SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4jof'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2KAW_A_SUZA91_1
(SEGMENT POLARITY
PROTEIN DISHEVELLED
HOMOLOG DVL-1)		 4jof GOLGI-ASSOCIATED PDZ
AND COILED-COIL
MOTIF-CONTAINING
PROTEIN
(Homo
sapiens) 		5 / 11 LEU A 299
GLY A 300
ILE A 301
SER A 302
ILE A 303
 None
 0.64A 2kawA-4jofA:
12.5		 2kawA-4jofA:
34.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9V_B_DXCB323_0
(INVASIN IPAD)		 4jof GOLGI-ASSOCIATED PDZ
AND COILED-COIL
MOTIF-CONTAINING
PROTEIN
(Homo
sapiens) 		4 / 7 ILE A 303
VAL A 353
LEU A 356
SER A 357
 None
 0.56A 3r9vA-4jofA:
undetectable
3r9vB-4jofA:
undetectable		 3r9vA-4jofA:
16.91
3r9vB-4jofA:
16.91