SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4jo6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2UZ2_A_ACTA1123_0
(XENAVIDIN)		 4jo6 STREPTAVIDIN
(Streptomyces
avidinii) 		5 / 7 ASN A  23
LEU A  25
SER A  27
TYR A  43
TRP A  92
 None
 0.70A 2uz2A-4jo6A:
15.6		 2uz2A-4jo6A:
32.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2UZ2_A_ACTA1123_0
(XENAVIDIN)		 4jo6 STREPTAVIDIN
SBP-TAG
(Streptomyces
avidinii;
) 		5 / 7 ASN A  23
LEU A  25
SER A  27
TYR A  43
VAL Y  13
 None
 1.30A 2uz2A-4jo6A:
15.6		 2uz2A-4jo6A:
32.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SI7_A_ACTA4_0
(CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR)		 4jo6 STREPTAVIDIN
(Streptomyces
avidinii) 		4 / 4 LEU A  73
GLY A  74
GLY A  94
THR A 106
 None
 0.93A 3si7A-4jo6A:
undetectable		 3si7A-4jo6A:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EQ4_B_SALB601_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 4jo6 STREPTAVIDIN
(Streptomyces
avidinii) 		4 / 8 THR A  71
ILE A  17
VAL A  31
GLY A  74
 None
 0.81A 4eq4B-4jo6A:
undetectable		 4eq4B-4jo6A:
14.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5N8J_E_DVAE7_0
(GLY-DTY-GLY-DLE-DAL-
DSG-DVA-DAS-DGL-DSN-
DSN-GLY
STREPTAVIDIN)		 4jo6 STREPTAVIDIN
(Streptomyces
avidinii) 		3 / 3 TYR A  43
SER A  45
TRP A  79
 None
 0.41A 5n8jB-4jo6A:
23.2		 5n8jB-4jo6A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5N8J_O_DVAO7_0
(GLY-DTY-GLY-DLE-DAL-
DSG-DVA-DAS-DGL-DSN-
DSN-GLY
STREPTAVIDIN)		 4jo6 STREPTAVIDIN
(Streptomyces
avidinii) 		3 / 3 TYR A  43
SER A  45
TRP A  79
 None
 0.44A 5n8jA-4jo6A:
23.5		 5n8jA-4jo6A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5N8J_P_DVAP5_0
(GLY-DTY-GLY-DLE-DAL-
DSG-DVA-DAS-DGL-DSN-
DSN-GLY
STREPTAVIDIN)		 4jo6 STREPTAVIDIN
(Streptomyces
avidinii) 		3 / 3 TYR A  43
SER A  45
TRP A  79
 None
 0.45A 5n8jD-4jo6A:
23.1		 5n8jD-4jo6A:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C71_B_NCTB501_1
(AMINE OXIDASE)		 4jo6 STREPTAVIDIN
(Streptomyces
avidinii) 		4 / 8 TYR A  43
TRP A  79
THR A  90
ASN A  23
 None
 1.22A 6c71B-4jo6A:
undetectable		 6c71B-4jo6A:
20.13