SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4jmd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QD4_B_CHDB928_0 (FERROCHELATASE)	4jmd	PUTATIVE UNCHARACTERIZED PROTEIN MPPR (Streptomyces hygroscopicus)	5 / 12	LEU A 122 LEU A 215 GLN A 163 LEU A 285 VAL A 240	None	1.34A	2qd4B-4jmdA: undetectable	2qd4B-4jmdA: 20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3RUK_B_AERB601_1 (STEROID 17-ALPHA-HYDROXYLASE /17,20 LYASE)	4jmd	PUTATIVE UNCHARACTERIZED PROTEIN MPPR (Streptomyces hygroscopicus)	5 / 12	ALA A 92 ILE A 248 ASP A 66 GLY A 276 VAL A 62	None	0.97A	3rukB-4jmdA: undetectable	3rukB-4jmdA: 18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4R1Z_A_AERA601_1 (CYP17A1 PROTEIN)	4jmd	PUTATIVE UNCHARACTERIZED PROTEIN MPPR (Streptomyces hygroscopicus)	5 / 9	ALA A 92 ILE A 248 ASP A 66 GLY A 276 VAL A 62	None	1.14A	4r1zA-4jmdA: undetectable	4r1zA-4jmdA: 21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XP9_C_1WEC706_1 (TRANSPORTER)	4jmd	PUTATIVE UNCHARACTERIZED PROTEIN MPPR (Streptomyces hygroscopicus)	4 / 4	PHE A 182 ASP A 183 GLY A 180 SER A 164	None	1.38A	4xp9C-4jmdA: undetectable	4xp9C-4jmdA: 20.62

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2QD4_B_CHDB928_0","FERROCHELATASE","4jmd","PUTATIVE UNCHARACTERIZED PROTEIN MPPR","Streptomyces hygroscopicus",5,"LEU A 122;LEU A 215;GLN A 163;LEU A 285;VAL A 240","None","1.34A","2qd4B-4jmdA:undetectable","2qd4B-4jmdA:20.85"],["3RUK_B_AERB601_1","STEROID 17-ALPHA-HYDROXYLASE\/17,20 LYASE","4jmd","PUTATIVE UNCHARACTERIZED PROTEIN MPPR","Streptomyces hygroscopicus",5,"ALA A  92;ILE A 248;ASP A  66;GLY A 276;VAL A  62","None","0.97A","3rukB-4jmdA:undetectable","3rukB-4jmdA:18.96"],["4R1Z_A_AERA601_1","CYP17A1 PROTEIN","4jmd","PUTATIVE UNCHARACTERIZED PROTEIN MPPR","Streptomyces hygroscopicus",5,"ALA A  92;ILE A 248;ASP A  66;GLY A 276;VAL A  62","None","1.14A","4r1zA-4jmdA:undetectable","4r1zA-4jmdA:21.12"],["4XP9_C_1WEC706_1","TRANSPORTER","4jmd","PUTATIVE UNCHARACTERIZED PROTEIN MPPR","Streptomyces hygroscopicus",4,"PHE A 182;ASP A 183;GLY A 180;SER A 164","None","1.38A","4xp9C-4jmdA:undetectable","4xp9C-4jmdA:20.62"]]