SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4jng'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3THR_A_C2FA1100_1
(GLYCINE
N-METHYLTRANSFERASE)		 4jng NUCLEOCAPSID PROTEIN
(Sathuperi
orthobunyavirus) 		3 / 3 LEU A 168
HIS A 165
MET A 164
 None
 0.96A 3thrD-4jngA:
undetectable		 3thrD-4jngA:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5Q_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 4jng NUCLEOCAPSID PROTEIN
(Sathuperi
orthobunyavirus) 		4 / 6 ASP A 156
ALA A 154
THR A 139
TYR A 158
 None
 1.38A 4w5qA-4jngA:
undetectable		 4w5qA-4jngA:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5R_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 4jng NUCLEOCAPSID PROTEIN
(Sathuperi
orthobunyavirus) 		4 / 6 ASP A 156
ALA A 154
THR A 139
TYR A 158
 None
 1.32A 4w5rA-4jngA:
undetectable		 4w5rA-4jngA:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5T_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 4jng NUCLEOCAPSID PROTEIN
(Sathuperi
orthobunyavirus) 		4 / 6 ASP A 156
ALA A 154
THR A 139
TYR A 158
 None
 1.39A 4w5tA-4jngA:
undetectable		 4w5tA-4jngA:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4C_A_IPHA906_0
(PROTEIN ARGONAUTE-2)		 4jng NUCLEOCAPSID PROTEIN
(Sathuperi
orthobunyavirus) 		4 / 6 ASP A 156
ALA A 154
THR A 139
TYR A 158
 None
 1.40A 4z4cA-4jngA:
undetectable		 4z4cA-4jngA:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4F_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 4jng NUCLEOCAPSID PROTEIN
(Sathuperi
orthobunyavirus) 		4 / 6 ASP A 156
ALA A 154
THR A 139
TYR A 158
 None
 1.38A 4z4fA-4jngA:
undetectable		 4z4fA-4jngA:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4G_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 4jng NUCLEOCAPSID PROTEIN
(Sathuperi
orthobunyavirus) 		4 / 5 ASP A 156
ALA A 154
THR A 139
TYR A 158
 None
 1.39A 4z4gA-4jngA:
undetectable		 4z4gA-4jngA:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4I_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 4jng NUCLEOCAPSID PROTEIN
(Sathuperi
orthobunyavirus) 		4 / 6 ASP A 156
ALA A 154
THR A 139
TYR A 158
 None
 1.43A 4z4iA-4jngA:
undetectable		 4z4iA-4jngA:
13.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H8T_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 4jng NUCLEOCAPSID PROTEIN
(Sathuperi
orthobunyavirus) 		5 / 12 PHE A  44
ALA A 145
ILE A  28
TYR A  99
LEU A  35
 None
 1.04A 5h8tA-4jngA:
undetectable		 5h8tA-4jngA:
16.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNA_A_ACTA307_0
(THIOREDOXIN
REDUCTASE)		 4jng NUCLEOCAPSID PROTEIN
(Sathuperi
orthobunyavirus) 		3 / 3 ARG A 102
LYS A 109
TYR A 138
 None
 0.93A 6gnaA-4jngA:
undetectable		 6gnaA-4jngA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNB_A_ACTA307_0
(THIOREDOXIN
REDUCTASE)		 4jng NUCLEOCAPSID PROTEIN
(Sathuperi
orthobunyavirus) 		3 / 3 ARG A 102
LYS A 109
TYR A 138
 None
 0.93A 6gnbA-4jngA:
undetectable		 6gnbA-4jngA:
19.86