SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4jnt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B0W_A_DGXA1_2
(NUCLEAR RECEPTOR
ROR-GAMMA)		 4jnt ENVELOPE
GLYCOPROTEIN E2
(Pestivirus
A) 		3 / 3 TRP A 879
VAL A 830
ARG A 846
 NAG  A2401 (-3.6A)
None
None
 0.93A 3b0wA-4jntA:
undetectable		 3b0wA-4jntA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EAH_F_ACTF402_0
(ACTIN, ALPHA
SKELETAL MUSCLE)		 4jnt ENVELOPE
GLYCOPROTEIN E2
(Pestivirus
A) 		3 / 3 PHE A 791
ASP A 789
ARG A 850
 None
 0.72A 4eahF-4jntA:
undetectable		 4eahF-4jntA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EAH_G_ACTG401_0
(ACTIN, ALPHA
SKELETAL MUSCLE)		 4jnt ENVELOPE
GLYCOPROTEIN E2
(Pestivirus
A) 		3 / 3 PHE A 791
ASP A 789
ARG A 850
 None
 0.72A 4eahG-4jntA:
undetectable		 4eahG-4jntA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWZ_B_BEZB301_0
(14-3-3 PROTEIN
ZETA/DELTA)		 4jnt ENVELOPE
GLYCOPROTEIN E2
(Pestivirus
A) 		3 / 3 MET A1011
GLN A1009
ARG A1003
 None
 1.07A 5ewzB-4jntA:
undetectable		 5ewzB-4jntA:
20.59