SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4jl0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_A_RBFA200_1
(DODECIN)		 4jl0 REGULATORY PROTEIN
PCRH
(Pseudomonas
aeruginosa) 		4 / 8 ARG A 105
GLN A  48
HIS A 109
GLN A  81
 None
 1.30A 2vxaA-4jl0A:
undetectable
2vxaC-4jl0A:
undetectable
2vxaE-4jl0A:
undetectable		 2vxaA-4jl0A:
17.27
2vxaC-4jl0A:
17.27
2vxaE-4jl0A:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_B_RBFB200_1
(DODECIN)		 4jl0 REGULATORY PROTEIN
PCRH
(Pseudomonas
aeruginosa) 		4 / 8 GLN A  48
ARG A 105
HIS A 109
GLN A  81
 None
 1.31A 2vxaA-4jl0A:
undetectable
2vxaB-4jl0A:
undetectable
2vxaK-4jl0A:
undetectable		 2vxaA-4jl0A:
17.27
2vxaB-4jl0A:
17.27
2vxaK-4jl0A:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_C_RBFC200_1
(DODECIN)		 4jl0 REGULATORY PROTEIN
PCRH
(Pseudomonas
aeruginosa) 		4 / 8 GLN A  48
ARG A 105
HIS A 109
GLN A  81
 None
 1.29A 2vxaB-4jl0A:
undetectable
2vxaC-4jl0A:
undetectable
2vxaG-4jl0A:
undetectable		 2vxaB-4jl0A:
17.27
2vxaC-4jl0A:
17.27
2vxaG-4jl0A:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_D_RBFD200_1
(DODECIN)		 4jl0 REGULATORY PROTEIN
PCRH
(Pseudomonas
aeruginosa) 		4 / 8 ARG A 105
GLN A  48
HIS A 109
GLN A  81
 None
 1.29A 2vxaD-4jl0A:
undetectable
2vxaF-4jl0A:
undetectable
2vxaI-4jl0A:
undetectable		 2vxaD-4jl0A:
17.27
2vxaF-4jl0A:
17.27
2vxaI-4jl0A:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_E_RBFE200_1
(DODECIN)		 4jl0 REGULATORY PROTEIN
PCRH
(Pseudomonas
aeruginosa) 		4 / 8 GLN A  48
ARG A 105
HIS A 109
GLN A  81
 None
 1.29A 2vxaD-4jl0A:
undetectable
2vxaE-4jl0A:
undetectable
2vxaL-4jl0A:
undetectable		 2vxaD-4jl0A:
17.27
2vxaE-4jl0A:
17.27
2vxaL-4jl0A:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_G_RBFG200_1
(DODECIN)		 4jl0 REGULATORY PROTEIN
PCRH
(Pseudomonas
aeruginosa) 		4 / 8 HIS A 109
GLN A  81
ARG A 105
GLN A  48
 None
 1.27A 2vxaF-4jl0A:
undetectable
2vxaG-4jl0A:
undetectable
2vxaI-4jl0A:
undetectable		 2vxaF-4jl0A:
17.27
2vxaG-4jl0A:
17.27
2vxaI-4jl0A:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_H_RBFH200_1
(DODECIN)		 4jl0 REGULATORY PROTEIN
PCRH
(Pseudomonas
aeruginosa) 		4 / 8 HIS A 109
GLN A  81
GLN A  48
ARG A 105
 None
 1.28A 2vxaB-4jl0A:
undetectable
2vxaG-4jl0A:
undetectable
2vxaH-4jl0A:
undetectable		 2vxaB-4jl0A:
17.27
2vxaG-4jl0A:
17.27
2vxaH-4jl0A:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_I_RBFI200_1
(DODECIN)		 4jl0 REGULATORY PROTEIN
PCRH
(Pseudomonas
aeruginosa) 		4 / 8 GLN A  48
ARG A 105
HIS A 109
GLN A  81
 None
 1.29A 2vxaH-4jl0A:
undetectable
2vxaI-4jl0A:
undetectable
2vxaJ-4jl0A:
undetectable		 2vxaH-4jl0A:
17.27
2vxaI-4jl0A:
17.27
2vxaJ-4jl0A:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_J_RBFJ200_1
(DODECIN)		 4jl0 REGULATORY PROTEIN
PCRH
(Pseudomonas
aeruginosa) 		4 / 8 HIS A 109
GLN A  81
ARG A 105
GLN A  48
 None
 1.28A 2vxaD-4jl0A:
undetectable
2vxaJ-4jl0A:
undetectable
2vxaL-4jl0A:
undetectable		 2vxaD-4jl0A:
17.27
2vxaJ-4jl0A:
17.27
2vxaL-4jl0A:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_K_RBFK200_1
(DODECIN)		 4jl0 REGULATORY PROTEIN
PCRH
(Pseudomonas
aeruginosa) 		4 / 8 HIS A 109
GLN A  81
GLN A  48
ARG A 105
 None
 1.28A 2vxaH-4jl0A:
undetectable
2vxaJ-4jl0A:
undetectable
2vxaK-4jl0A:
undetectable		 2vxaH-4jl0A:
17.27
2vxaJ-4jl0A:
17.27
2vxaK-4jl0A:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_L_RBFL200_1
(DODECIN)		 4jl0 REGULATORY PROTEIN
PCRH
(Pseudomonas
aeruginosa) 		4 / 8 HIS A 109
GLN A  81
GLN A  48
ARG A 105
 None
 1.29A 2vxaA-4jl0A:
undetectable
2vxaK-4jl0A:
undetectable
2vxaL-4jl0A:
undetectable		 2vxaA-4jl0A:
17.27
2vxaK-4jl0A:
17.27
2vxaL-4jl0A:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZV_B_ECNB411_1
(FLAVOHEMOGLOBIN)		 4jl0 REGULATORY PROTEIN
PCRH
(Pseudomonas
aeruginosa) 		5 / 9 PHE A 108
GLN A  81
ALA A  78
LEU A 143
ALA A 130
 None
 1.06A 3ozvB-4jl0A:
undetectable		 3ozvB-4jl0A:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UL4_A_SAMA803_0
(OXSB PROTEIN)		 4jl0 REGULATORY PROTEIN
PCRH
(Pseudomonas
aeruginosa) 		5 / 12 PHE A 106
ARG A  71
GLY A  75
GLY A  77
LEU A  98
 None
 1.02A 5ul4A-4jl0A:
undetectable		 5ul4A-4jl0A:
11.83