SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4jnh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_A_FFOA1293_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 4jnh GAG POLYPROTEIN
(Simian
foamy
virus) 		3 / 3 GLU A  49
TYR A 123
PHE A  51
 None
 0.92A 1eqbB-4jnhA:
undetectable		 1eqbB-4jnhA:
17.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_B_FFOB2293_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 4jnh GAG POLYPROTEIN
(Simian
foamy
virus) 		3 / 3 GLU A  49
TYR A 123
PHE A  51
 None
 0.92A 1eqbA-4jnhA:
undetectable		 1eqbA-4jnhA:
17.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_C_FFOC3293_2
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 4jnh GAG POLYPROTEIN
(Simian
foamy
virus) 		3 / 3 GLU A  49
TYR A 123
PHE A  51
 None
 0.92A 1eqbD-4jnhA:
undetectable		 1eqbD-4jnhA:
17.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_D_FFOD4293_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 4jnh GAG POLYPROTEIN
(Simian
foamy
virus) 		3 / 3 GLU A  49
TYR A 123
PHE A  51
 None
 0.93A 1eqbC-4jnhA:
undetectable		 1eqbC-4jnhA:
17.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HS2_B_017B203_1
(PROTEASE)		 4jnh GAG POLYPROTEIN
(Simian
foamy
virus) 		4 / 6 PRO A 103
LEU A 100
ARG A  50
GLY A  43
 None
 1.05A 2hs2B-4jnhA:
undetectable		 2hs2B-4jnhA:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_B_SVRB512_2
(PHOSPHOLIPASE A2)		 4jnh GAG POLYPROTEIN
(Simian
foamy
virus) 		4 / 7 VAL A  18
ILE A  36
GLY A  37
ARG A  39
 None
 0.87A 3bjwB-4jnhA:
undetectable		 3bjwB-4jnhA:
16.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF509_3
(PHOSPHOLIPASE A2)		 4jnh GAG POLYPROTEIN
(Simian
foamy
virus) 		4 / 7 VAL A  18
ILE A  36
GLY A  37
ARG A  39
 None
 0.86A 3bjwF-4jnhA:
undetectable		 3bjwF-4jnhA:
16.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_H_SVRH511_3
(PHOSPHOLIPASE A2)		 4jnh GAG POLYPROTEIN
(Simian
foamy
virus) 		4 / 7 VAL A  18
ILE A  36
GLY A  37
ARG A  39
 None
 0.87A 3bjwH-4jnhA:
undetectable		 3bjwH-4jnhA:
16.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 4jnh GAG POLYPROTEIN
(Simian
foamy
virus) 		5 / 9 THR A  82
ALA A  77
ALA A 113
VAL A  35
GLY A  37
 None
 1.23A 4qvnK-4jnhA:
undetectable
4qvnL-4jnhA:
undetectable		 4qvnK-4jnhA:
19.28
4qvnL-4jnhA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 4jnh GAG POLYPROTEIN
(Simian
foamy
virus) 		5 / 9 THR A  82
ALA A  77
ALA A 113
VAL A  35
GLY A  37
 None
 1.23A 4qvnY-4jnhA:
undetectable
4qvnZ-4jnhA:
undetectable		 4qvnY-4jnhA:
19.28
4qvnZ-4jnhA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CR1_A_T44A201_1
(TRANSTHYRETIN)		 4jnh GAG POLYPROTEIN
(Simian
foamy
virus) 		4 / 5 LEU A 100
ALA A  96
LEU A  93
VAL A  14
 None
 1.19A 5cr1A-4jnhA:
undetectable		 5cr1A-4jnhA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NY7_A_NCAA303_0
(AMIDASE)		 4jnh GAG POLYPROTEIN
(Simian
foamy
virus) 		4 / 6 GLY A 110
PRO A 111
GLU A  49
SER A 126
 None
 1.09A 5ny7A-4jnhA:
undetectable		 5ny7A-4jnhA:
22.90