SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4jif'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OQ5_A_CELA701_2
(CARBONIC ANHYDRASE
II)		 4jif INTEGRIN
BETA-1-BINDING
PROTEIN 1
(Homo
sapiens) 		4 / 4 HIS A 131
VAL A 121
THR A 159
LEU A 135
 None
 1.50A 1oq5A-4jifA:
undetectable		 1oq5A-4jifA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KI6_A_IPHA901_0
(PROTEIN ARGONAUTE-2)		 4jif INTEGRIN
BETA-1-BINDING
PROTEIN 1
(Homo
sapiens) 		4 / 5 LEU A 169
TYR A 167
LEU A  88
TYR A  91
 None
 1.39A 5ki6A-4jifA:
undetectable		 5ki6A-4jifA:
10.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OM3_B_DXTB501_1
(ALPHA-1-ANTICHYMOTRY
PSIN)		 4jif INTEGRIN
BETA-1-BINDING
PROTEIN 1
(Homo
sapiens) 		4 / 6 LEU A 187
SER A 188
PHE A 191
ASP A 192
 None
 0.55A 5om3A-4jifA:
undetectable
5om3B-4jifA:
undetectable		 5om3A-4jifA:
18.83
5om3B-4jifA:
14.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YCP_A_BRLA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 4jif INTEGRIN
BETA-1-BINDING
PROTEIN 1
KREV INTERACTION
TRAPPED PROTEIN 1
(Homo
sapiens;
Homo
sapiens) 		3 / 3 GLY A 118
VAL B 190
MET A 141
 None
 0.57A 5ycpA-4jifA:
undetectable		 5ycpA-4jifA:
19.62