SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4jmn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AKD_A_CAMA420_0
(CYTOCHROME P450CAM)		 4jmn PROBABLE
L,D-TRANSPEPTIDASE
LDTA
(Mycobacterium
tuberculosis) 		5 / 11 LEU A 125
VAL A 138
GLY A 127
VAL A 198
VAL A 207
 None
 1.28A 1akdA-4jmnA:
undetectable		 1akdA-4jmnA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FPQ_A_SAMA1699_0
(ISOLIQUIRITIGENIN
2'-O-METHYLTRANSFERA
SE)		 4jmn PROBABLE
L,D-TRANSPEPTIDASE
LDTA
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  51
ASP A 245
LEU A 125
VAL A 241
ALA A  48
 None
 1.44A 1fpqA-4jmnA:
undetectable		 1fpqA-4jmnA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JR1_B_MOAB1333_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE 2)		 4jmn PROBABLE
L,D-TRANSPEPTIDASE
LDTA
(Mycobacterium
tuberculosis) 		4 / 8 ASN A 228
GLY A 153
THR A 159
GLY A 204
 None
 0.87A 1jr1B-4jmnA:
undetectable		 1jr1B-4jmnA:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGP_A_PCFA1213_1
(WNT INHIBITORY
FACTOR 1)		 4jmn PROBABLE
L,D-TRANSPEPTIDASE
LDTA
(Mycobacterium
tuberculosis) 		5 / 9 ILE A 131
ILE A 161
ILE A 227
PHE A 164
VAL A  89
 None
 1.50A 2ygpA-4jmnA:
undetectable		 2ygpA-4jmnA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CZH_A_D2VA602_1
(CYTOCHROME P450 2R1)		 4jmn PROBABLE
L,D-TRANSPEPTIDASE
LDTA
(Mycobacterium
tuberculosis) 		5 / 12 VAL A 200
ALA A 166
VAL A 173
THR A 159
VAL A 249
 None
 1.05A 3czhA-4jmnA:
undetectable		 3czhA-4jmnA:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MSS_D_STID1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 4jmn PROBABLE
L,D-TRANSPEPTIDASE
LDTA
(Mycobacterium
tuberculosis) 		4 / 6 VAL A 198
VAL A 250
VAL A 138
ILE A 227
 None
 0.98A 3mssD-4jmnA:
undetectable		 3mssD-4jmnA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FO4_B_MOAB502_1
(INOSINE
5'-MONOPHOSPHATE
DEHYDROGENASE)		 4jmn PROBABLE
L,D-TRANSPEPTIDASE
LDTA
(Mycobacterium
tuberculosis) 		4 / 8 ASN A 228
GLY A 153
THR A 159
GLY A 204
 None
 0.80A 4fo4B-4jmnA:
undetectable		 4fo4B-4jmnA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GQB_A_GCSA605_1
(CHITINASE)		 4jmn PROBABLE
L,D-TRANSPEPTIDASE
LDTA
(Mycobacterium
tuberculosis) 		3 / 3 TRP A  88
ILE A  74
SER A  73
 None
 1.00A 5gqbA-4jmnA:
2.7		 5gqbA-4jmnA:
17.12