SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4jgn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICU_D_NIOD223_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 4jgn RNA SILENCING
SUPPRESSOR P19
(Tomato
bushy
stunt
virus) 		4 / 5 PHE A  94
GLY A  36
SER A  60
THR A  57
 None
 1.27A 1icuC-4jgnA:
undetectable
1icuD-4jgnA:
undetectable		 1icuC-4jgnA:
21.00
1icuD-4jgnA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6J_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4jgn RNA SILENCING
SUPPRESSOR P19
(Tomato
bushy
stunt
virus) 		4 / 7 ARG A  56
VAL A  97
PHE A  94
GLU A 121
 None
 1.44A 1p6jA-4jgnA:
undetectable
1p6jB-4jgnA:
undetectable		 1p6jA-4jgnA:
17.46
1p6jB-4jgnA:
17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4jgn RNA SILENCING
SUPPRESSOR P19
(Tomato
bushy
stunt
virus) 		4 / 7 ARG A  56
VAL A  97
PHE A  94
GLU A 121
 None
 1.42A 3ufoA-4jgnA:
undetectable
3ufoB-4jgnA:
undetectable		 3ufoA-4jgnA:
17.46
3ufoB-4jgnA:
17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4jgn RNA SILENCING
SUPPRESSOR P19
(Tomato
bushy
stunt
virus) 		4 / 7 ARG A  56
VAL A  97
PHE A  94
GLU A 121
 None
 1.47A 3ufpA-4jgnA:
undetectable
3ufpB-4jgnA:
undetectable		 3ufpA-4jgnA:
17.46
3ufpB-4jgnA:
17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFQ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4jgn RNA SILENCING
SUPPRESSOR P19
(Tomato
bushy
stunt
virus) 		4 / 6 ARG A  56
VAL A  97
PHE A  94
GLU A 121
 None
 1.49A 3ufqA-4jgnA:
undetectable
3ufqB-4jgnA:
undetectable		 3ufqA-4jgnA:
17.46
3ufqB-4jgnA:
17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4jgn RNA SILENCING
SUPPRESSOR P19
(Tomato
bushy
stunt
virus) 		4 / 7 ARG A  56
VAL A  97
PHE A  94
GLU A 121
 None
 1.48A 4caoA-4jgnA:
undetectable
4caoB-4jgnA:
undetectable		 4caoA-4jgnA:
17.46
4caoB-4jgnA:
17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4jgn RNA SILENCING
SUPPRESSOR P19
(Tomato
bushy
stunt
virus) 		4 / 6 ARG A  56
VAL A  97
PHE A  94
GLU A 121
 None
 1.45A 4kcnA-4jgnA:
undetectable
4kcnB-4jgnA:
undetectable		 4kcnA-4jgnA:
17.46
4kcnB-4jgnA:
17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNV_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4jgn RNA SILENCING
SUPPRESSOR P19
(Tomato
bushy
stunt
virus) 		4 / 6 ARG A  56
VAL A  97
PHE A  94
GLU A 121
 None
 1.45A 5unvA-4jgnA:
undetectable
5unvB-4jgnA:
undetectable		 5unvA-4jgnA:
17.46
5unvB-4jgnA:
17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNV_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4jgn RNA SILENCING
SUPPRESSOR P19
(Tomato
bushy
stunt
virus) 		4 / 6 PHE A  94
GLU A 121
ARG A  56
VAL A  97
 None
 1.47A 5unvA-4jgnA:
undetectable
5unvB-4jgnA:
undetectable		 5unvA-4jgnA:
17.46
5unvB-4jgnA:
17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUJ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4jgn RNA SILENCING
SUPPRESSOR P19
(Tomato
bushy
stunt
virus) 		4 / 7 ARG A  56
VAL A  97
PHE A  94
GLU A 121
 None
 1.42A 5vujA-4jgnA:
undetectable
5vujB-4jgnA:
undetectable		 5vujA-4jgnA:
17.46
5vujB-4jgnA:
17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUS_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4jgn RNA SILENCING
SUPPRESSOR P19
(Tomato
bushy
stunt
virus) 		4 / 7 PHE A  94
GLU A 121
ARG A  56
VAL A  97
 None
 1.46A 5vusA-4jgnA:
undetectable
5vusB-4jgnA:
undetectable		 5vusA-4jgnA:
17.46
5vusB-4jgnA:
17.46