ADNA1497_1
(CYTOSOLIC PURINE
5'-NUCLEOTIDASE)		 4jgl HYPOTHETICAL PROTEIN
(Bacteroides
eggerthii) 		4 / 7 ASP A 141
THR A 139
ILE A 137
ASN A 100
 None
CA  A 202 (-3.6A)
None
None
 1.26A 2jc9A-4jglA:
undetectable		 2jc9A-4jglA:
14.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DR2_A_PARA1609_1
(16S RRNA
30S RIBOSOMAL
PROTEIN S9
30S RIBOSOMAL
PROTEIN S10)		 4jgl HYPOTHETICAL PROTEIN
(Bacteroides
eggerthii) 		3 / 3 TYR A  69
ARG A 167
SER A  44
 None
UNL  A 200 ( 3.9A)
None
 1.17A 4dr2I-4jglA:
undetectable
4dr2J-4jglA:
undetectable		 4dr2I-4jglA:
20.47
4dr2J-4jglA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U4S_B_BEZB301_0
(PUTATIVE SHORT CHAIN
DEHYDROGENASE)		 4jgl HYPOTHETICAL PROTEIN
(Bacteroides
eggerthii) 		4 / 8 ILE A  89
LEU A  78
MET A  71
LEU A  76
 None
 0.99A 5u4sB-4jglA:
undetectable		 5u4sB-4jglA:
20.33