SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4jiv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NW5_A_SAMA401_0
(MODIFICATION
METHYLASE RSRI)		 4jiv PUTATIVE
UNCHARACTERIZED
PROTEIN
(Vibrio
cholerae) 		5 / 12 ASP D  80
GLY D  61
SER D  62
VAL D  65
ALA D  59
 None
 1.18A 1nw5A-4jivD:
undetectable		 1nw5A-4jivD:
17.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R55_A_097A518_1
(ADAM 33)		 4jiv PUTATIVE
UNCHARACTERIZED
PROTEIN
(Vibrio
cholerae) 		5 / 10 ALA D  24
THR D  23
VAL D  22
HIS D  46
ALA D  57
 None
None
None
ZN  D 101 (-3.4A)
None
 0.95A 1r55A-4jivD:
undetectable		 1r55A-4jivD:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_J_BEZJ5041_0
(CES1 PROTEIN)		 4jiv PUTATIVE
UNCHARACTERIZED
PROTEIN
(Vibrio
cholerae) 		4 / 4 GLY D   2
SER D  89
ILE D   5
HIS D   9
 None
 1.13A 1yajJ-4jivD:
undetectable		 1yajJ-4jivD:
12.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NVC_A_SALA370_1
(GENTISATE
1,2-DIOXYGENASE)		 4jiv PUTATIVE
UNCHARACTERIZED
PROTEIN
(Vibrio
cholerae) 		4 / 6 HIS D  46
HIS D  14
HIS D  54
ASP D  80
 ZN  D 101 (-3.4A)
ZN  D 101 (-3.3A)
ZN  D 101 (-3.2A)
None
 1.04A 3nvcA-4jivD:
undetectable		 3nvcA-4jivD:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDN_P_EVPP2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 4jiv PUTATIVE
UNCHARACTERIZED
PROTEIN
(Vibrio
cholerae) 		4 / 6 SER D  26
ASP D  77
ARG D  74
GLY D   4
 None
 0.77A 5cdnT-4jivD:
undetectable
5cdnU-4jivD:
undetectable		 5cdnT-4jivD:
14.13
5cdnU-4jivD:
15.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_A_CUA606_0
(TYROSINASE)		 4jiv PUTATIVE
UNCHARACTERIZED
PROTEIN
(Vibrio
cholerae) 		4 / 4 HIS D  14
CYH D  81
HIS D  54
HIS D  46
 ZN  D 101 (-3.3A)
ZN  D 101 (-2.3A)
ZN  D 101 (-3.2A)
ZN  D 101 (-3.4A)
 1.44A 5zrdA-4jivD:
undetectable		 5zrdA-4jivD:
10.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BXM_A_SAMA402_0
(DIPHTHAMIDE
BIOSYNTHESIS ENZYME
DPH2)		 4jiv PUTATIVE
UNCHARACTERIZED
PROTEIN
(Vibrio
cholerae) 		5 / 12 GLY D  94
VAL D   6
ARG D  74
ILE D   5
ASP D  77
 None
 1.23A 6bxmA-4jivD:
undetectable		 6bxmA-4jivD:
15.29