SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4jjh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AJV_L_COCL501_1
(ANTIBODY 7A1 FAB')		 4jjh POLIOVIRUS
RECEPTOR-RELATED
PROTEIN 4
(Homo
sapiens) 		4 / 7 ALA A 139
ARG A 140
TYR A 125
TYR A  94
 None
 1.21A 2ajvH-4jjhA:
11.0
2ajvL-4jjhA:
4.6		 2ajvH-4jjhA:
19.28
2ajvL-4jjhA:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PFG_A_SAMA264_1
(N-METHYLTRANSFERASE)		 4jjh POLIOVIRUS
RECEPTOR-RELATED
PROTEIN 4
(Homo
sapiens) 		3 / 3 TYR A  94
TYR A 125
GLU A  78
 None
 0.78A 3pfgA-4jjhA:
undetectable		 3pfgA-4jjhA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FI4_B_DVAB8_0
(14-3-3 PROTEIN SIGMA
PRO-SEP-LEU-PRO-DVA)		 4jjh POLIOVIRUS
RECEPTOR-RELATED
PROTEIN 4
(Homo
sapiens) 		4 / 5 SER A 111
VAL A 112
LYS A  49
PRO A 102
 None
 1.46A 6fi4A-4jjhA:
undetectable
6fi4B-4jjhA:
undetectable		 6fi4A-4jjhA:
20.33
6fi4B-4jjhA:
60.00