SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4jip'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_A_BEZA1162_0
(PEROXIREDOXIN 5)		 4jip GTN REDUCTASE
(Agrobacterium
tumefaciens) 		5 / 10 THR A  56
PRO A  69
GLY A  70
PHE A 172
GLY A  79
 None
 1.23A 1h4oA-4jipA:
undetectable
1h4oB-4jipA:
undetectable		 1h4oA-4jipA:
19.79
1h4oB-4jipA:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_C_BEZC1162_0
(PEROXIREDOXIN 5)		 4jip GTN REDUCTASE
(Agrobacterium
tumefaciens) 		5 / 9 THR A  56
PRO A  69
GLY A  70
PHE A 172
GLY A  79
 None
 1.27A 1h4oC-4jipA:
undetectable
1h4oD-4jipA:
undetectable		 1h4oC-4jipA:
19.79
1h4oD-4jipA:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_E_BEZE1162_0
(PEROXIREDOXIN 5)		 4jip GTN REDUCTASE
(Agrobacterium
tumefaciens) 		5 / 9 THR A  56
PRO A  69
GLY A  70
PHE A 172
GLY A  79
 None
 1.27A 1h4oE-4jipA:
undetectable
1h4oF-4jipA:
undetectable		 1h4oE-4jipA:
19.79
1h4oF-4jipA:
19.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1H60_A_STRA500_1
(PENTAERYTHRITOL
TETRANITRATE
REDUCTASE)		 4jip GTN REDUCTASE
(Agrobacterium
tumefaciens) 		5 / 9 THR A  25
TYR A  65
HIS A 178
TYR A 183
TYR A 356
 FMN  A 401 ( 3.6A)
None
FMN  A 401 ( 3.6A)
HBA  A 402 (-4.3A)
FMN  A 401 ( 4.2A)
 0.22A 1h60A-4jipA:
56.8		 1h60A-4jipA:
49.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NR6_A_DIFA501_1
(CYTOCHROME P450 2C5)		 4jip GTN REDUCTASE
(Agrobacterium
tumefaciens) 		5 / 9 LEU A   4
GLY A  49
ALA A  48
LEU A 337
PHE A 327
 None
 1.14A 1nr6A-4jipA:
undetectable		 1nr6A-4jipA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S8F_B_BEZB1503_0
(RAS-RELATED PROTEIN
RAB-9A)		 4jip GTN REDUCTASE
(Agrobacterium
tumefaciens) 		4 / 6 GLU A 213
LEU A 211
ARG A 209
PHE A 188
 None
 1.13A 1s8fB-4jipA:
undetectable		 1s8fB-4jipA:
18.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ABA_A_STRA1500_1
(PENTAERYTHRITOL
TETRANITRATE
REDUCTASE)		 4jip GTN REDUCTASE
(Agrobacterium
tumefaciens) 		5 / 9 THR A  25
TYR A  65
HIS A 178
TYR A 183
TYR A 356
 FMN  A 401 ( 3.6A)
None
FMN  A 401 ( 3.6A)
HBA  A 402 (-4.3A)
FMN  A 401 ( 4.2A)
 0.22A 2abaA-4jipA:
57.0		 2abaA-4jipA:
49.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXF_B_DZPB2001_1
(SERUM ALBUMIN)		 4jip GTN REDUCTASE
(Agrobacterium
tumefaciens) 		5 / 12 ILE A 229
PHE A 289
LEU A 248
VAL A 252
LEU A 189
 None
 1.26A 2bxfB-4jipA:
undetectable		 2bxfB-4jipA:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UXO_B_TACB1211_1
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR TTGR)		 4jip GTN REDUCTASE
(Agrobacterium
tumefaciens) 		5 / 11 LEU A 256
LEU A 231
ILE A  13
VAL A 175
ILE A 177
 None
 1.20A 2uxoB-4jipA:
0.3		 2uxoB-4jipA:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0Z_O_C41O1327_2
(RENIN)		 4jip GTN REDUCTASE
(Agrobacterium
tumefaciens) 		4 / 8 SER A 192
THR A 193
PRO A 119
LEU A 184
 None
 1.19A 2v0zO-4jipA:
undetectable		 2v0zO-4jipA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VL2_A_BEZA1162_0
(PEROXIREDOXIN-5)		 4jip GTN REDUCTASE
(Agrobacterium
tumefaciens) 		5 / 10 THR A  56
PRO A  69
GLY A  70
PHE A 172
GLY A  79
 None
 1.22A 2vl2A-4jipA:
undetectable
2vl2C-4jipA:
undetectable		 2vl2A-4jipA:
20.05
2vl2C-4jipA:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XFS_B_J01B600_1
(ORF12)		 4jip GTN REDUCTASE
(Agrobacterium
tumefaciens) 		5 / 11 ALA A 164
ALA A 166
GLY A 163
SER A 162
ARG A  74
 None
 1.24A 2xfsB-4jipA:
undetectable		 2xfsB-4jipA:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_A_TRPA1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 4jip GTN REDUCTASE
(Agrobacterium
tumefaciens) 		5 / 10 GLY A  62
GLN A  60
ASP A 159
ILE A 156
VAL A 117
 None
 1.15A 3fhjA-4jipA:
undetectable		 3fhjA-4jipA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_C_TRPC1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 4jip GTN REDUCTASE
(Agrobacterium
tumefaciens) 		5 / 10 GLY A  62
GLN A  60
ASP A 159
ILE A 156
VAL A 117
 None
 1.19A 3fhjC-4jipA:
undetectable		 3fhjC-4jipA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_E_TRPE1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 4jip GTN REDUCTASE
(Agrobacterium
tumefaciens) 		5 / 10 GLY A  62
GLN A  60
ASP A 159
ILE A 156
VAL A 117
 None
 1.14A 3fhjE-4jipA:
2.1		 3fhjE-4jipA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_A_TRPA1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 4jip GTN REDUCTASE
(Agrobacterium
tumefaciens) 		5 / 9 GLY A  62
GLN A  60
ASP A 159
ILE A 156
VAL A 117
 None
 1.19A 3fi0A-4jipA:
undetectable		 3fi0A-4jipA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_K_TRPK1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 4jip GTN REDUCTASE
(Agrobacterium
tumefaciens) 		5 / 9 GLY A  62
GLN A  60
ASP A 159
ILE A 156
VAL A 117
 None
 1.20A 3fi0K-4jipA:
undetectable		 3fi0K-4jipA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_L_TRPL1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 4jip GTN REDUCTASE
(Agrobacterium
tumefaciens) 		5 / 9 GLY A  62
GLN A  60
ASP A 159
ILE A 156
VAL A 117
 None
 1.12A 3fi0L-4jipA:
undetectable		 3fi0L-4jipA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_M_TRPM1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 4jip GTN REDUCTASE
(Agrobacterium
tumefaciens) 		5 / 9 GLY A  62
GLN A  60
ASP A 159
ILE A 156
VAL A 117
 None
 1.18A 3fi0M-4jipA:
undetectable		 3fi0M-4jipA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_N_TRPN1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 4jip GTN REDUCTASE
(Agrobacterium
tumefaciens) 		5 / 9 GLY A  62
GLN A  60
ASP A 159
ILE A 156
VAL A 117
 None
 1.19A 3fi0N-4jipA:
2.2		 3fi0N-4jipA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_O_TRPO1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 4jip GTN REDUCTASE
(Agrobacterium
tumefaciens) 		5 / 9 GLY A  62
GLN A  60
ASP A 159
ILE A 156
VAL A 117
 None
 1.16A 3fi0O-4jipA:
undetectable		 3fi0O-4jipA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_R_TRPR1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 4jip GTN REDUCTASE
(Agrobacterium
tumefaciens) 		5 / 9 GLY A  62
GLN A  60
ASP A 159
ILE A 156
VAL A 117
 None
 1.18A 3fi0R-4jipA:
undetectable		 3fi0R-4jipA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXC_A_ROCA401_2
(PROTEASE)		 4jip GTN REDUCTASE
(Agrobacterium
tumefaciens) 		3 / 3 ARG A 226
LEU A 168
THR A  84
 None
 0.84A 3oxcA-4jipA:
undetectable		 3oxcA-4jipA:
13.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_B_WPPB400_2
(BETA-LACTAMASE)		 4jip GTN REDUCTASE
(Agrobacterium
tumefaciens) 		4 / 5 TYR A 363
PRO A 335
THR A  47
THR A  53
 None
 1.26A 3q07B-4jipA:
undetectable		 3q07B-4jipA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9T_B_BEZB264_0
(ECHA1_1)		 4jip GTN REDUCTASE
(Agrobacterium
tumefaciens) 		4 / 7 ILE A 264
GLU A 176
ALA A 179
ALA A 180
 None
 0.90A 3r9tB-4jipA:
2.1		 3r9tB-4jipA:
24.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S53_A_017A201_1
(PROTEASE)		 4jip GTN REDUCTASE
(Agrobacterium
tumefaciens) 		5 / 9 GLY A 223
ALA A 224
GLY A  11
ILE A  13
ILE A 229
 None
 0.94A 3s53A-4jipA:
undetectable		 3s53A-4jipA:
13.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4A3U_A_ACTA1358_0
(NADH:FLAVIN
OXIDOREDUCTASE/NADH
OXIDASE)		 4jip GTN REDUCTASE
(Agrobacterium
tumefaciens) 		5 / 9 ALA A  22
PRO A  23
GLN A  97
ARG A 230
ASN A 305
 FMN  A 401 (-3.4A)
FMN  A 401 (-3.9A)
FMN  A 401 (-2.9A)
FMN  A 401 (-3.0A)
FMN  A 401 (-3.1A)
 1.31A 4a3uA-4jipA:
55.0		 4a3uA-4jipA:
43.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4A3U_A_NCAA1359_0
(NADH:FLAVIN
OXIDOREDUCTASE/NADH
OXIDASE)		 4jip GTN REDUCTASE
(Agrobacterium
tumefaciens) 		6 / 7 THR A  25
TRP A  99
HIS A 178
ASN A 181
TYR A 183
TYR A 356
 FMN  A 401 ( 3.6A)
None
FMN  A 401 ( 3.6A)
HBA  A 402 ( 3.8A)
HBA  A 402 (-4.3A)
FMN  A 401 ( 4.2A)
 0.42A 4a3uA-4jipA:
55.0		 4a3uA-4jipA:
43.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4A3U_B_NCAB1359_0
(NADH:FLAVIN
OXIDOREDUCTASE/NADH
OXIDASE)		 4jip GTN REDUCTASE
(Agrobacterium
tumefaciens) 		6 / 7 THR A  25
TRP A  99
HIS A 178
ASN A 181
TYR A 183
TYR A 356
 FMN  A 401 ( 3.6A)
None
FMN  A 401 ( 3.6A)
HBA  A 402 ( 3.8A)
HBA  A 402 (-4.3A)
FMN  A 401 ( 4.2A)
 0.42A 4a3uB-4jipA:
55.1		 4a3uB-4jipA:
43.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4AWU_A_4CHA502_0
(OXIDOREDUCTASE,
FMN-BINDING)		 4jip GTN REDUCTASE
(Agrobacterium
tumefaciens) 		5 / 7 THR A  25
TRP A  99
HIS A 178
ASN A 181
TYR A 183
 FMN  A 401 ( 3.6A)
None
FMN  A 401 ( 3.6A)
HBA  A 402 ( 3.8A)
HBA  A 402 (-4.3A)
 0.21A 4awuA-4jipA:
56.7		 4awuA-4jipA:
45.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DF2_A_4CHA506_0
(NADPH DEHYDROGENASE)		 4jip GTN REDUCTASE
(Agrobacterium
tumefaciens) 		5 / 6 THR A  25
TYR A  65
HIS A 178
TYR A 183
TYR A 356
 FMN  A 401 ( 3.6A)
None
FMN  A 401 ( 3.6A)
HBA  A 402 (-4.3A)
FMN  A 401 ( 4.2A)
 0.77A 4df2A-4jipA:
46.7		 4df2A-4jipA:
34.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGZ_A_CQAA302_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 4jip GTN REDUCTASE
(Agrobacterium
tumefaciens) 		4 / 7 GLU A 242
GLU A 186
GLY A 201
ARG A 207
 None
 0.95A 4fgzA-4jipA:
undetectable		 4fgzA-4jipA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GC9_A_ACTA402_0
(DIMETHYLADENOSINE
TRANSFERASE 1,
MITOCHONDRIAL)		 4jip GTN REDUCTASE
(Agrobacterium
tumefaciens) 		3 / 3 LYS A 290
TYR A 293
ARG A 294
 None
 1.15A 4gc9A-4jipA:
undetectable		 4gc9A-4jipA:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUQ_A_ACTA1278_0
(NAD(P)H
DEHYDROGENASE
[QUINONE] 1)		 4jip GTN REDUCTASE
(Agrobacterium
tumefaciens) 		4 / 5 HIS A 100
GLN A 187
ILE A 104
TYR A 183
 None
None
None
HBA  A 402 (-4.3A)
 1.50A 5fuqA-4jipA:
1.0
5fuqB-4jipA:
undetectable		 5fuqA-4jipA:
21.90
5fuqB-4jipA:
21.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5V4V_A_NCAA402_0
(NADPH DEHYDROGENASE
3)		 4jip GTN REDUCTASE
(Agrobacterium
tumefaciens) 		6 / 8 THR A  25
TRP A  99
HIS A 178
ASN A 181
TYR A 183
TYR A 356
 FMN  A 401 ( 3.6A)
None
FMN  A 401 ( 3.6A)
HBA  A 402 ( 3.8A)
HBA  A 402 (-4.3A)
FMN  A 401 ( 4.2A)
 0.49A 5v4vA-4jipA:
49.3		 5v4vA-4jipA:
39.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5V4V_B_NCAB402_0
(NADPH DEHYDROGENASE
3)		 4jip GTN REDUCTASE
(Agrobacterium
tumefaciens) 		6 / 8 THR A  25
TRP A  99
HIS A 178
ASN A 181
TYR A 183
TYR A 356
 FMN  A 401 ( 3.6A)
None
FMN  A 401 ( 3.6A)
HBA  A 402 ( 3.8A)
HBA  A 402 (-4.3A)
FMN  A 401 ( 4.2A)
 0.47A 5v4vB-4jipA:
49.3		 5v4vB-4jipA:
39.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W7B_A_PA1A206_1
(ACYLOXYACYL
HYDROLASE SMALL
SUBUNIT
ACYLOXYACYL
HYDROLASE LARGE
SUBUNIT)		 4jip GTN REDUCTASE
(Agrobacterium
tumefaciens) 		4 / 4 TYR A 183
GLY A 272
ASN A 306
ARG A 230
 HBA  A 402 (-4.3A)
FMN  A 401 ( 4.0A)
FMN  A 401 (-4.4A)
FMN  A 401 (-3.0A)
 1.11A 5w7bA-4jipA:
undetectable
5w7bC-4jipA:
3.2		 5w7bA-4jipA:
10.17
5w7bC-4jipA:
9.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HCO_A_FY5A1003_0
(ATP-BINDING CASSETTE
SUB-FAMILY G MEMBER
2)		 4jip GTN REDUCTASE
(Agrobacterium
tumefaciens) 		5 / 11 THR A  53
VAL A  20
PHE A 263
ILE A 222
VAL A 175
 None
 1.44A 6hcoA-4jipA:
0.5
6hcoB-4jipA:
undetectable		 6hcoA-4jipA:
20.21
6hcoB-4jipA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MKE_A_FK5A201_0
(PEPTIDYLPROLYL
ISOMERASE)		 4jip GTN REDUCTASE
(Agrobacterium
tumefaciens) 		5 / 12 ILE A  83
TYR A  42
ILE A  51
PHE A 172
TYR A 356
 None
None
None
None
FMN  A 401 ( 4.2A)
 1.09A 6mkeA-4jipA:
undetectable
6mkeD-4jipA:
undetectable		 6mkeA-4jipA:
15.21
6mkeD-4jipA:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MKE_B_FK5B201_0
(PEPTIDYLPROLYL
ISOMERASE)		 4jip GTN REDUCTASE
(Agrobacterium
tumefaciens) 		5 / 12 ILE A  83
TYR A  42
ILE A  51
PHE A 172
TYR A 356
 None
None
None
None
FMN  A 401 ( 4.2A)
 1.07A 6mkeB-4jipA:
undetectable
6mkeC-4jipA:
undetectable		 6mkeB-4jipA:
15.21
6mkeC-4jipA:
15.21