SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4jj9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IKV_A_EFZA2000_1
(POL POLYPROTEIN)		 4jj9 5-CARBOXYMETHYL-2-HY
DROXYMUCONATE
DELTA-ISOMERASE
(Bordetella
bronchiseptica) 		5 / 9 LEU A  16
VAL A 116
TYR A   8
GLY A  75
LEU A 107
 None
 1.48A 1ikvA-4jj9A:
undetectable		 1ikvA-4jj9A:
13.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LW0_A_NVPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)		 4jj9 5-CARBOXYMETHYL-2-HY
DROXYMUCONATE
DELTA-ISOMERASE
(Bordetella
bronchiseptica) 		5 / 10 LEU A  16
VAL A 116
TYR A   8
GLY A  75
LEU A 107
 None
 1.36A 1lw0A-4jj9A:
undetectable		 1lw0A-4jj9A:
13.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VRT_A_NVPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)		 4jj9 5-CARBOXYMETHYL-2-HY
DROXYMUCONATE
DELTA-ISOMERASE
(Bordetella
bronchiseptica) 		5 / 9 LEU A  16
VAL A 116
TYR A   8
GLY A  75
LEU A 107
 None
 1.35A 1vrtA-4jj9A:
undetectable		 1vrtA-4jj9A:
13.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JJP_A_KLNA413_1
(CYTOCHROME P450
113A1)		 4jj9 5-CARBOXYMETHYL-2-HY
DROXYMUCONATE
DELTA-ISOMERASE
(Bordetella
bronchiseptica) 		5 / 12 ALA A  26
LEU A  25
ALA A  28
THR A  98
ILE A 122
 None
 1.29A 2jjpA-4jj9A:
undetectable		 2jjpA-4jj9A:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HVT_A_NVPA557_1
(HIV-1 REVERSE
TRANSCRIPTASE
(SUBUNIT P66))		 4jj9 5-CARBOXYMETHYL-2-HY
DROXYMUCONATE
DELTA-ISOMERASE
(Bordetella
bronchiseptica) 		5 / 9 LEU A  16
VAL A 116
TYR A   8
GLY A  75
LEU A 107
 None
 1.34A 3hvtA-4jj9A:
undetectable		 3hvtA-4jj9A:
13.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MEC_A_65BA561_0
(P66 REVERSE
TRANSCRIPTASE)		 4jj9 5-CARBOXYMETHYL-2-HY
DROXYMUCONATE
DELTA-ISOMERASE
(Bordetella
bronchiseptica) 		5 / 12 LEU A 107
VAL A 116
TYR A   8
GLY A 117
LEU A  79
 None
 1.13A 3mecA-4jj9A:
undetectable		 3mecA-4jj9A:
13.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEN_B_VDYB201_2
(CDL2.2)		 4jj9 5-CARBOXYMETHYL-2-HY
DROXYMUCONATE
DELTA-ISOMERASE
(Bordetella
bronchiseptica) 		5 / 12 LEU A 110
LEU A 107
ILE A  99
ALA A  50
LEU A   4
 None
 1.23A 5ienB-4jj9A:
undetectable		 5ienB-4jj9A:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X24_A_LSNA503_1
(CYTOCHROME P450 2C9)		 4jj9 5-CARBOXYMETHYL-2-HY
DROXYMUCONATE
DELTA-ISOMERASE
(Bordetella
bronchiseptica) 		4 / 6 PHE A  41
PRO A  42
GLY A  45
THR A  46
 None
 0.83A 5x24A-4jj9A:
undetectable		 5x24A-4jj9A:
16.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YSI_A_NCAA1001_0
(UBIQUITINATING/DEUBI
QUITINATING ENZYME
SDEA)		 4jj9 5-CARBOXYMETHYL-2-HY
DROXYMUCONATE
DELTA-ISOMERASE
(Bordetella
bronchiseptica) 		4 / 6 ARG A  87
GLY A  84
SER A  88
VAL A 124
 None
 1.22A 5ysiA-4jj9A:
undetectable		 5ysiA-4jj9A:
19.08