SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4jpq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_A_DVAA6_0
(GRAMICIDIN A)		 4jpq UNCHARACTERIZED
PROTEIN
(Bacteroides
uniformis) 		3 / 3 ALA A 101
VAL A 103
TRP A 185
 None
 0.96A 1av2A-4jpqA:
undetectable
1av2B-4jpqA:
undetectable		 1av2A-4jpqA:
8.11
1av2B-4jpqA:
8.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_A_DVAA6_0
(GRAMICIDIN A)		 4jpq UNCHARACTERIZED
PROTEIN
(Bacteroides
uniformis) 		3 / 3 ALA A 101
VAL A 103
TRP A 185
 None
 0.82A 1gmkA-4jpqA:
undetectable
1gmkB-4jpqA:
undetectable		 1gmkA-4jpqA:
8.11
1gmkB-4jpqA:
8.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_C_DVAC6_0
(GRAMICIDIN A)		 4jpq UNCHARACTERIZED
PROTEIN
(Bacteroides
uniformis) 		3 / 3 ALA A 101
VAL A 103
TRP A 185
 None
 0.77A 1gmkC-4jpqA:
undetectable
1gmkD-4jpqA:
undetectable		 1gmkC-4jpqA:
8.11
1gmkD-4jpqA:
8.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I00_B_D16B409_1
(THYMIDYLATE SYNTHASE)		 4jpq UNCHARACTERIZED
PROTEIN
(Bacteroides
uniformis) 		5 / 9 PHE A 122
ILE A 191
ASP A 110
LEU A 143
PHE A 135
 None
 1.34A 1i00B-4jpqA:
undetectable		 1i00B-4jpqA:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_A_DVAA6_0
(GRAMICIDIN D)		 4jpq UNCHARACTERIZED
PROTEIN
(Bacteroides
uniformis) 		3 / 3 ALA A 101
VAL A 103
TRP A 185
 None
 0.96A 1w5uA-4jpqA:
undetectable
1w5uB-4jpqA:
undetectable		 1w5uA-4jpqA:
8.11
1w5uB-4jpqA:
8.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_B_DVAB6_0
(GRAMICIDIN D)		 4jpq UNCHARACTERIZED
PROTEIN
(Bacteroides
uniformis) 		3 / 3 TRP A 185
ALA A 101
VAL A 103
 None
 0.94A 1w5uA-4jpqA:
undetectable
1w5uB-4jpqA:
undetectable		 1w5uA-4jpqA:
8.11
1w5uB-4jpqA:
8.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KUH_A_HLTA150_1
(CALMODULIN)		 4jpq UNCHARACTERIZED
PROTEIN
(Bacteroides
uniformis) 		4 / 6 LEU A 143
MET A 189
LEU A 187
GLU A 121
 None
None
None
CXS  A 301 ( 4.7A)
 1.13A 2kuhA-4jpqA:
undetectable		 2kuhA-4jpqA:
13.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KUH_A_HLTA150_1
(CALMODULIN)		 4jpq UNCHARACTERIZED
PROTEIN
(Bacteroides
uniformis) 		4 / 6 LEU A 143
MET A 189
LEU A 187
GLU A 136
 None
None
None
CXS  A 301 ( 4.8A)
 1.13A 2kuhA-4jpqA:
undetectable		 2kuhA-4jpqA:
13.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2TSR_C_D16C509_1
(THYMIDYLATE SYNTHASE)		 4jpq UNCHARACTERIZED
PROTEIN
(Bacteroides
uniformis) 		5 / 10 PHE A 122
ILE A 191
ASP A 110
LEU A 143
PHE A 135
 None
 1.46A 2tsrC-4jpqA:
undetectable		 2tsrC-4jpqA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_D_DVAD6_0
(GRAMICIDIN D)		 4jpq UNCHARACTERIZED
PROTEIN
(Bacteroides
uniformis) 		3 / 3 TRP A 185
ALA A 101
VAL A 103
 None
 0.96A 3l8lC-4jpqA:
undetectable
3l8lD-4jpqA:
undetectable		 3l8lC-4jpqA:
8.11
3l8lD-4jpqA:
6.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DXU_A_ACAA711_1
(LACTOTRANSFERRIN)		 4jpq UNCHARACTERIZED
PROTEIN
(Bacteroides
uniformis) 		4 / 6 GLY A 211
VAL A 124
GLY A 128
GLU A 127
 None
None
None
SO4  A 304 ( 4.2A)
 0.89A 4dxuA-4jpqA:
undetectable		 4dxuA-4jpqA:
24.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EB4_C_D16C402_1
(THYMIDYLATE SYNTHASE)		 4jpq UNCHARACTERIZED
PROTEIN
(Bacteroides
uniformis) 		5 / 9 PHE A 122
ILE A 191
ASP A 110
LEU A 143
PHE A 135
 None
 1.33A 4eb4C-4jpqA:
undetectable		 4eb4C-4jpqA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EB4_D_D16D402_1
(THYMIDYLATE SYNTHASE)		 4jpq UNCHARACTERIZED
PROTEIN
(Bacteroides
uniformis) 		5 / 10 PHE A 122
ILE A 191
ASP A 110
LEU A 143
PHE A 135
 None
 1.42A 4eb4D-4jpqA:
undetectable		 4eb4D-4jpqA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KIC_B_SAMB401_1
(METHYLTRANSFERASE
MPPJ)		 4jpq UNCHARACTERIZED
PROTEIN
(Bacteroides
uniformis) 		3 / 3 ARG A 167
ASP A 117
ASP A 218
 None
None
CXS  A 301 ( 4.5A)
 0.87A 4kicB-4jpqA:
undetectable		 4kicB-4jpqA:
21.39