SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4jn7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4Y_A_TPVA501_1
(PROTEIN (HIV-1
PROTEASE))		 4jn7 ENOLASE
(Agrobacterium
tumefaciens) 		5 / 10 LEU A  23
ILE A 266
GLY A 270
ILE A  86
VAL A  21
 None
 1.08A 1d4yA-4jn7A:
undetectable		 1d4yA-4jn7A:
13.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GEB_A_CAMA418_0
(CYTOCHROME P450-CAM)		 4jn7 ENOLASE
(Agrobacterium
tumefaciens) 		5 / 9 VAL A 289
ILE A 278
VAL A 269
ASP A 265
ILE A 266
 None
 1.36A 1gebA-4jn7A:
undetectable		 1gebA-4jn7A:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_A_VDYA1002_5
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 4jn7 ENOLASE
(Agrobacterium
tumefaciens) 		4 / 4 LEU A 261
VAL A 237
CYH A 236
ALA A 208
 None
 1.29A 1mz9E-4jn7A:
undetectable		 1mz9E-4jn7A:
7.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_A_CTXA11_1
(CES1 PROTEIN)		 4jn7 ENOLASE
(Agrobacterium
tumefaciens) 		4 / 8 PRO A 218
LEU A 230
GLY A 228
LEU A 238
 None
 0.91A 1ya4A-4jn7A:
2.6		 1ya4A-4jn7A:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_A_MK1A901_1
(POL POLYPROTEIN)		 4jn7 ENOLASE
(Agrobacterium
tumefaciens) 		5 / 12 GLY A  33
ILE A  86
GLY A 270
GLY A 271
ILE A 272
 None
 0.78A 2avvA-4jn7A:
undetectable		 2avvA-4jn7A:
16.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJF_A_ADNA2001_1
(235AA LONG
HYPOTHETICAL
BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)		 4jn7 ENOLASE
(Agrobacterium
tumefaciens) 		4 / 7 ARG A 220
TRP A 227
PRO A 197
ALA A 200
 None
 1.05A 2ejfA-4jn7A:
undetectable		 2ejfA-4jn7A:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJF_B_ADNB2002_1
(235AA LONG
HYPOTHETICAL
BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)		 4jn7 ENOLASE
(Agrobacterium
tumefaciens) 		4 / 6 ARG A 220
TRP A 227
PRO A 197
ALA A 200
 None
 1.37A 2ejfB-4jn7A:
undetectable		 2ejfB-4jn7A:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJG_A_ADNA1501_1
(235AA LONG
HYPOTHETICAL
BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)		 4jn7 ENOLASE
(Agrobacterium
tumefaciens) 		4 / 7 ARG A 220
TRP A 227
PRO A 197
ALA A 200
 None
 1.33A 2ejgA-4jn7A:
undetectable		 2ejgA-4jn7A:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4P_A_TPVA300_1
(PROTEASE)		 4jn7 ENOLASE
(Agrobacterium
tumefaciens) 		5 / 11 LEU A  23
ILE A 266
GLY A 270
ILE A  86
VAL A  21
 None
 1.10A 2o4pA-4jn7A:
undetectable		 2o4pA-4jn7A:
14.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD5_A_CHDA701_0
(FERROCHELATASE)		 4jn7 ENOLASE
(Agrobacterium
tumefaciens) 		4 / 8 LEU A  44
PRO A  78
SER A  74
GLY A 270
 None
 1.03A 2qd5A-4jn7A:
undetectable		 2qd5A-4jn7A:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD5_A_CHDA701_0
(FERROCHELATASE)		 4jn7 ENOLASE
(Agrobacterium
tumefaciens) 		4 / 8 LEU A  48
PRO A  78
SER A  74
GLY A 270
 None
 0.88A 2qd5A-4jn7A:
undetectable		 2qd5A-4jn7A:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD5_B_CHDB1103_0
(FERROCHELATASE)		 4jn7 ENOLASE
(Agrobacterium
tumefaciens) 		4 / 8 LEU A  44
PRO A  78
SER A  74
GLY A 270
 None
 1.02A 2qd5B-4jn7A:
undetectable		 2qd5B-4jn7A:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD5_B_CHDB1103_0
(FERROCHELATASE)		 4jn7 ENOLASE
(Agrobacterium
tumefaciens) 		4 / 8 LEU A  48
PRO A  78
SER A  74
GLY A 270
 None
 0.83A 2qd5B-4jn7A:
undetectable		 2qd5B-4jn7A:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QL8_A_BEZA143_0
(PUTATIVE REDOX
PROTEIN)		 4jn7 ENOLASE
(Agrobacterium
tumefaciens) 		4 / 7 ALA A 301
THR A 300
ALA A 299
ARG A  18
 None
 0.96A 2ql8A-4jn7A:
undetectable
2ql8B-4jn7A:
undetectable		 2ql8A-4jn7A:
18.78
2ql8B-4jn7A:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCN_A_CHDA3_0
(FERROCHELATASE,
MITOCHONDRIAL)		 4jn7 ENOLASE
(Agrobacterium
tumefaciens) 		4 / 7 LEU A  44
PRO A  78
SER A  74
GLY A 270
 None
 1.10A 3hcnA-4jn7A:
2.1		 3hcnA-4jn7A:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCN_A_CHDA3_0
(FERROCHELATASE,
MITOCHONDRIAL)		 4jn7 ENOLASE
(Agrobacterium
tumefaciens) 		4 / 7 LEU A  48
PRO A  78
SER A  74
GLY A 270
 None
 0.86A 3hcnA-4jn7A:
2.1		 3hcnA-4jn7A:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCR_A_CHDA424_0
(FERROCHELATASE,
MITOCHONDRIAL)		 4jn7 ENOLASE
(Agrobacterium
tumefaciens) 		4 / 8 LEU A  48
PRO A  78
SER A  74
GLY A 270
 None
 0.85A 3hcrA-4jn7A:
2.0		 3hcrA-4jn7A:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCR_B_CHDB924_0
(FERROCHELATASE,
MITOCHONDRIAL)		 4jn7 ENOLASE
(Agrobacterium
tumefaciens) 		4 / 7 LEU A  48
PRO A  78
SER A  74
GLY A 270
 None
 0.84A 3hcrB-4jn7A:
2.3		 3hcrB-4jn7A:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K37_A_BCZA468_1
(NEURAMINIDASE)		 4jn7 ENOLASE
(Agrobacterium
tumefaciens) 		3 / 3 ASP A  15
ARG A 336
ARG A  18
 None
 1.01A 3k37A-4jn7A:
undetectable		 3k37A-4jn7A:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NT1_A_NPSA5_1
(PROSTAGLANDIN-ENDOPE
ROXIDE SYNTHASE 2)		 4jn7 ENOLASE
(Agrobacterium
tumefaciens) 		5 / 12 LEU A  23
LEU A  70
VAL A  21
GLY A  33
ALA A  88
 None
 1.09A 3nt1A-4jn7A:
undetectable		 3nt1A-4jn7A:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O9M_B_BEZB999_0
(CHOLINESTERASE)		 4jn7 ENOLASE
(Agrobacterium
tumefaciens) 		4 / 6 GLY A 271
GLY A 270
SER A 273
LEU A  70
 None
 0.71A 3o9mB-4jn7A:
undetectable		 3o9mB-4jn7A:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QG2_B_CP6B709_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 4jn7 ENOLASE
(Agrobacterium
tumefaciens) 		5 / 11 ILE A 186
ALA A 147
PHE A 136
ILE A 333
LEU A 150
 None
 1.31A 3qg2B-4jn7A:
undetectable		 3qg2B-4jn7A:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RR3_C_FLRC700_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4jn7 ENOLASE
(Agrobacterium
tumefaciens) 		5 / 12 LEU A  23
LEU A  70
VAL A  21
GLY A  33
ALA A  88
 None
 1.07A 3rr3C-4jn7A:
undetectable		 3rr3C-4jn7A:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RR3_D_FLRD700_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4jn7 ENOLASE
(Agrobacterium
tumefaciens) 		5 / 12 LEU A  23
LEU A  70
VAL A  21
GLY A  33
ALA A  88
 None
 1.07A 3rr3D-4jn7A:
undetectable		 3rr3D-4jn7A:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U40_E_ADNE251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4jn7 ENOLASE
(Agrobacterium
tumefaciens) 		5 / 12 ARG A   7
VAL A 365
GLU A 366
MET A 367
ASP A  95
 None
 1.33A 3u40D-4jn7A:
undetectable
3u40E-4jn7A:
undetectable		 3u40D-4jn7A:
21.75
3u40E-4jn7A:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J5J_B_478B401_2
(PROTEASE)		 4jn7 ENOLASE
(Agrobacterium
tumefaciens) 		5 / 10 VAL A 268
GLY A 271
ILE A 272
PRO A 291
VAL A 289
 None
 1.05A 4j5jB-4jn7A:
undetectable		 4j5jB-4jn7A:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLR_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 4jn7 ENOLASE
(Agrobacterium
tumefaciens) 		4 / 8 LEU A  48
PRO A  78
SER A  74
GLY A 270
 None
 0.97A 4klrB-4jn7A:
undetectable		 4klrB-4jn7A:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KR3_A_GLYA701_0
(GLYCINE--TRNA LIGASE)		 4jn7 ENOLASE
(Agrobacterium
tumefaciens) 		4 / 6 ARG A 382
GLU A 242
GLU A 217
SER A 243
 LMR  A 402 (-4.0A)
LMR  A 402 ( 2.6A)
None
None
 1.50A 4kr3A-4jn7A:
undetectable		 4kr3A-4jn7A:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LMN_A_EUIA503_2
(DUAL SPECIFICITY
MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE 1)		 4jn7 ENOLASE
(Agrobacterium
tumefaciens) 		3 / 3 ASP A 351
VAL A 117
ASN A 140
 None
None
CL  A 411 (-3.2A)
 0.80A 4lmnA-4jn7A:
undetectable		 4lmnA-4jn7A:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_A_ADNA501_2
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 4jn7 ENOLASE
(Agrobacterium
tumefaciens) 		3 / 3 PRO A  45
LEU A  48
HIS A  91
 None
 0.73A 4pevA-4jn7A:
undetectable		 4pevA-4jn7A:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTR_A_SAMA301_0
(DNA ADENINE
METHYLASE)		 4jn7 ENOLASE
(Agrobacterium
tumefaciens) 		5 / 11 GLY A 390
ASP A 156
ILE A 157
PRO A 385
TYR A 392
 None
None
EDO  A 404 ( 4.1A)
None
None
 1.45A 4rtrA-4jn7A:
undetectable		 4rtrA-4jn7A:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDN_G_EVPG2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 4jn7 ENOLASE
(Agrobacterium
tumefaciens) 		4 / 6 SER A 273
GLU A 274
GLY A  31
GLY A  33
 None
 0.73A 5cdnA-4jn7A:
undetectable
5cdnB-4jn7A:
undetectable		 5cdnA-4jn7A:
21.15
5cdnB-4jn7A:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDN_N_EVPN2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 4jn7 ENOLASE
(Agrobacterium
tumefaciens) 		4 / 6 SER A 273
GLU A 274
GLY A  31
GLY A  33
 None
 0.73A 5cdnR-4jn7A:
undetectable
5cdnS-4jn7A:
undetectable		 5cdnR-4jn7A:
21.15
5cdnS-4jn7A:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGI_A_ZITA402_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 4jn7 ENOLASE
(Agrobacterium
tumefaciens) 		5 / 12 MET A 275
ILE A 266
ALA A 282
PHE A 214
TYR A 120
 None
 1.25A 5igiA-4jn7A:
undetectable		 5igiA-4jn7A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_B_1GNB603_1
(PHIAB6 TAILSPIKE)		 4jn7 ENOLASE
(Agrobacterium
tumefaciens) 		3 / 3 VAL A 268
GLU A 216
GLU A 217
 None
NA  A 401 (-3.2A)
None
 0.91A 5jsdB-4jn7A:
undetectable
5jsdC-4jn7A:
undetectable		 5jsdB-4jn7A:
18.01
5jsdC-4jn7A:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR2_C_ROCC101_2
(PROTEASE PR5-SQV)		 4jn7 ENOLASE
(Agrobacterium
tumefaciens) 		5 / 9 LEU A  23
ILE A 266
GLY A 270
ILE A  86
VAL A  21
 None
 1.16A 5kr2D-4jn7A:
undetectable		 5kr2D-4jn7A:
17.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CLX_A_SAMA401_0
(O-METHYLTRANSFERASE)		 4jn7 ENOLASE
(Agrobacterium
tumefaciens) 		5 / 12 ASP A  13
GLY A 296
ARG A 319
VAL A 302
ASP A 265
 None
 1.26A 6clxA-4jn7A:
undetectable		 6clxA-4jn7A:
23.65