SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4jnj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KOT_A_ANWA99_0
(PROTEIN S100-A13)		 4jnj STREPTAVIDIN/RHIZAVI
DIN HYBRID
(Streptomyces
avidinii) 		4 / 7 VAL A  31
THR A  30
PHE A  29
THR A  28
 None
 1.27A 2kotA-4jnjA:
undetectable		 2kotA-4jnjA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KOT_B_ANWB99_0
(PROTEIN S100-A13)		 4jnj STREPTAVIDIN/RHIZAVI
DIN HYBRID
(Streptomyces
avidinii) 		4 / 8 VAL A  31
THR A  30
PHE A  29
THR A  28
 None
 1.24A 2kotB-4jnjA:
undetectable		 2kotB-4jnjA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UZ2_A_ACTA1123_0
(XENAVIDIN)		 4jnj STREPTAVIDIN/RHIZAVI
DIN HYBRID
(Streptomyces
avidinii) 		4 / 7 ASN A  23
SER A  27
TYR A  43
TRP A  92
 BTN  A 201 (-3.4A)
BTN  A 201 (-2.6A)
BTN  A 201 (-4.6A)
BTN  A 201 ( 4.8A)
 0.14A 2uz2A-4jnjA:
14.8		 2uz2A-4jnjA:
28.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_D_SORD1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 4jnj STREPTAVIDIN/RHIZAVI
DIN HYBRID
(Streptomyces
avidinii) 		4 / 6 LYS A  12
GLY A  34
GLY A  37
ASP A  36
 ZN  A 203 ( 3.8A)
ZN  A 204 ( 4.9A)
None
ZN  A 204 (-2.6A)
 0.93A 5a06D-4jnjA:
undetectable		 5a06D-4jnjA:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4jnj STREPTAVIDIN/RHIZAVI
DIN HYBRID
(Streptomyces
avidinii) 		4 / 7 ILE A  17
ARG A  59
THR A  57
LEU A  56
 None
 0.97A 5xdqA-4jnjA:
undetectable
5xdqJ-4jnjA:
undetectable		 5xdqA-4jnjA:
11.29
5xdqJ-4jnjA:
21.00