SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4jhi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FM4_A_DXCA1002_0
(MAJOR POLLEN
ALLERGEN BET V 1-L)		 4jhi MTN13 PROTEIN
(Medicago
truncatula) 		5 / 12 VAL A 148
TYR A  80
TYR A  82
ILE A  98
TYR A 120
 None
None
EMU  A 202 (-4.9A)
EMU  A 202 ( 4.9A)
None
 1.12A 1fm4A-4jhiA:
19.8		 1fm4A-4jhiA:
41.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PKV_A_RBFA100_1
(RIBOFLAVIN SYNTHASE
ALPHA CHAIN)		 4jhi MTN13 PROTEIN
(Medicago
truncatula) 		5 / 11 SER A  65
LEU A  57
THR A  58
ILE A  70
ILE A  54
 None
 1.09A 1pkvA-4jhiA:
undetectable
1pkvB-4jhiA:
undetectable		 1pkvA-4jhiA:
20.48
1pkvB-4jhiA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PKV_B_RBFB101_1
(RIBOFLAVIN SYNTHASE
ALPHA CHAIN)		 4jhi MTN13 PROTEIN
(Medicago
truncatula) 		5 / 11 ILE A  54
SER A  65
LEU A  57
THR A  58
ILE A  70
 None
 1.11A 1pkvA-4jhiA:
undetectable
1pkvB-4jhiA:
undetectable		 1pkvA-4jhiA:
20.48
1pkvB-4jhiA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_A_SAMA300_0
(PUTATIVE RRNA
METHYLASE)		 4jhi MTN13 PROTEIN
(Medicago
truncatula) 		5 / 12 ASP A 157
ILE A  23
GLY A  27
ASN A 155
LEU A  14
 None
 1.12A 3eeyA-4jhiA:
undetectable		 3eeyA-4jhiA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_B_SAMB300_0
(PUTATIVE RRNA
METHYLASE)		 4jhi MTN13 PROTEIN
(Medicago
truncatula) 		5 / 12 ASP A 157
ILE A  23
GLY A  27
ASN A 155
LEU A  14
 None
 1.15A 3eeyB-4jhiA:
undetectable		 3eeyB-4jhiA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_C_SAMC300_0
(PUTATIVE RRNA
METHYLASE)		 4jhi MTN13 PROTEIN
(Medicago
truncatula) 		5 / 12 ASP A 157
ILE A  23
GLY A  27
ASN A 155
LEU A  14
 None
 1.15A 3eeyC-4jhiA:
undetectable		 3eeyC-4jhiA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_D_SAMD300_0
(PUTATIVE RRNA
METHYLASE)		 4jhi MTN13 PROTEIN
(Medicago
truncatula) 		5 / 12 ASP A 157
ILE A  23
GLY A  27
ASN A 155
LEU A  14
 None
 1.15A 3eeyD-4jhiA:
undetectable		 3eeyD-4jhiA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_E_SAME300_0
(PUTATIVE RRNA
METHYLASE)		 4jhi MTN13 PROTEIN
(Medicago
truncatula) 		5 / 12 ASP A 157
ILE A  23
GLY A  27
ASN A 155
LEU A  14
 None
 1.14A 3eeyE-4jhiA:
undetectable		 3eeyE-4jhiA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_F_SAMF300_0
(PUTATIVE RRNA
METHYLASE)		 4jhi MTN13 PROTEIN
(Medicago
truncatula) 		5 / 12 ASP A 157
ILE A  23
GLY A  27
ASN A 155
LEU A  14
 None
 1.18A 3eeyF-4jhiA:
undetectable		 3eeyF-4jhiA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_H_SAMH300_0
(PUTATIVE RRNA
METHYLASE)		 4jhi MTN13 PROTEIN
(Medicago
truncatula) 		5 / 12 ASP A 157
ILE A  23
GLY A  27
ASN A 155
LEU A  14
 None
 1.17A 3eeyH-4jhiA:
undetectable		 3eeyH-4jhiA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_I_SAMI300_0
(PUTATIVE RRNA
METHYLASE)		 4jhi MTN13 PROTEIN
(Medicago
truncatula) 		5 / 12 ASP A 157
ILE A  23
GLY A  27
ASN A 155
LEU A  14
 None
 1.15A 3eeyI-4jhiA:
undetectable		 3eeyI-4jhiA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_J_SAMJ300_0
(PUTATIVE RRNA
METHYLASE)		 4jhi MTN13 PROTEIN
(Medicago
truncatula) 		5 / 12 ASP A 157
ILE A  23
GLY A  27
ASN A 155
LEU A  14
 None
 1.11A 3eeyJ-4jhiA:
undetectable		 3eeyJ-4jhiA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_C_CHDC150_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 4jhi MTN13 PROTEIN
(Medicago
truncatula) 		5 / 12 THR A 145
VAL A 148
PHE A 141
VAL A  84
TYR A  80
 None
 1.24A 3elzC-4jhiA:
3.2		 3elzC-4jhiA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K9F_F_LFXF0_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B)		 4jhi MTN13 PROTEIN
(Medicago
truncatula) 		4 / 5 SER A  12
ARG A  21
GLY A  22
GLU A  25
 None
 1.19A 3k9fA-4jhiA:
undetectable
3k9fB-4jhiA:
undetectable
3k9fC-4jhiA:
undetectable		 3k9fA-4jhiA:
16.53
3k9fB-4jhiA:
16.53
3k9fC-4jhiA:
24.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_B_TFPB202_2
(PROTEIN S100-A4)		 4jhi MTN13 PROTEIN
(Medicago
truncatula) 		5 / 6 LEU A 152
SER A 150
PHE A 151
ILE A  30
PHE A  38
 None
 1.15A 3ko0B-4jhiA:
undetectable		 3ko0B-4jhiA:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_C_TFPC202_1
(PROTEIN S100-A4)		 4jhi MTN13 PROTEIN
(Medicago
truncatula) 		5 / 11 LEU A 152
SER A 150
PHE A 151
ILE A  30
PHE A  38
 None
 1.19A 3ko0A-4jhiA:
undetectable
3ko0B-4jhiA:
undetectable
3ko0C-4jhiA:
undetectable
3ko0D-4jhiA:
undetectable		 3ko0A-4jhiA:
18.29
3ko0B-4jhiA:
18.29
3ko0C-4jhiA:
18.29
3ko0D-4jhiA:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_D_TFPD202_1
(PROTEIN S100-A4)		 4jhi MTN13 PROTEIN
(Medicago
truncatula) 		5 / 11 LEU A 152
SER A 150
PHE A 151
ILE A  30
PHE A  38
 None
 1.14A 3ko0C-4jhiA:
undetectable
3ko0D-4jhiA:
undetectable
3ko0E-4jhiA:
undetectable
3ko0F-4jhiA:
undetectable		 3ko0C-4jhiA:
18.29
3ko0D-4jhiA:
18.29
3ko0E-4jhiA:
18.29
3ko0F-4jhiA:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_L_TFPL202_1
(PROTEIN S100-A4)		 4jhi MTN13 PROTEIN
(Medicago
truncatula) 		5 / 12 LEU A 152
SER A 150
PHE A 151
ILE A  30
PHE A  38
 None
 1.16A 3ko0K-4jhiA:
undetectable
3ko0L-4jhiA:
undetectable
3ko0M-4jhiA:
undetectable
3ko0N-4jhiA:
undetectable		 3ko0K-4jhiA:
18.29
3ko0L-4jhiA:
18.29
3ko0M-4jhiA:
18.29
3ko0N-4jhiA:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_M_TFPM202_1
(PROTEIN S100-A4)		 4jhi MTN13 PROTEIN
(Medicago
truncatula) 		5 / 12 LEU A 152
SER A 150
PHE A 151
ILE A  30
PHE A  38
 None
 1.12A 3ko0M-4jhiA:
undetectable
3ko0N-4jhiA:
undetectable
3ko0O-4jhiA:
undetectable
3ko0P-4jhiA:
undetectable		 3ko0M-4jhiA:
18.29
3ko0N-4jhiA:
18.29
3ko0O-4jhiA:
18.29
3ko0P-4jhiA:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_O_TFPO202_1
(PROTEIN S100-A4)		 4jhi MTN13 PROTEIN
(Medicago
truncatula) 		5 / 11 LEU A 152
SER A 150
PHE A 151
ILE A  30
PHE A  38
 None
 1.17A 3ko0O-4jhiA:
undetectable
3ko0P-4jhiA:
undetectable
3ko0Q-4jhiA:
undetectable
3ko0R-4jhiA:
undetectable		 3ko0O-4jhiA:
18.29
3ko0P-4jhiA:
18.29
3ko0Q-4jhiA:
18.29
3ko0R-4jhiA:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_P_TFPP202_1
(PROTEIN S100-A4)		 4jhi MTN13 PROTEIN
(Medicago
truncatula) 		5 / 12 LEU A 152
SER A 150
PHE A 151
ILE A  30
PHE A  38
 None
 1.17A 3ko0M-4jhiA:
undetectable
3ko0N-4jhiA:
undetectable
3ko0O-4jhiA:
undetectable
3ko0P-4jhiA:
undetectable		 3ko0M-4jhiA:
18.29
3ko0N-4jhiA:
18.29
3ko0O-4jhiA:
18.29
3ko0P-4jhiA:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_S_TFPS202_1
(PROTEIN S100-A4)		 4jhi MTN13 PROTEIN
(Medicago
truncatula) 		4 / 6 LEU A 152
PHE A 151
ILE A  30
PHE A  38
 None
 1.01A 3ko0S-4jhiA:
undetectable		 3ko0S-4jhiA:
18.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4A84_A_DXCA1160_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 4jhi MTN13 PROTEIN
(Medicago
truncatula) 		5 / 12 TYR A  80
TYR A  82
VAL A  84
ILE A  98
TYR A 120
 None
EMU  A 202 (-4.9A)
None
EMU  A 202 ( 4.9A)
None
 0.74A 4a84A-4jhiA:
20.3		 4a84A-4jhiA:
42.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EQ4_A_SALA601_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 4jhi MTN13 PROTEIN
(Medicago
truncatula) 		4 / 7 LEU A  90
TYR A 133
ILE A  98
GLY A  87
 None
EMU  A 202 ( 4.3A)
EMU  A 202 ( 4.9A)
None
 0.94A 4eq4A-4jhiA:
undetectable		 4eq4A-4jhiA:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EQ4_B_SALB601_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 4jhi MTN13 PROTEIN
(Medicago
truncatula) 		4 / 8 LEU A  90
TYR A 133
ILE A  98
GLY A  87
 None
EMU  A 202 ( 4.3A)
EMU  A 202 ( 4.9A)
None
 0.94A 4eq4B-4jhiA:
undetectable		 4eq4B-4jhiA:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EQL_A_SALA602_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 4jhi MTN13 PROTEIN
(Medicago
truncatula) 		4 / 7 LEU A  90
TYR A 133
ILE A  98
GLY A  87
 None
EMU  A 202 ( 4.3A)
EMU  A 202 ( 4.9A)
None
 0.91A 4eqlA-4jhiA:
undetectable		 4eqlA-4jhiA:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EQL_B_SALB602_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 4jhi MTN13 PROTEIN
(Medicago
truncatula) 		4 / 7 LEU A  90
TYR A 133
ILE A  98
GLY A  87
 None
EMU  A 202 ( 4.3A)
EMU  A 202 ( 4.9A)
None
 0.93A 4eqlB-4jhiA:
undetectable		 4eqlB-4jhiA:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L39_A_SALA602_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 4jhi MTN13 PROTEIN
(Medicago
truncatula) 		4 / 6 LEU A  90
TYR A 133
ILE A  98
GLY A  87
 None
EMU  A 202 ( 4.3A)
EMU  A 202 ( 4.9A)
None
 0.90A 4l39A-4jhiA:
undetectable		 4l39A-4jhiA:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L39_B_SALB601_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 4jhi MTN13 PROTEIN
(Medicago
truncatula) 		4 / 7 LEU A  90
TYR A 133
ILE A  98
GLY A  87
 None
EMU  A 202 ( 4.3A)
EMU  A 202 ( 4.9A)
None
 0.82A 4l39B-4jhiA:
undetectable		 4l39B-4jhiA:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MXB_A_ML1A222_1
(CLASS 10 PLANT
PATHOGENESIS-RELATED
PROTEIN)		 4jhi MTN13 PROTEIN
(Medicago
truncatula) 		5 / 10 ILE A  39
LEU A  57
TYR A  82
ARG A 140
GLY A 143
 None
None
EMU  A 202 (-4.9A)
None
None
 1.09A 5mxbA-4jhiA:
20.0		 5mxbA-4jhiA:
28.66