SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4jm0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_F_FUAF704_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 4jm0 PROTEIN UL141
(Human
betaherpesvirus
5) 		5 / 11 THR A  50
PHE A 157
LEU A 145
VAL A  77
VAL A  69
 None
 1.40A 1q23F-4jm0A:
undetectable		 1q23F-4jm0A:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_I_FUAI707_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 4jm0 PROTEIN UL141
(Human
betaherpesvirus
5) 		5 / 11 THR A  50
PHE A 157
LEU A 145
VAL A  77
VAL A  69
 None
 1.36A 1q23I-4jm0A:
undetectable		 1q23I-4jm0A:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_K_FUAK712_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 4jm0 PROTEIN UL141
(Human
betaherpesvirus
5) 		5 / 10 THR A  50
LEU A 145
VAL A  77
PHE A 127
VAL A  69
 None
 1.43A 1q23K-4jm0A:
undetectable		 1q23K-4jm0A:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_L_FUAL710_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 4jm0 PROTEIN UL141
(Human
betaherpesvirus
5) 		5 / 11 THR A  50
PHE A 157
LEU A 145
VAL A  77
VAL A  69
 None
 1.38A 1q23L-4jm0A:
undetectable		 1q23L-4jm0A:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_H_CLMH221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 4jm0 PROTEIN UL141
(Human
betaherpesvirus
5) 		5 / 12 THR A  50
LEU A 145
VAL A  77
PHE A 127
VAL A  69
 None
 1.47A 3u9fH-4jm0A:
undetectable
3u9fI-4jm0A:
undetectable		 3u9fH-4jm0A:
21.35
3u9fI-4jm0A:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_J_CLMJ221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 4jm0 PROTEIN UL141
(Human
betaherpesvirus
5) 		5 / 12 THR A  50
LEU A 145
VAL A  77
PHE A 127
VAL A  69
 None
 1.42A 3u9fJ-4jm0A:
undetectable
3u9fK-4jm0A:
undetectable		 3u9fJ-4jm0A:
21.35
3u9fK-4jm0A:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_K_CLMK221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 4jm0 PROTEIN UL141
(Human
betaherpesvirus
5) 		5 / 10 THR A  50
LEU A 145
VAL A  77
PHE A 127
VAL A  69
 None
 1.47A 3u9fK-4jm0A:
undetectable		 3u9fK-4jm0A:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_K_CLMK221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 4jm0 PROTEIN UL141
(Human
betaherpesvirus
5) 		5 / 10 THR A  50
PHE A 157
LEU A 145
VAL A  77
VAL A  69
 None
 1.36A 3u9fK-4jm0A:
undetectable		 3u9fK-4jm0A:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_P_CLMP221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 4jm0 PROTEIN UL141
(Human
betaherpesvirus
5) 		5 / 9 THR A  50
LEU A 145
VAL A  77
PHE A 127
VAL A  69
 None
 1.48A 3u9fP-4jm0A:
undetectable		 3u9fP-4jm0A:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_B_AERB601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 4jm0 PROTEIN UL141
(Human
betaherpesvirus
5) 		5 / 12 ILE A  65
LEU A 129
GLY A 139
ALA A 138
VAL A  63
 None
 0.90A 4nkvB-4jm0A:
undetectable		 4nkvB-4jm0A:
19.08