SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4jgp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EE2_B_CHDB1250_0
(ALCOHOL
DEHYDROGENASE)		 4jgp SPORULATION KINASE D
(Bacillus
subtilis) 		3 / 3 MET A  73
LEU A  76
SER A  77
 None
 0.48A 1ee2A-4jgpA:
undetectable		 1ee2A-4jgpA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK3_A_T44A3004_1
(SERUM ALBUMIN)		 4jgp SPORULATION KINASE D
(Bacillus
subtilis) 		4 / 7 GLU A 121
LEU A 122
VAL A 115
LEU A  93
 None
 1.01A 1hk3A-4jgpA:
undetectable		 1hk3A-4jgpA:
17.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_H_CLMH221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 4jgp SPORULATION KINASE D
(Bacillus
subtilis) 		5 / 12 THR A 120
SER A 118
LEU A 109
PHE A 133
VAL A 177
 None
 1.25A 3u9fH-4jgpA:
undetectable
3u9fI-4jgpA:
undetectable		 3u9fH-4jgpA:
20.23
3u9fI-4jgpA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A81_A_DXCA1161_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 4jgp SPORULATION KINASE D
(Bacillus
subtilis) 		5 / 12 ILE A 153
GLY A 105
ASN A 110
MET A  89
LEU A  93
 PYR  A 301 (-3.9A)
None
None
None
None
 1.23A 4a81A-4jgpA:
undetectable		 4a81A-4jgpA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M83_A_ERYA1400_0
(OLEANDOMYCIN
GLYCOSYLTRANSFERASE)		 4jgp SPORULATION KINASE D
(Bacillus
subtilis) 		5 / 11 ASN A 233
VAL A 201
ILE A 189
LEU A  54
ALA A 210
 None
 1.44A 4m83A-4jgpA:
undetectable		 4m83A-4jgpA:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_1_BEZ1801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 4jgp SPORULATION KINASE D
(Bacillus
subtilis) 		3 / 3 LEU A 188
PHE A 209
ILE A  62
 None
 0.73A 5dzk1-4jgpA:
undetectable
5dzkF-4jgpA:
undetectable
5dzkM-4jgpA:
undetectable		 5dzk1-4jgpA:
9.09
5dzkF-4jgpA:
20.65
5dzkM-4jgpA:
19.30