SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4jh8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1NKI_A_PPFA5001_1
(PROBABLE FOSFOMYCIN
RESISTANCE PROTEIN)		 4jh8 METALLOTHIOL
TRANSFERASE FOSB
(Bacillus
cereus) 		5 / 9 TYR A  64
HIS A  66
TYR A 105
GLU A 115
ARG A 124
 CYS  A 205 ( 4.3A)
ZN  A 201 ( 3.2A)
FCN  A 204 (-4.8A)
ZN  A 201 ( 2.5A)
FCN  A 204 (-2.9A)
 0.37A 1nkiA-4jh8A:
17.7
1nkiB-4jh8A:
17.5		 1nkiA-4jh8A:
35.25
1nkiB-4jh8A:
35.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1NKI_B_PPFB5002_1
(PROBABLE FOSFOMYCIN
RESISTANCE PROTEIN)		 4jh8 METALLOTHIOL
TRANSFERASE FOSB
(Bacillus
cereus) 		5 / 9 TYR A  64
HIS A  66
TYR A 105
GLU A 115
ARG A 124
 CYS  A 205 ( 4.3A)
ZN  A 201 ( 3.2A)
FCN  A 204 (-4.8A)
ZN  A 201 ( 2.5A)
FCN  A 204 (-2.9A)
 0.39A 1nkiA-4jh8A:
17.7
1nkiB-4jh8A:
17.5		 1nkiA-4jh8A:
35.25
1nkiB-4jh8A:
35.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UPF_C_URFC999_1
(URACIL
PHOSPHORIBOSYLTRANSF
ERASE)		 4jh8 METALLOTHIOL
TRANSFERASE FOSB
(Bacillus
cereus) 		4 / 5 ALA A  38
TYR A  22
ILE A  19
ASP A 108
 None
 1.14A 1upfC-4jh8A:
undetectable		 1upfC-4jh8A:
23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_D_RTZD2_1
(CYTOCHROME P450 2D6)		 4jh8 METALLOTHIOL
TRANSFERASE FOSB
(Bacillus
cereus) 		5 / 9 PHE A  69
LEU A   8
VAL A  45
LEU A  26
ILE A  42
 None
 1.08A 3tbgD-4jh8A:
undetectable		 3tbgD-4jh8A:
14.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_R_CLMR221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 4jh8 METALLOTHIOL
TRANSFERASE FOSB
(Bacillus
cereus) 		5 / 10 PHE A  69
PHE A 106
PHE A  21
LEU A  49
VAL A  12
 None
 1.45A 3u9fR-4jh8A:
undetectable		 3u9fR-4jh8A:
19.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IR0_A_FCNA202_1
(METALLOTHIOL
TRANSFERASE FOSB 2)		 4jh8 METALLOTHIOL
TRANSFERASE FOSB
(Bacillus
cereus) 		5 / 11 HIS A   7
CYH A   9
TRP A  46
ALA A  48
ASN A  50
 None
 0.25A 4ir0A-4jh8A:
20.7
4ir0B-4jh8A:
21.4		 4ir0A-4jh8A:
67.63
4ir0B-4jh8A:
67.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IR0_A_FCNA202_1
(METALLOTHIOL
TRANSFERASE FOSB 2)		 4jh8 METALLOTHIOL
TRANSFERASE FOSB
(Bacillus
cereus) 		6 / 11 TYR A  64
HIS A  66
ARG A  94
TYR A 105
GLU A 115
ARG A 124
 CYS  A 205 ( 4.3A)
ZN  A 201 ( 3.2A)
FCN  A 204 ( 3.9A)
FCN  A 204 (-4.8A)
ZN  A 201 ( 2.5A)
FCN  A 204 (-2.9A)
 0.20A 4ir0A-4jh8A:
20.7
4ir0B-4jh8A:
21.4		 4ir0A-4jh8A:
67.63
4ir0B-4jh8A:
67.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IR0_B_FCNB202_1
(METALLOTHIOL
TRANSFERASE FOSB 2)		 4jh8 METALLOTHIOL
TRANSFERASE FOSB
(Bacillus
cereus) 		5 / 11 HIS A   7
CYH A   9
TRP A  46
ALA A  48
ASN A  50
 None
 0.22A 4ir0A-4jh8A:
20.7
4ir0B-4jh8A:
21.4		 4ir0A-4jh8A:
67.63
4ir0B-4jh8A:
67.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IR0_B_FCNB202_1
(METALLOTHIOL
TRANSFERASE FOSB 2)		 4jh8 METALLOTHIOL
TRANSFERASE FOSB
(Bacillus
cereus) 		6 / 11 TYR A  64
HIS A  66
ARG A  94
TYR A 105
GLU A 115
ARG A 124
 CYS  A 205 ( 4.3A)
ZN  A 201 ( 3.2A)
FCN  A 204 ( 3.9A)
FCN  A 204 (-4.8A)
ZN  A 201 ( 2.5A)
FCN  A 204 (-2.9A)
 0.17A 4ir0A-4jh8A:
20.7
4ir0B-4jh8A:
21.4		 4ir0A-4jh8A:
67.63
4ir0B-4jh8A:
67.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4JD1_A_FCNA202_1
(METALLOTHIOL
TRANSFERASE FOSB 2)		 4jh8 METALLOTHIOL
TRANSFERASE FOSB
(Bacillus
cereus) 		6 / 12 HIS A   7
CYH A   9
TYR A  39
TRP A  46
ALA A  48
ASN A  50
 None
 0.28A 4jd1A-4jh8A:
20.7
4jd1B-4jh8A:
20.6		 4jd1A-4jh8A:
67.63
4jd1B-4jh8A:
67.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4JD1_A_FCNA202_1
(METALLOTHIOL
TRANSFERASE FOSB 2)		 4jh8 METALLOTHIOL
TRANSFERASE FOSB
(Bacillus
cereus) 		6 / 12 TYR A  64
HIS A  66
ARG A  94
TYR A 105
GLU A 115
ARG A 124
 CYS  A 205 ( 4.3A)
ZN  A 201 ( 3.2A)
FCN  A 204 ( 3.9A)
FCN  A 204 (-4.8A)
ZN  A 201 ( 2.5A)
FCN  A 204 (-2.9A)
 0.21A 4jd1A-4jh8A:
20.7
4jd1B-4jh8A:
20.6		 4jd1A-4jh8A:
67.63
4jd1B-4jh8A:
67.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4JD1_B_FCNB203_1
(METALLOTHIOL
TRANSFERASE FOSB 2)		 4jh8 METALLOTHIOL
TRANSFERASE FOSB
(Bacillus
cereus) 		6 / 12 HIS A   7
CYH A   9
TYR A  39
TRP A  46
ALA A  48
ASN A  50
 None
 0.20A 4jd1A-4jh8A:
20.7
4jd1B-4jh8A:
20.6		 4jd1A-4jh8A:
67.63
4jd1B-4jh8A:
67.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4JD1_B_FCNB203_1
(METALLOTHIOL
TRANSFERASE FOSB 2)		 4jh8 METALLOTHIOL
TRANSFERASE FOSB
(Bacillus
cereus) 		6 / 12 TYR A  64
HIS A  66
ARG A  94
TYR A 105
GLU A 115
ARG A 124
 CYS  A 205 ( 4.3A)
ZN  A 201 ( 3.2A)
FCN  A 204 ( 3.9A)
FCN  A 204 (-4.8A)
ZN  A 201 ( 2.5A)
FCN  A 204 (-2.9A)
 0.20A 4jd1A-4jh8A:
20.7
4jd1B-4jh8A:
20.6		 4jd1A-4jh8A:
67.63
4jd1B-4jh8A:
67.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4JH3_A_FCNA204_1
(METALLOTHIOL
TRANSFERASE FOSB)		 4jh8 METALLOTHIOL
TRANSFERASE FOSB
(Bacillus
cereus) 		6 / 12 HIS A   7
CYH A   9
TYR A  39
TRP A  46
ALA A  48
ASN A  50
 None
 0.13A 4jh3A-4jh8A:
23.6
4jh3B-4jh8A:
24.4		 4jh3A-4jh8A:
100.00
4jh3B-4jh8A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4JH3_A_FCNA204_1
(METALLOTHIOL
TRANSFERASE FOSB)		 4jh8 METALLOTHIOL
TRANSFERASE FOSB
(Bacillus
cereus) 		6 / 12 TYR A  64
HIS A  66
ARG A  94
TYR A 105
GLU A 115
ARG A 124
 CYS  A 205 ( 4.3A)
ZN  A 201 ( 3.2A)
FCN  A 204 ( 3.9A)
FCN  A 204 (-4.8A)
ZN  A 201 ( 2.5A)
FCN  A 204 (-2.9A)
 0.07A 4jh3A-4jh8A:
23.6
4jh3B-4jh8A:
24.4		 4jh3A-4jh8A:
100.00
4jh3B-4jh8A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4JH3_B_FCNB203_1
(METALLOTHIOL
TRANSFERASE FOSB)		 4jh8 METALLOTHIOL
TRANSFERASE FOSB
(Bacillus
cereus) 		5 / 11 HIS A   7
CYH A   9
TRP A  46
ALA A  48
ASN A  50
 None
 0.16A 4jh3A-4jh8A:
23.6
4jh3B-4jh8A:
24.4		 4jh3A-4jh8A:
100.00
4jh3B-4jh8A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4JH3_B_FCNB203_1
(METALLOTHIOL
TRANSFERASE FOSB)		 4jh8 METALLOTHIOL
TRANSFERASE FOSB
(Bacillus
cereus) 		6 / 11 TYR A  64
HIS A  66
ARG A  94
TYR A 105
GLU A 115
ARG A 124
 CYS  A 205 ( 4.3A)
ZN  A 201 ( 3.2A)
FCN  A 204 ( 3.9A)
FCN  A 204 (-4.8A)
ZN  A 201 ( 2.5A)
FCN  A 204 (-2.9A)
 0.10A 4jh3A-4jh8A:
23.6
4jh3B-4jh8A:
24.4		 4jh3A-4jh8A:
100.00
4jh3B-4jh8A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4JH4_A_FCNA202_1
(METALLOTHIOL
TRANSFERASE FOSB)		 4jh8 METALLOTHIOL
TRANSFERASE FOSB
(Bacillus
cereus) 		5 / 11 HIS A   7
CYH A   9
TRP A  46
ALA A  48
ASN A  50
 None
 0.13A 4jh4A-4jh8A:
24.3
4jh4B-4jh8A:
23.5		 4jh4A-4jh8A:
100.00
4jh4B-4jh8A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4JH4_A_FCNA202_1
(METALLOTHIOL
TRANSFERASE FOSB)		 4jh8 METALLOTHIOL
TRANSFERASE FOSB
(Bacillus
cereus) 		6 / 11 TYR A  64
HIS A  66
ARG A  94
TYR A 105
GLU A 115
ARG A 124
 CYS  A 205 ( 4.3A)
ZN  A 201 ( 3.2A)
FCN  A 204 ( 3.9A)
FCN  A 204 (-4.8A)
ZN  A 201 ( 2.5A)
FCN  A 204 (-2.9A)
 0.13A 4jh4A-4jh8A:
24.3
4jh4B-4jh8A:
23.5		 4jh4A-4jh8A:
100.00
4jh4B-4jh8A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4JH4_B_FCNB202_1
(METALLOTHIOL
TRANSFERASE FOSB)		 4jh8 METALLOTHIOL
TRANSFERASE FOSB
(Bacillus
cereus) 		5 / 11 HIS A   7
CYH A   9
TRP A  46
ALA A  48
ASN A  50
 None
 0.13A 4jh4A-4jh8A:
24.3
4jh4B-4jh8A:
23.5		 4jh4A-4jh8A:
100.00
4jh4B-4jh8A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4JH4_B_FCNB202_1
(METALLOTHIOL
TRANSFERASE FOSB)		 4jh8 METALLOTHIOL
TRANSFERASE FOSB
(Bacillus
cereus) 		6 / 11 TYR A  64
HIS A  66
ARG A  94
TYR A 105
GLU A 115
ARG A 124
 CYS  A 205 ( 4.3A)
ZN  A 201 ( 3.2A)
FCN  A 204 ( 3.9A)
FCN  A 204 (-4.8A)
ZN  A 201 ( 2.5A)
FCN  A 204 (-2.9A)
 0.11A 4jh4A-4jh8A:
24.3
4jh4B-4jh8A:
23.5		 4jh4A-4jh8A:
100.00
4jh4B-4jh8A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4JH5_A_FCNA202_1
(METALLOTHIOL
TRANSFERASE FOSB)		 4jh8 METALLOTHIOL
TRANSFERASE FOSB
(Bacillus
cereus) 		5 / 11 HIS A   7
CYH A   9
TRP A  46
ALA A  48
ASN A  50
 None
 0.16A 4jh5A-4jh8A:
24.3
4jh5B-4jh8A:
23.5		 4jh5A-4jh8A:
100.00
4jh5B-4jh8A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4JH5_A_FCNA202_1
(METALLOTHIOL
TRANSFERASE FOSB)		 4jh8 METALLOTHIOL
TRANSFERASE FOSB
(Bacillus
cereus) 		6 / 11 TYR A  64
HIS A  66
ARG A  94
TYR A 105
GLU A 115
ARG A 124
 CYS  A 205 ( 4.3A)
ZN  A 201 ( 3.2A)
FCN  A 204 ( 3.9A)
FCN  A 204 (-4.8A)
ZN  A 201 ( 2.5A)
FCN  A 204 (-2.9A)
 0.10A 4jh5A-4jh8A:
24.3
4jh5B-4jh8A:
23.5		 4jh5A-4jh8A:
100.00
4jh5B-4jh8A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4JH5_B_FCNB203_1
(METALLOTHIOL
TRANSFERASE FOSB)		 4jh8 METALLOTHIOL
TRANSFERASE FOSB
(Bacillus
cereus) 		5 / 11 HIS A   7
CYH A   9
TRP A  46
ALA A  48
ASN A  50
 None
 0.15A 4jh5A-4jh8A:
24.3
4jh5B-4jh8A:
23.5		 4jh5A-4jh8A:
100.00
4jh5B-4jh8A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4JH5_B_FCNB203_1
(METALLOTHIOL
TRANSFERASE FOSB)		 4jh8 METALLOTHIOL
TRANSFERASE FOSB
(Bacillus
cereus) 		6 / 11 TYR A  64
HIS A  66
ARG A  94
TYR A 105
GLU A 115
ARG A 124
 CYS  A 205 ( 4.3A)
ZN  A 201 ( 3.2A)
FCN  A 204 ( 3.9A)
FCN  A 204 (-4.8A)
ZN  A 201 ( 2.5A)
FCN  A 204 (-2.9A)
 0.06A 4jh5A-4jh8A:
24.3
4jh5B-4jh8A:
23.5		 4jh5A-4jh8A:
100.00
4jh5B-4jh8A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4JH6_A_FCNA202_1
(METALLOTHIOL
TRANSFERASE FOSB)		 4jh8 METALLOTHIOL
TRANSFERASE FOSB
(Bacillus
cereus) 		6 / 10 TYR A  64
HIS A  66
ARG A  94
TYR A 105
GLU A 115
ARG A 124
 CYS  A 205 ( 4.3A)
ZN  A 201 ( 3.2A)
FCN  A 204 ( 3.9A)
FCN  A 204 (-4.8A)
ZN  A 201 ( 2.5A)
FCN  A 204 (-2.9A)
 0.12A 4jh6A-4jh8A:
24.4
4jh6B-4jh8A:
23.6		 4jh6A-4jh8A:
100.00
4jh6B-4jh8A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4JH6_B_FCNB202_1
(METALLOTHIOL
TRANSFERASE FOSB)		 4jh8 METALLOTHIOL
TRANSFERASE FOSB
(Bacillus
cereus) 		6 / 10 TYR A  64
HIS A  66
ARG A  94
TYR A 105
GLU A 115
ARG A 124
 CYS  A 205 ( 4.3A)
ZN  A 201 ( 3.2A)
FCN  A 204 ( 3.9A)
FCN  A 204 (-4.8A)
ZN  A 201 ( 2.5A)
FCN  A 204 (-2.9A)
 0.09A 4jh6A-4jh8A:
24.4
4jh6B-4jh8A:
23.6		 4jh6A-4jh8A:
100.00
4jh6B-4jh8A:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IAO_C_URFC301_1
(BIFUNCTIONAL PROTEIN
PYRR)		 4jh8 METALLOTHIOL
TRANSFERASE FOSB
(Bacillus
cereus) 		3 / 3 ARG A  94
HIS A 117
ARG A  96
 FCN  A 204 ( 3.9A)
None
FCN  A 204 ( 4.4A)
 1.15A 5iaoC-4jh8A:
undetectable		 5iaoC-4jh8A:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IAO_F_URFF301_1
(BIFUNCTIONAL PROTEIN
PYRR)		 4jh8 METALLOTHIOL
TRANSFERASE FOSB
(Bacillus
cereus) 		3 / 3 ARG A  94
HIS A 117
ARG A  96
 FCN  A 204 ( 3.9A)
None
FCN  A 204 ( 4.4A)
 1.15A 5iaoF-4jh8A:
undetectable		 5iaoF-4jh8A:
22.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5V3D_A_FCNA205_1
(FOSFOMYCIN
RESISTANCE PROTEIN)		 4jh8 METALLOTHIOL
TRANSFERASE FOSB
(Bacillus
cereus) 		5 / 10 TYR A  64
HIS A  66
TYR A 105
GLU A 115
ARG A 124
 CYS  A 205 ( 4.3A)
ZN  A 201 ( 3.2A)
FCN  A 204 (-4.8A)
ZN  A 201 ( 2.5A)
FCN  A 204 (-2.9A)
 0.40A 5v3dA-4jh8A:
17.4
5v3dB-4jh8A:
17.5		 5v3dA-4jh8A:
38.57
5v3dB-4jh8A:
38.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AP6_A_TLFA300_0
(PROBABLE
STRIGOLACTONE
ESTERASE DAD2)		 4jh8 METALLOTHIOL
TRANSFERASE FOSB
(Bacillus
cereus) 		5 / 12 VAL A  88
PHE A  69
ILE A  42
VAL A  47
VAL A  25
 None
 1.18A 6ap6A-4jh8A:
undetectable		 6ap6A-4jh8A:
17.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AP6_B_TLFB300_0
(PROBABLE
STRIGOLACTONE
ESTERASE DAD2)		 4jh8 METALLOTHIOL
TRANSFERASE FOSB
(Bacillus
cereus) 		5 / 12 VAL A  88
PHE A  69
ILE A  42
VAL A  47
VAL A  25
 None
 1.17A 6ap6B-4jh8A:
undetectable		 6ap6B-4jh8A:
17.04