SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4jj3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XP0_A_VDNA201_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 4jj3 MAMP
(Magnetococcus
marinus) 		5 / 10 LEU A 120
ALA A  99
ILE A 121
ALA A 141
LEU A 176
 None
 1.16A 1xp0A-4jj3A:
undetectable		 1xp0A-4jj3A:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V95_A_HCYA1375_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 4jj3 MAMP
(Magnetococcus
marinus) 		5 / 12 ALA A  84
PRO A  85
VAL A  87
THR A 221
LYS A  80
 None
 1.33A 2v95A-4jj3A:
undetectable		 2v95A-4jj3A:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_D_SAMD300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 4jj3 MAMP
(Magnetococcus
marinus) 		5 / 12 LEU A 116
GLU A 156
ALA A 141
GLY A 118
LEU A 139
 None
 1.41A 3ou6D-4jj3A:
undetectable		 3ou6D-4jj3A:
22.98