SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4jkx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MRJ_A_ADNA300_1
(ALPHA-TRICHOSANTHIN)		 4jkx BETA-GALACTOSIDE-SPE
CIFIC LECTIN 1 A
CHAIN
(Viscum
album) 		5 / 8 GLY A 113
ILE A 160
SER A 164
GLU A 165
ARG A 168
 None
H35  A 305 ( 4.5A)
None
H35  A 305 (-3.5A)
H35  A 305 (-3.3A)
 0.47A 1mrjA-4jkxA:
32.3		 1mrjA-4jkxA:
37.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_A_VDYA1002_1
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 4jkx BETA-GALACTOSIDE-SPE
CIFIC LECTIN 1 A
CHAIN
(Viscum
album) 		4 / 4 ILE A 132
LEU A 135
VAL A 139
ALA A  82
 None
 0.92A 1mz9A-4jkxA:
undetectable		 1mz9A-4jkxA:
10.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_A_VDYA1002_3
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 4jkx BETA-GALACTOSIDE-SPE
CIFIC LECTIN 1 A
CHAIN
(Viscum
album) 		4 / 5 ILE A 132
LEU A 135
VAL A 139
ALA A  82
 None
 0.96A 1mz9C-4jkxA:
undetectable		 1mz9C-4jkxA:
10.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y0X_X_T44X500_2
(THYROID HORMONE
RECEPTOR BETA-1)		 4jkx BETA-GALACTOSIDE-SPE
CIFIC LECTIN 1 A
CHAIN
(Viscum
album) 		4 / 5 ILE A  70
SER A  29
ARG A  41
LEU A  75
 None
None
DIO  A 307 (-4.4A)
None
 0.92A 1y0xX-4jkxA:
undetectable		 1y0xX-4jkxA:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z9H_A_IMNA379_1
(MEMBRANE-ASSOCIATED
PROSTAGLANDIN E
SYNTHASE-2)		 4jkx BETA-GALACTOSIDE-SPE
CIFIC LECTIN 1 A
CHAIN
(Viscum
album) 		5 / 12 TYR A 179
VAL A   8
TYR A  17
ILE A 180
LEU A   6
 None
 1.38A 1z9hA-4jkxA:
undetectable		 1z9hA-4jkxA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z9H_B_IMNB381_1
(MEMBRANE-ASSOCIATED
PROSTAGLANDIN E
SYNTHASE-2)		 4jkx BETA-GALACTOSIDE-SPE
CIFIC LECTIN 1 A
CHAIN
(Viscum
album) 		5 / 12 TYR A 179
VAL A   8
TYR A  17
ILE A 180
LEU A   6
 None
 1.38A 1z9hB-4jkxA:
undetectable		 1z9hB-4jkxA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LD6_A_KKKA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 4jkx BETA-GALACTOSIDE-SPE
CIFIC LECTIN 1 A
CHAIN
(Viscum
album) 		5 / 12 TYR A  17
PHE A 186
GLY A 183
ILE A 158
ILE A 160
 None
None
None
None
H35  A 305 ( 4.5A)
 1.41A 3ld6A-4jkxA:
undetectable		 3ld6A-4jkxA:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_C_ACTC610_0
(GBAA_1210 PROTEIN)		 4jkx BETA-GALACTOSIDE-SPE
CIFIC LECTIN 1 A
CHAIN
(Viscum
album) 		3 / 3 ASN A 170
ALA A 241
ARG A  25
 None
 0.90A 3tj7C-4jkxA:
undetectable
3tj7D-4jkxA:
undetectable		 3tj7C-4jkxA:
19.76
3tj7D-4jkxA:
19.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U6T_A_KANA4699_1
(RIBOSOME
INACTIVATING PROTEIN)		 4jkx BETA-GALACTOSIDE-SPE
CIFIC LECTIN 1 A
CHAIN
(Viscum
album) 		5 / 10 TYR A  76
ASN A 112
ILE A 160
GLU A 165
ARG A 168
 H35  A 305 (-4.2A)
NAG  A 302 (-1.9A)
H35  A 305 ( 4.5A)
H35  A 305 (-3.5A)
H35  A 305 (-3.3A)
 1.17A 3u6tA-4jkxA:
32.4		 3u6tA-4jkxA:
33.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_I_ZPCI1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 4jkx BETA-GALACTOSIDE-SPE
CIFIC LECTIN 1 A
CHAIN
(Viscum
album) 		4 / 7 PHE A 214
VAL A 206
ILE A  37
ASN A  35
 None
 1.14A 4a97H-4jkxA:
undetectable		 4a97H-4jkxA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_B_DXCB1473_0
(MJ0495-LIKE PROTEIN)		 4jkx BETA-GALACTOSIDE-SPE
CIFIC LECTIN 1 A
CHAIN
(Viscum
album) 		5 / 11 ILE A 136
ILE A 132
GLY A 131
SER A  19
GLY A  14
 None
 0.94A 4ac9B-4jkxA:
undetectable
4ac9C-4jkxA:
undetectable		 4ac9B-4jkxA:
19.06
4ac9C-4jkxA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AFT_D_QMRD301_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 4jkx BETA-GALACTOSIDE-SPE
CIFIC LECTIN 1 A
CHAIN
(Viscum
album) 		4 / 8 TYR A 191
VAL A 236
VAL A 206
ILE A 218
 None
 1.12A 4aftD-4jkxA:
undetectable
4aftE-4jkxA:
undetectable		 4aftD-4jkxA:
22.78
4aftE-4jkxA:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CEV_A_GAIA407_0
(PROTEIN (ARGINASE))		 4jkx BETA-GALACTOSIDE-SPE
CIFIC LECTIN 1 A
CHAIN
(Viscum
album) 		4 / 6 ARG A 175
LEU A 195
MET A 192
ASP A 189
 None
 1.04A 4cevA-4jkxA:
undetectable
4cevB-4jkxA:
undetectable		 4cevA-4jkxA:
27.18
4cevB-4jkxA:
27.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CEV_C_GAIC409_0
(PROTEIN (ARGINASE))		 4jkx BETA-GALACTOSIDE-SPE
CIFIC LECTIN 1 A
CHAIN
(Viscum
album) 		4 / 6 MET A 192
ASP A 189
ARG A 175
LEU A 195
 None
 1.03A 4cevA-4jkxA:
undetectable
4cevC-4jkxA:
undetectable		 4cevA-4jkxA:
27.18
4cevC-4jkxA:
27.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CEV_D_GAID410_0
(PROTEIN (ARGINASE))		 4jkx BETA-GALACTOSIDE-SPE
CIFIC LECTIN 1 A
CHAIN
(Viscum
album) 		4 / 6 ARG A 175
LEU A 195
MET A 192
ASP A 189
 None
 1.06A 4cevD-4jkxA:
undetectable
4cevE-4jkxA:
undetectable		 4cevD-4jkxA:
27.18
4cevE-4jkxA:
27.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CEV_F_GAIF411_0
(PROTEIN (ARGINASE))		 4jkx BETA-GALACTOSIDE-SPE
CIFIC LECTIN 1 A
CHAIN
(Viscum
album) 		4 / 6 ARG A 175
LEU A 195
MET A 192
ASP A 189
 None
 1.05A 4cevE-4jkxA:
undetectable
4cevF-4jkxA:
undetectable		 4cevE-4jkxA:
27.18
4cevF-4jkxA:
27.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J14_A_X2NA602_1
(CHOLESTEROL
24-HYDROXYLASE)		 4jkx BETA-GALACTOSIDE-SPE
CIFIC LECTIN 1 A
CHAIN
(Viscum
album) 		5 / 10 ALA A 167
LEU A  24
PHE A  20
THR A  67
ALA A  69
 None
 1.09A 4j14A-4jkxA:
undetectable		 4j14A-4jkxA:
21.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YP2_B_NCAB302_0
(RIBOSOME-INACTIVATIN
G PROTEIN MOMORDIN I)		 4jkx BETA-GALACTOSIDE-SPE
CIFIC LECTIN 1 A
CHAIN
(Viscum
album) 		5 / 9 TYR A  76
GLY A 113
ILE A 160
GLU A 165
ARG A 168
 H35  A 305 (-4.2A)
None
H35  A 305 ( 4.5A)
H35  A 305 (-3.5A)
H35  A 305 (-3.3A)
 0.86A 4yp2B-4jkxA:
32.4		 4yp2B-4jkxA:
33.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CF9_B_NCAB302_0
(RIBOSOME-INACTIVATIN
G PROTEIN MOMORDIN I)		 4jkx BETA-GALACTOSIDE-SPE
CIFIC LECTIN 1 A
CHAIN
(Viscum
album) 		5 / 9 TYR A  76
GLY A 113
ILE A 160
GLU A 165
ARG A 168
 H35  A 305 (-4.2A)
None
H35  A 305 ( 4.5A)
H35  A 305 (-3.5A)
H35  A 305 (-3.3A)
 0.83A 5cf9B-4jkxA:
32.5		 5cf9B-4jkxA:
33.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NY7_A_NCAA303_0
(AMIDASE)		 4jkx BETA-GALACTOSIDE-SPE
CIFIC LECTIN 1 A
CHAIN
(Viscum
album) 		4 / 6 ARG A   5
THR A  67
GLU A  57
SER A  65
 None
None
None
EDO  A 306 (-4.3A)
 1.10A 5ny7A-4jkxA:
undetectable		 5ny7A-4jkxA:
20.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Z3J_A_NCAA302_0
(ABRIN A-CHAIN)		 4jkx BETA-GALACTOSIDE-SPE
CIFIC LECTIN 1 A
CHAIN
(Viscum
album) 		5 / 6 TYR A  76
VAL A  77
ILE A 160
GLU A 165
ARG A 168
 H35  A 305 (-4.2A)
None
H35  A 305 ( 4.5A)
H35  A 305 (-3.5A)
H35  A 305 (-3.3A)
 0.54A 5z3jA-4jkxA:
35.4		 5z3jA-4jkxA:
40.36