SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4jhy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EII_A_RTLA135_0
(CELLULAR
RETINOL-BINDING
PROTEIN II)		 4jhy HYPOTHETICAL PROTEIN
(Parabacteroides
distasonis) 		5 / 12 ALA A 137
ILE A 115
PHE A 159
LEU A 170
LEU A  90
 None
 1.38A 1eiiA-4jhyA:
undetectable		 1eiiA-4jhyA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_C_DVAC6_0
(GRAMICIDIN D)		 4jhy HYPOTHETICAL PROTEIN
(Parabacteroides
distasonis) 		3 / 3 ALA A 172
VAL A 174
TRP A  59
 None
 0.87A 1w5uC-4jhyA:
undetectable
1w5uD-4jhyA:
undetectable		 1w5uC-4jhyA:
6.25
1w5uD-4jhyA:
6.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_C_DVAC6_0
(GRAMICIDIN D)		 4jhy HYPOTHETICAL PROTEIN
(Parabacteroides
distasonis) 		3 / 3 ALA A 172
VAL A 174
TRP A  59
 None
 0.82A 3l8lC-4jhyA:
undetectable
3l8lD-4jhyA:
undetectable		 3l8lC-4jhyA:
6.25
3l8lD-4jhyA:
6.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AFG_C_QMRC1214_1
(CAPITELLA TELETA
ACHBP)		 4jhy HYPOTHETICAL PROTEIN
(Parabacteroides
distasonis) 		4 / 8 VAL A 174
CYH A 108
ILE A 115
ILE A  82
 None
 1.03A 4afgD-4jhyA:
undetectable
4afgE-4jhyA:
undetectable		 4afgD-4jhyA:
19.41
4afgE-4jhyA:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_A_ADNA402_1
(PROBABLE SUGAR
KINASE PROTEIN)		 4jhy HYPOTHETICAL PROTEIN
(Parabacteroides
distasonis) 		5 / 10 THR A  47
ILE A  82
ALA A 178
ALA A  55
ILE A  56
 None
 1.02A 4lbgA-4jhyA:
undetectable		 4lbgA-4jhyA:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4S0V_A_SUVA2001_2
(HUMAN OREXIN
RECEPTOR TYPE 2
FUSION PROTEIN TO P.
ABYSII GLYCOGEN
SYNTHASE)		 4jhy HYPOTHETICAL PROTEIN
(Parabacteroides
distasonis) 		4 / 5 ILE A 153
PRO A 156
TYR A  38
VAL A  36
 None
 1.13A 4s0vA-4jhyA:
undetectable		 4s0vA-4jhyA:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D75_A_FK5A301_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP3)		 4jhy HYPOTHETICAL PROTEIN
(Parabacteroides
distasonis) 		5 / 11 ASP A 173
ILE A 115
TYR A 113
ALA A 177
ILE A  56
 None
 1.21A 5d75A-4jhyA:
undetectable		 5d75A-4jhyA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KB6_A_ADNA401_1
(ADENOSINE KINASE)		 4jhy HYPOTHETICAL PROTEIN
(Parabacteroides
distasonis) 		5 / 12 THR A  47
ILE A 106
ALA A 178
ALA A  55
ILE A  56
 None
 0.89A 5kb6A-4jhyA:
undetectable		 5kb6A-4jhyA:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KB6_B_ADNB401_1
(ADENOSINE KINASE)		 4jhy HYPOTHETICAL PROTEIN
(Parabacteroides
distasonis) 		5 / 12 THR A  47
ILE A 106
ALA A 178
ALA A  55
ILE A  56
 None
 0.87A 5kb6B-4jhyA:
undetectable		 5kb6B-4jhyA:
18.23