SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4jlz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_F_9CRF1600_1
(RETINOIC ACID
RECEPTOR, BETA)		 4jlz UNCHARACTERIZED
PROTEIN
(Sus
scrofa) 		5 / 12 ALA A 248
LEU A 246
ILE A 245
LEU A 214
LEU A 301
 None
 0.88A 1xdkF-4jlzA:
undetectable		 1xdkF-4jlzA:
23.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD4_B_CHDB928_0
(FERROCHELATASE)		 4jlz UNCHARACTERIZED
PROTEIN
(Sus
scrofa) 		5 / 12 LEU A 354
PHE A 356
LEU A 336
GLN A 312
VAL A 209
 None
 1.24A 2qd4B-4jlzA:
undetectable		 2qd4B-4jlzA:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEI_A_CXXA802_1
(TRANSPORTER)		 4jlz UNCHARACTERIZED
PROTEIN
(Sus
scrofa) 		4 / 6 SER A 176
PHE A 255
ILE A 259
PHE A 205
 None
 1.26A 2qeiA-4jlzA:
undetectable		 2qeiA-4jlzA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVM_A_PFLA511_1
(PROTON-GATED ION
CHANNEL)		 4jlz UNCHARACTERIZED
PROTEIN
(Sus
scrofa) 		5 / 8 ILE A 293
ALA A 156
ILE A 153
ALA A 197
GLU A 200
 None
 1.41A 5mvmA-4jlzA:
2.0
5mvmB-4jlzA:
2.2		 5mvmA-4jlzA:
11.39
5mvmB-4jlzA:
11.39