SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4jmq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRC_A_CHDA702_0
(FERROCHELATASE)		 4jmq BACTERIOPHAGE T5
DISTAL TAIL PROTEIN
(Escherichia
virus
T5) 		4 / 7 ARG A 201
PRO A   4
VAL A  81
MET A   1
 None
 1.15A 2hrcA-4jmqA:
undetectable		 2hrcA-4jmqA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD4_A_CHDA802_0
(FERROCHELATASE)		 4jmq BACTERIOPHAGE T5
DISTAL TAIL PROTEIN
(Escherichia
virus
T5) 		4 / 6 ARG A 201
PRO A   4
VAL A  81
MET A   1
 None
 1.14A 2qd4A-4jmqA:
undetectable		 2qd4A-4jmqA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FL9_H_TOPH200_1
(DIHYDROFOLATE
REDUCTASE (DHFR))		 4jmq BACTERIOPHAGE T5
DISTAL TAIL PROTEIN
(Escherichia
virus
T5) 		5 / 9 GLU A 164
LEU A 129
ILE A 150
LEU A 152
THR A 161
 None
 1.37A 3fl9H-4jmqA:
undetectable		 3fl9H-4jmqA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_A_PZIA800_0
(GLUTAMATE RECEPTOR 2)		 4jmq BACTERIOPHAGE T5
DISTAL TAIL PROTEIN
(Escherichia
virus
T5) 		4 / 7 TYR A  54
ASN A   9
LEU A  15
ASP A   5
 None
 1.22A 3lslA-4jmqA:
undetectable
3lslD-4jmqA:
undetectable		 3lslA-4jmqA:
19.85
3lslD-4jmqA:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_G_PZIG800_0
(GLUTAMATE RECEPTOR 2)		 4jmq BACTERIOPHAGE T5
DISTAL TAIL PROTEIN
(Escherichia
virus
T5) 		4 / 6 TYR A  54
ASN A   9
LEU A  15
ASP A   5
 None
 1.18A 3lslG-4jmqA:
undetectable		 3lslG-4jmqA:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P68_A_MTXA201_1
(DIHYDROFOLATE
REDUCTASE)		 4jmq BACTERIOPHAGE T5
DISTAL TAIL PROTEIN
(Escherichia
virus
T5) 		5 / 11 ILE A 138
PHE A 127
LYS A 128
ILE A 100
ILE A 150
 None
 1.47A 4p68A-4jmqA:
undetectable		 4p68A-4jmqA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMK_A_EF2A151_1
(CEREBLON ISOFORM 4)		 4jmq BACTERIOPHAGE T5
DISTAL TAIL PROTEIN
(Escherichia
virus
T5) 		4 / 8 ASN A   9
PRO A  10
PHE A  64
TYR A  54
 None
 1.43A 5amkA-4jmqA:
undetectable		 5amkA-4jmqA:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KLA_A_ACTA1505_0
(MATERNAL PROTEIN
PUMILIO)		 4jmq BACTERIOPHAGE T5
DISTAL TAIL PROTEIN
(Escherichia
virus
T5) 		3 / 3 HIS A 132
LYS A 134
PHE A 157
 None
 0.91A 5klaA-4jmqA:
undetectable		 5klaA-4jmqA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LRB_A_ACRA1003_1
(ALPHA-1,4 GLUCAN
PHOSPHORYLASE)		 4jmq BACTERIOPHAGE T5
DISTAL TAIL PROTEIN
(Escherichia
virus
T5) 		4 / 6 GLU A  87
THR A   8
TYR A   7
PHE A  89
 None
 1.35A 5lrbA-4jmqA:
undetectable		 5lrbA-4jmqA:
13.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NOO_A_D16A402_1
(THYMIDYLATE SYNTHASE)		 4jmq BACTERIOPHAGE T5
DISTAL TAIL PROTEIN
(Escherichia
virus
T5) 		4 / 7 TYR A  62
ILE A 196
LEU A  15
GLY A  14
 None
 0.88A 5nooA-4jmqA:
undetectable		 5nooA-4jmqA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NOO_B_D16B402_1
(THYMIDYLATE SYNTHASE)		 4jmq BACTERIOPHAGE T5
DISTAL TAIL PROTEIN
(Escherichia
virus
T5) 		4 / 7 TYR A  62
ILE A 196
LEU A  15
GLY A  14
 None
 0.83A 5nooB-4jmqA:
undetectable		 5nooB-4jmqA:
20.54