SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4jjm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		 4jjm PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Citrus
sinensis) 		3 / 3 TYR A  55
GLY A  57
PHE A  74
 None
 0.64A 2m2pB-4jjmA:
undetectable		 2m2pB-4jjmA:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_O_TFPO201_1
(PROTEIN S100-A4)		 4jjm PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Citrus
sinensis) 		4 / 8 GLY A  82
CYH A 168
GLY A  71
PHE A  60
 None
 1.00A 3ko0O-4jjmA:
undetectable
3ko0Q-4jjmA:
undetectable		 3ko0O-4jjmA:
20.12
3ko0Q-4jjmA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_1_BEZ1801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 4jjm PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Citrus
sinensis) 		3 / 3 LEU A 105
PHE A  25
ILE A 104
 None
 0.66A 5dzk1-4jjmA:
undetectable
5dzkF-4jjmA:
undetectable
5dzkM-4jjmA:
undetectable		 5dzk1-4jjmA:
0.57
5dzkF-4jjmA:
20.41
5dzkM-4jjmA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FA8_A_SAMA301_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE,
PUTATIVE)		 4jjm PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Citrus
sinensis) 		5 / 12 GLY A 116
ILE A  85
ASN A 109
PHE A  36
LEU A 105
 None
 1.06A 5fa8A-4jjmA:
undetectable		 5fa8A-4jjmA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IWU_A_ACTA402_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 4jjm PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Citrus
sinensis) 		4 / 6 PHE A 119
VAL A 121
MET A  10
ILE A  20
 None
 0.87A 5iwuA-4jjmA:
undetectable		 5iwuA-4jjmA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YCN_A_8LXA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 4jjm PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Citrus
sinensis) 		4 / 6 PHE A  67
CYH A 122
SER A 106
HIS A 133
 None
 1.46A 5ycnA-4jjmA:
undetectable		 5ycnA-4jjmA:
20.14