SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4jhj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WOP_A_FFOA2887_1
(AMINOMETHYLTRANSFERA
SE)		 4jhj MIF4G
DOMAIN-CONTAINING
PROTEIN B
(Danio
rerio) 		3 / 3 ASP A 160
GLU A 197
ARG A 178
 None
 0.81A 1wopA-4jhjA:
undetectable		 1wopA-4jhjA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J7X_A_ESTA1454_1
(ESTROGEN RECEPTOR
BETA)		 4jhj MIF4G
DOMAIN-CONTAINING
PROTEIN B
(Danio
rerio) 		5 / 12 GLU A 147
LEU A 136
LEU A 142
ILE A 198
HIS A 156
 None
 1.27A 2j7xA-4jhjA:
undetectable		 2j7xA-4jhjA:
24.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TGV_B_BEZB160_0
(HEME-BINDING PROTEIN
HUTZ)		 4jhj MIF4G
DOMAIN-CONTAINING
PROTEIN B
(Danio
rerio) 		4 / 4 LEU A 155
GLY A 159
LEU A 162
GLU A 163
 None
 0.86A 3tgvB-4jhjA:
undetectable		 3tgvB-4jhjA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J24_C_ESTC600_1
(ESTROGEN RECEPTOR
BETA)		 4jhj MIF4G
DOMAIN-CONTAINING
PROTEIN B
(Danio
rerio) 		5 / 12 GLU A 147
LEU A 136
LEU A 142
ILE A 198
HIS A 156
 None
 1.31A 4j24C-4jhjA:
undetectable		 4j24C-4jhjA:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J26_A_ESTA600_1
(ESTROGEN RECEPTOR
BETA)		 4jhj MIF4G
DOMAIN-CONTAINING
PROTEIN B
(Danio
rerio) 		5 / 12 GLU A 147
LEU A 136
LEU A 142
ILE A 198
HIS A 156
 None
 1.29A 4j26A-4jhjA:
undetectable		 4j26A-4jhjA:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J26_B_ESTB600_1
(ESTROGEN RECEPTOR
BETA)		 4jhj MIF4G
DOMAIN-CONTAINING
PROTEIN B
(Danio
rerio) 		5 / 12 GLU A 147
LEU A 136
LEU A 142
ILE A 198
HIS A 156
 None
 1.29A 4j26B-4jhjA:
undetectable		 4j26B-4jhjA:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMC_A_29JA604_1
(TRANSPORTER)		 4jhj MIF4G
DOMAIN-CONTAINING
PROTEIN B
(Danio
rerio) 		4 / 7 ARG A  57
ILE A  41
PHE A  51
LEU A  22
 None
 0.89A 4mmcA-4jhjA:
undetectable		 4mmcA-4jhjA:
16.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UXQ_A_0LIA1752_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 4)		 4jhj MIF4G
DOMAIN-CONTAINING
PROTEIN B
(Danio
rerio) 		4 / 7 MET A 122
ILE A 111
ALA A  55
ILE A 108
 None
 0.66A 4uxqA-4jhjA:
undetectable		 4uxqA-4jhjA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWV_A_ACAA18_1
(SCRFP-TAG,GP41)		 4jhj MIF4G
DOMAIN-CONTAINING
PROTEIN B
(Danio
rerio) 		5 / 12 LYS A 143
ASN A 144
GLU A 145
GLU A 147
LEU A 151
 None
 1.19A 5nwvA-4jhjA:
undetectable		 5nwvA-4jhjA:
9.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TOA_B_ESTB601_1
(ESTROGEN RECEPTOR
BETA)		 4jhj MIF4G
DOMAIN-CONTAINING
PROTEIN B
(Danio
rerio) 		5 / 12 GLU A 147
LEU A 136
ILE A 198
LEU A 177
HIS A 156
 None
 1.16A 5toaB-4jhjA:
undetectable		 5toaB-4jhjA:
24.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_I_PCFI101_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL
CYTOCHROME B-C1
COMPLEX SUBUNIT 9
CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL)		 4jhj MIF4G
DOMAIN-CONTAINING
PROTEIN B
(Danio
rerio) 		5 / 11 SER A  39
VAL A  32
GLY A  30
ASN A  78
VAL A  74
 None
 1.41A 6hu9A-4jhjA:
undetectable
6hu9E-4jhjA:
undetectable
6hu9I-4jhjA:
undetectable		 6hu9A-4jhjA:
19.40
6hu9E-4jhjA:
20.98
6hu9I-4jhjA:
18.02