SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4jmj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CMA_B_SAMB105_0
(PROTEIN (MET
REPRESSOR))		 4jmj RNA/RNP
COMPLEX-1-INTERACTIN
G PHOSPHATASE
(Homo
sapiens) 		5 / 11 LEU A  85
HIS A 105
ALA A 106
PHE A 110
GLY A 109
 None
 1.29A 1cmaA-4jmjA:
undetectable
1cmaB-4jmjA:
undetectable		 1cmaA-4jmjA:
22.09
1cmaB-4jmjA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJ2_A_SAMA2201_1
(PROTEIN (METHIONINE
REPRESSOR))		 4jmj RNA/RNP
COMPLEX-1-INTERACTIN
G PHOSPHATASE
(Homo
sapiens) 		4 / 4 HIS A 105
ALA A 106
PHE A 110
GLY A 109
 None
 1.25A 1mj2B-4jmjA:
undetectable		 1mj2B-4jmjA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJ2_C_SAMC1200_1
(PROTEIN (METHIONINE
REPRESSOR))		 4jmj RNA/RNP
COMPLEX-1-INTERACTIN
G PHOSPHATASE
(Homo
sapiens) 		4 / 4 HIS A 105
ALA A 106
PHE A 110
GLY A 109
 None
 1.23A 1mj2D-4jmjA:
undetectable		 1mj2D-4jmjA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJO_A_SAMA199_1
(METHIONINE REPRESSOR)		 4jmj RNA/RNP
COMPLEX-1-INTERACTIN
G PHOSPHATASE
(Homo
sapiens) 		4 / 4 HIS A 105
ALA A 106
PHE A 110
GLY A 109
 None
 1.27A 1mjoB-4jmjA:
undetectable		 1mjoB-4jmjA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJO_B_SAMB200_0
(METHIONINE REPRESSOR)		 4jmj RNA/RNP
COMPLEX-1-INTERACTIN
G PHOSPHATASE
(Homo
sapiens) 		4 / 4 HIS A 105
ALA A 106
PHE A 110
GLY A 109
 None
 1.34A 1mjoA-4jmjA:
undetectable		 1mjoA-4jmjA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJO_D_SAMD200_1
(METHIONINE REPRESSOR)		 4jmj RNA/RNP
COMPLEX-1-INTERACTIN
G PHOSPHATASE
(Homo
sapiens) 		4 / 4 HIS A 105
ALA A 106
PHE A 110
GLY A 109
 None
 1.24A 1mjoD-4jmjA:
undetectable		 1mjoD-4jmjA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IDW_B_017B401_1
(PROTEASE)		 4jmj RNA/RNP
COMPLEX-1-INTERACTIN
G PHOSPHATASE
(Homo
sapiens) 		5 / 11 LEU A  85
ILE A 136
ILE A 100
ALA A 106
ILE A  64
 None
 0.96A 2idwA-4jmjA:
undetectable		 2idwA-4jmjA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNK_A_ROCA401_3
(PROTEASE)		 4jmj RNA/RNP
COMPLEX-1-INTERACTIN
G PHOSPHATASE
(Homo
sapiens) 		5 / 12 LEU A 140
GLY A 133
ILE A  64
GLY A 122
ILE A  24
 None
 0.95A 2nnkB-4jmjA:
undetectable		 2nnkB-4jmjA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UXD_B_ZITB501_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E MPHH)		 4jmj RNA/RNP
COMPLEX-1-INTERACTIN
G PHOSPHATASE
(Homo
sapiens) 		5 / 12 LEU A  66
LEU A  78
VAL A  82
TYR A  73
PHE A  44
 None
 0.94A 5uxdB-4jmjA:
undetectable		 5uxdB-4jmjA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZSF_B_6T0B913_0
(TOLL-LIKE RECEPTOR 7)		 4jmj RNA/RNP
COMPLEX-1-INTERACTIN
G PHOSPHATASE
(Homo
sapiens) 		5 / 9 VAL A 107
PHE A 103
THR A  89
LEU A  66
THR A 132
 None
 1.50A 5zsfA-4jmjA:
undetectable
5zsfB-4jmjA:
0.0		 5zsfA-4jmjA:
22.50
5zsfB-4jmjA:
22.50