SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4jhm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DHF_A_FOLA187_0
(DIHYDROFOLATE
REDUCTASE)
4jhm MANDELATE RACEMASE /
MUCONATE LACTONIZING
ENZYME, C-TERMINAL
DOMAIN PROTEIN

(Pseudovibrio
sp.
JE062)
5 / 12 ILE A 107
ALA A  51
ILE A  71
LEU A  90
THR A 304
None
1.19A 1dhfA-4jhmA:
undetectable
1dhfA-4jhmA:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DHF_B_FOLB187_0
(DIHYDROFOLATE
REDUCTASE)
4jhm MANDELATE RACEMASE /
MUCONATE LACTONIZING
ENZYME, C-TERMINAL
DOMAIN PROTEIN

(Pseudovibrio
sp.
JE062)
5 / 12 ILE A 107
ALA A  51
ILE A  71
LEU A  90
THR A 304
None
1.19A 1dhfB-4jhmA:
undetectable
1dhfB-4jhmA:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LIN_A_TFPA155_1
(CALMODULIN)
4jhm MANDELATE RACEMASE /
MUCONATE LACTONIZING
ENZYME, C-TERMINAL
DOMAIN PROTEIN

(Pseudovibrio
sp.
JE062)
4 / 7 GLN A 297
GLU A 322
PHE A 141
ALA A 196
None
1.26A 1linA-4jhmA:
undetectable
1linA-4jhmA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OT7_A_CHCA1001_1
(BILE ACID RECEPTOR)
4jhm MANDELATE RACEMASE /
MUCONATE LACTONIZING
ENZYME, C-TERMINAL
DOMAIN PROTEIN

(Pseudovibrio
sp.
JE062)
5 / 12 PHE A 159
SER A 134
PHE A 321
ILE A 338
HIS A 157
None
1.38A 1ot7A-4jhmA:
undetectable
1ot7A-4jhmA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OT7_A_CHCA1001_1
(BILE ACID RECEPTOR)
4jhm MANDELATE RACEMASE /
MUCONATE LACTONIZING
ENZYME, C-TERMINAL
DOMAIN PROTEIN

(Pseudovibrio
sp.
JE062)
5 / 12 SER A 134
ILE A 132
PHE A 321
ILE A 338
HIS A 157
None
1.41A 1ot7A-4jhmA:
undetectable
1ot7A-4jhmA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IGT_C_SAMC1003_1
(SAM DEPENDENT
METHYLTRANSFERASE)
4jhm MANDELATE RACEMASE /
MUCONATE LACTONIZING
ENZYME, C-TERMINAL
DOMAIN PROTEIN

(Pseudovibrio
sp.
JE062)
4 / 4 ASP A 173
ASP A 194
ASP A  26
GLY A 197
None
1.43A 2igtC-4jhmA:
undetectable
2igtC-4jhmA:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZIF_B_SAMB298_0
(PUTATIVE
MODIFICATION
METHYLASE)
4jhm MANDELATE RACEMASE /
MUCONATE LACTONIZING
ENZYME, C-TERMINAL
DOMAIN PROTEIN

(Pseudovibrio
sp.
JE062)
5 / 12 ALA A 329
ALA A 306
PHE A 321
PHE A 330
LEU A 332
None
1.17A 2zifB-4jhmA:
undetectable
2zifB-4jhmA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A35_A_RBFA191_1
(LUMAZINE PROTEIN)
4jhm MANDELATE RACEMASE /
MUCONATE LACTONIZING
ENZYME, C-TERMINAL
DOMAIN PROTEIN

(Pseudovibrio
sp.
JE062)
5 / 12 LEU A  40
ASP A 111
ALA A 109
THR A  83
ASN A  79
None
1.09A 3a35A-4jhmA:
undetectable
3a35A-4jhmA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A35_B_RBFB191_1
(LUMAZINE PROTEIN)
4jhm MANDELATE RACEMASE /
MUCONATE LACTONIZING
ENZYME, C-TERMINAL
DOMAIN PROTEIN

(Pseudovibrio
sp.
JE062)
5 / 12 LEU A  40
ASP A 111
ALA A 109
THR A  83
ASN A  79
None
1.03A 3a35B-4jhmA:
undetectable
3a35B-4jhmA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A3B_A_RBFA191_1
(LUMAZINE PROTEIN)
4jhm MANDELATE RACEMASE /
MUCONATE LACTONIZING
ENZYME, C-TERMINAL
DOMAIN PROTEIN

(Pseudovibrio
sp.
JE062)
5 / 12 LEU A  40
ASP A 111
ALA A 109
THR A  83
ASN A  79
None
1.08A 3a3bA-4jhmA:
undetectable
3a3bA-4jhmA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E9X_A_NIMA1_1
(LACTOTRANSFERRIN')
4jhm MANDELATE RACEMASE /
MUCONATE LACTONIZING
ENZYME, C-TERMINAL
DOMAIN PROTEIN

(Pseudovibrio
sp.
JE062)
4 / 4 GLU A  43
GLY A  45
THR A  46
GLU A  47
None
1.22A 3e9xA-4jhmA:
undetectable
3e9xA-4jhmA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ID5_B_SAMB301_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)
4jhm MANDELATE RACEMASE /
MUCONATE LACTONIZING
ENZYME, C-TERMINAL
DOMAIN PROTEIN

(Pseudovibrio
sp.
JE062)
5 / 11 LYS A 115
ASP A 270
ALA A 271
ASP A 111
ILE A 107
None
1.29A 3id5B-4jhmA:
undetectable
3id5B-4jhmA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ID5_F_SAMF301_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)
4jhm MANDELATE RACEMASE /
MUCONATE LACTONIZING
ENZYME, C-TERMINAL
DOMAIN PROTEIN

(Pseudovibrio
sp.
JE062)
5 / 11 LYS A 115
ASP A 270
ALA A 271
ASP A 111
ILE A 107
None
1.29A 3id5F-4jhmA:
undetectable
3id5F-4jhmA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W68_A_VIVA301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)
4jhm MANDELATE RACEMASE /
MUCONATE LACTONIZING
ENZYME, C-TERMINAL
DOMAIN PROTEIN

(Pseudovibrio
sp.
JE062)
5 / 12 VAL A 356
SER A 334
ILE A  37
VAL A 363
LEU A  14
None
1.09A 3w68A-4jhmA:
1.9
3w68A-4jhmA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_A_ACTA506_0
(RNA POLYMERASE
3D-POL)
4jhm MANDELATE RACEMASE /
MUCONATE LACTONIZING
ENZYME, C-TERMINAL
DOMAIN PROTEIN

(Pseudovibrio
sp.
JE062)
3 / 3 VAL A 273
GLY A 275
LYS A 102
None
0.58A 4k50A-4jhmA:
undetectable
4k50A-4jhmA:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_E_ACTE504_0
(RNA POLYMERASE
3D-POL)
4jhm MANDELATE RACEMASE /
MUCONATE LACTONIZING
ENZYME, C-TERMINAL
DOMAIN PROTEIN

(Pseudovibrio
sp.
JE062)
3 / 3 VAL A 273
GLY A 275
LYS A 102
None
0.68A 4k50E-4jhmA:
undetectable
4k50E-4jhmA:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_I_ACTI504_0
(RNA POLYMERASE
3D-POL)
4jhm MANDELATE RACEMASE /
MUCONATE LACTONIZING
ENZYME, C-TERMINAL
DOMAIN PROTEIN

(Pseudovibrio
sp.
JE062)
3 / 3 VAL A 273
GLY A 275
LYS A 102
None
0.58A 4k50I-4jhmA:
undetectable
4k50I-4jhmA:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZT_C_RTLC201_0
(RETINOL-BINDING
PROTEIN 2)
4jhm MANDELATE RACEMASE /
MUCONATE LACTONIZING
ENZYME, C-TERMINAL
DOMAIN PROTEIN

(Pseudovibrio
sp.
JE062)
5 / 12 ILE A   6
ALA A 108
THR A  95
LEU A  75
LEU A  11
None
1.36A 4qztC-4jhmA:
undetectable
4qztC-4jhmA:
15.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_C_RBFC201_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)
4jhm MANDELATE RACEMASE /
MUCONATE LACTONIZING
ENZYME, C-TERMINAL
DOMAIN PROTEIN

(Pseudovibrio
sp.
JE062)
5 / 9 LEU A  11
VAL A 363
LEU A  14
ILE A  37
PHE A  60
None
1.16A 4r38C-4jhmA:
undetectable
4r38C-4jhmA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XE0_A_40LA1101_0
(PHOSPHATIDYLINOSITOL
4,5-BISPHOSPHATE
3-KINASE CATALYTIC
SUBUNIT DELTA
ISOFORM)
4jhm MANDELATE RACEMASE /
MUCONATE LACTONIZING
ENZYME, C-TERMINAL
DOMAIN PROTEIN

(Pseudovibrio
sp.
JE062)
5 / 12 ILE A  64
VAL A  38
ASP A 106
ASN A  87
ILE A  71
None
1.23A 4xe0A-4jhmA:
undetectable
4xe0A-4jhmA:
16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECL_A_ILEA602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)
4jhm MANDELATE RACEMASE /
MUCONATE LACTONIZING
ENZYME, C-TERMINAL
DOMAIN PROTEIN

(Pseudovibrio
sp.
JE062)
4 / 6 ALA A 196
THR A 195
TYR A 199
HIS A 165
None
0.91A 5eclA-4jhmA:
0.3
5eclA-4jhmA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_K_BO2K305_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-1)
4jhm MANDELATE RACEMASE /
MUCONATE LACTONIZING
ENZYME, C-TERMINAL
DOMAIN PROTEIN

(Pseudovibrio
sp.
JE062)
5 / 11 THR A  52
ALA A  51
GLY A 275
GLY A 276
ALA A 271
None
0.65A 5lf3K-4jhmA:
undetectable
5lf3L-4jhmA:
undetectable
5lf3K-4jhmA:
17.53
5lf3L-4jhmA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_Y_BO2Y305_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-1)
4jhm MANDELATE RACEMASE /
MUCONATE LACTONIZING
ENZYME, C-TERMINAL
DOMAIN PROTEIN

(Pseudovibrio
sp.
JE062)
5 / 11 THR A  52
ALA A  51
GLY A 275
GLY A 276
ALA A 271
None
0.65A 5lf3Y-4jhmA:
undetectable
5lf3Z-4jhmA:
undetectable
5lf3Y-4jhmA:
17.53
5lf3Z-4jhmA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_K_6V8K305_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-5)
4jhm MANDELATE RACEMASE /
MUCONATE LACTONIZING
ENZYME, C-TERMINAL
DOMAIN PROTEIN

(Pseudovibrio
sp.
JE062)
5 / 11 THR A  52
ALA A  51
GLY A 275
GLY A 276
ALA A 271
None
0.58A 5lf7K-4jhmA:
undetectable
5lf7L-4jhmA:
undetectable
5lf7K-4jhmA:
17.53
5lf7L-4jhmA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_Y_6V8Y306_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-5)
4jhm MANDELATE RACEMASE /
MUCONATE LACTONIZING
ENZYME, C-TERMINAL
DOMAIN PROTEIN

(Pseudovibrio
sp.
JE062)
5 / 11 THR A  52
ALA A  51
GLY A 275
GLY A 276
ALA A 271
None
0.58A 5lf7Y-4jhmA:
undetectable
5lf7Z-4jhmA:
undetectable
5lf7Y-4jhmA:
17.53
5lf7Z-4jhmA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M66_D_ADND502_2
(ADENOSYLHOMOCYSTEINA
SE)
4jhm MANDELATE RACEMASE /
MUCONATE LACTONIZING
ENZYME, C-TERMINAL
DOMAIN PROTEIN

(Pseudovibrio
sp.
JE062)
3 / 3 THR A  46
THR A  83
LEU A 121
None
0.65A 5m66D-4jhmA:
undetectable
5m66D-4jhmA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D9K_F_ACTF802_0
(UNCHARACTERIZED
PROTEIN)
4jhm MANDELATE RACEMASE /
MUCONATE LACTONIZING
ENZYME, C-TERMINAL
DOMAIN PROTEIN

(Pseudovibrio
sp.
JE062)
3 / 3 TYR A 301
ALA A 333
LEU A  14
None
0.72A 6d9kF-4jhmA:
undetectable
6d9kF-4jhmA:
19.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_K_BO2K301_0
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
4jhm MANDELATE RACEMASE /
MUCONATE LACTONIZING
ENZYME, C-TERMINAL
DOMAIN PROTEIN

(Pseudovibrio
sp.
JE062)
5 / 11 THR A  52
ALA A  51
GLY A 275
GLY A 276
ALA A 271
None
0.66A 6hwdK-4jhmA:
undetectable
6hwdL-4jhmA:
undetectable
6hwdK-4jhmA:
13.54
6hwdL-4jhmA:
11.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_Y_BO2Y301_0
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
4jhm MANDELATE RACEMASE /
MUCONATE LACTONIZING
ENZYME, C-TERMINAL
DOMAIN PROTEIN

(Pseudovibrio
sp.
JE062)
5 / 11 THR A  52
ALA A  51
GLY A 275
GLY A 276
ALA A 271
None
0.65A 6hwdY-4jhmA:
undetectable
6hwdZ-4jhmA:
undetectable
6hwdY-4jhmA:
13.54
6hwdZ-4jhmA:
11.98