SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4jiw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKP_C_478C200_2
(PROTEASE)		 4jiw PUTATIVE
UNCHARACTERIZED
PROTEIN
(Escherichia
coli) 		6 / 10 ASP D  41
GLY D  25
ALA D  37
ASP D   9
VAL D  85
ILE D  58
 None
 1.35A 3ekpD-4jiwD:
undetectable		 3ekpD-4jiwD:
24.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKT_D_017D200_1
(PROTEASE)		 4jiw PUTATIVE
UNCHARACTERIZED
PROTEIN
(Escherichia
coli) 		6 / 11 ASP D  41
GLY D  25
ALA D  37
ASP D   9
VAL D  85
ILE D  58
 None
 1.33A 3ektC-4jiwD:
undetectable		 3ektC-4jiwD:
24.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKV_A_478A200_1
(PROTEASE)		 4jiw PUTATIVE
UNCHARACTERIZED
PROTEIN
(Escherichia
coli) 		6 / 10 ASP D  41
GLY D  25
ALA D  37
ASP D   9
VAL D  85
ILE D  58
 None
 1.35A 3ekvA-4jiwD:
undetectable		 3ekvA-4jiwD:
26.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NVC_A_SALA370_1
(GENTISATE
1,2-DIOXYGENASE)		 4jiw PUTATIVE
UNCHARACTERIZED
PROTEIN
(Escherichia
coli) 		4 / 6 HIS D  46
HIS D  14
HIS D  54
ASP D  80
 ZN  D 101 (-3.1A)
ZN  D 101 (-3.2A)
ZN  D 101 (-2.9A)
None
 1.11A 3nvcA-4jiwD:
undetectable		 3nvcA-4jiwD:
14.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WSJ_A_MK1A201_1
(PROTEASE)		 4jiw PUTATIVE
UNCHARACTERIZED
PROTEIN
(Escherichia
coli) 		5 / 9 ARG D  56
LEU D  43
ALA D  37
LEU D  34
ILE D  22
 None
 1.41A 3wsjA-4jiwD:
undetectable		 3wsjA-4jiwD:
27.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_A_SAMA401_1
(METHYLTRANSFERASE
NSUN4)		 4jiw PUTATIVE
UNCHARACTERIZED
PROTEIN
(Escherichia
coli) 		3 / 3 ASP D  77
ARG D  74
ASP D  41
 None
 0.68A 4fp9A-4jiwD:
undetectable		 4fp9A-4jiwD:
12.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LL3_A_017A201_2
(PROTEASE)		 4jiw PUTATIVE
UNCHARACTERIZED
PROTEIN
(Escherichia
coli) 		6 / 10 ASP D  41
GLY D  25
ALA D  37
ASP D   9
VAL D  85
ILE D  58
 None
 1.33A 4ll3B-4jiwD:
undetectable		 4ll3B-4jiwD:
30.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LL3_A_017A202_1
(PROTEASE)		 4jiw PUTATIVE
UNCHARACTERIZED
PROTEIN
(Escherichia
coli) 		6 / 10 ASP D  41
GLY D  25
ALA D  37
ASP D   9
VAL D  85
ILE D  58
 None
 1.33A 4ll3A-4jiwD:
undetectable		 4ll3A-4jiwD:
30.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LL3_A_017A202_2
(PROTEASE)		 4jiw PUTATIVE
UNCHARACTERIZED
PROTEIN
(Escherichia
coli) 		5 / 9 ASP D  41
ALA D  37
ASP D   9
VAL D  85
ILE D  58
 None
 1.14A 4ll3B-4jiwD:
undetectable		 4ll3B-4jiwD:
30.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_A_CUA606_0
(TYROSINASE)		 4jiw PUTATIVE
UNCHARACTERIZED
PROTEIN
(Escherichia
coli) 		4 / 4 HIS D  14
CYH D  81
HIS D  54
HIS D  46
 ZN  D 101 (-3.2A)
ZN  D 101 (-2.3A)
ZN  D 101 (-2.9A)
ZN  D 101 (-3.1A)
 1.44A 5zrdA-4jiwD:
undetectable		 5zrdA-4jiwD:
11.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GIQ_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4jiw PUTATIVE
UNCHARACTERIZED
PROTEIN
(Escherichia
coli) 		3 / 3 HIS D  14
HIS D  54
HIS D  46
 ZN  D 101 (-3.2A)
ZN  D 101 (-2.9A)
ZN  D 101 (-3.1A)
 0.69A 6giqa-4jiwD:
undetectable		 6giqa-4jiwD:
12.86