SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4jon'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_B_SC2B1290_1
(FICOLIN-2)		 4jon CENTROSOMAL PROTEIN
OF 170 KDA
(Homo
sapiens) 		4 / 8 SER A  11
LEU A  95
SER A  10
ARG A  88
 None
 0.84A 2j2pA-4jonA:
undetectable
2j2pB-4jonA:
undetectable		 2j2pA-4jonA:
21.20
2j2pB-4jonA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZN_A_SAMA401_0
(UNCHARACTERIZED
PROTEIN MJ0883)		 4jon CENTROSOMAL PROTEIN
OF 170 KDA
(Homo
sapiens) 		5 / 12 ARG A  88
PHE A  89
GLY A  65
ASN A  64
VAL A  25
 None
 1.28A 2zznA-4jonA:
undetectable		 2zznA-4jonA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OT2_A_NPSA601_1
(SERUM ALBUMIN)		 4jon CENTROSOMAL PROTEIN
OF 170 KDA
(Homo
sapiens) 		5 / 12 VAL A  39
GLY A  90
SER A  36
LEU A  34
SER A  10
 None
 1.34A 4ot2A-4jonA:
undetectable		 4ot2A-4jonA:
13.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4jon CENTROSOMAL PROTEIN
OF 170 KDA
(Homo
sapiens) 		3 / 3 TYR A  91
ARG A  88
THR A  66
 None
 0.93A 5z84J-4jonA:
undetectable		 5z84J-4jonA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CI6_A_NBOA606_1
(SERUM ALBUMIN)		 4jon CENTROSOMAL PROTEIN
OF 170 KDA
(Homo
sapiens) 		5 / 12 VAL A  39
GLY A  90
SER A  36
LEU A  34
SER A  10
 None
 1.37A 6ci6A-4jonA:
undetectable		 6ci6A-4jonA:
21.14