SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4jmf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7C_A_HLTA4007_1
(SERUM ALBUMIN)		 4jmf EXOENZYME T
PROBABLE CHAPERONE
(Pseudomonas
aeruginosa) 		4 / 8 LEU B 105
HIS B 102
LEU A  53
LEU A  54
 None
 0.67A 1e7cA-4jmfB:
undetectable		 1e7cA-4jmfB:
14.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FK6_A_LNLA1201_1
(NON-SPECIFIC LIPID
TRANSFER PROTEIN)		 4jmf EXOENZYME T
PROBABLE CHAPERONE
(Pseudomonas
aeruginosa) 		5 / 12 LEU B  30
ALA A  59
LEU B  12
ALA B   8
ILE B 101
 None
 0.88A 1fk6A-4jmfB:
undetectable		 1fk6A-4jmfB:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HA2_A_SWFA3001_1
(SERUM ALBUMIN)		 4jmf EXOENZYME T
PROBABLE CHAPERONE
(Pseudomonas
aeruginosa) 		5 / 11 ALA A  59
LEU B  16
LEU B  30
LEU B  39
ILE B   9
 None
 1.01A 1ha2A-4jmfA:
undetectable		 1ha2A-4jmfA:
6.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD4_A_CHDA801_0
(FERROCHELATASE)		 4jmf PROBABLE CHAPERONE
(Pseudomonas
aeruginosa) 		5 / 12 LEU B  12
LEU B  39
SER B  29
LEU B  36
VAL B 109
 None
 1.17A 2qd4A-4jmfB:
undetectable		 2qd4A-4jmfB:
16.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RUK_B_AERB601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 4jmf EXOENZYME T
PROBABLE CHAPERONE
(Pseudomonas
aeruginosa) 		5 / 12 PHE B  50
ILE A  68
ILE A  69
LEU A  72
VAL B  27
 None
 0.93A 3rukB-4jmfB:
undetectable		 3rukB-4jmfB:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TTR_A_LQZA90_1
(LACTOTRANSFERRIN)		 4jmf PROBABLE CHAPERONE
(Pseudomonas
aeruginosa) 		3 / 3 PRO B  19
THR B  20
LEU B  14
 None
 0.80A 3ttrA-4jmfB:
undetectable		 3ttrA-4jmfB:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HQB_A_PQNA2001_0
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 4jmf PROBABLE CHAPERONE
(Pseudomonas
aeruginosa) 		5 / 10 TRP B  88
SER B  82
GLY B  83
ARG B  85
LEU B  93
 None
 1.42A 6hqbA-4jmfB:
undetectable
6hqbJ-4jmfB:
undetectable		 6hqbA-4jmfB:
18.80
6hqbJ-4jmfB:
18.45