SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4jq6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1FO4_B_SALB4005_1 (XANTHINE DEHYDROGENASE)	4jq6	PROTEORHODOPSIN (uncultured bacterium)	4 / 7	PHE A 55 THR A 26 VAL A 27 ALA A 20	None	0.94A	1fo4B-4jq6A: undetectable	1fo4B-4jq6A: 10.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ZQ9_A_SAMA4000_0 (PROBABLE DIMETHYLADENOSINE TRANSFERASE)	4jq6	PROTEORHODOPSIN (uncultured bacterium)	5 / 12	ILE A 139 GLY A 137 LEU A 114 VAL A 84 ILE A 88	None RET A 301 (-4.1A) None RET A 301 (-4.3A) None	1.21A	1zq9A-4jq6A: undetectable	1zq9A-4jq6A: 21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3T3S_F_9PLF1_1 (CYTOCHROME P450 2A13)	4jq6	PROTEORHODOPSIN (uncultured bacterium)	4 / 8	PHE A 15 ALA A 18 ASN A 206 THR A 83	None None None RET A 301 (-4.3A)	0.96A	3t3sF-4jq6A: undetectable	3t3sF-4jq6A: 17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5IKT_A_TLFA601_1 (PROSTAGLANDIN G/H SYNTHASE 2)	4jq6	PROTEORHODOPSIN (uncultured bacterium)	3 / 3	LEU A 210 TYR A 58 SER A 14	None	0.79A	5iktA-4jq6A: undetectable	5iktA-4jq6A: 18.44

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1FO4_B_SALB4005_1","XANTHINE DEHYDROGENASE","4jq6","PROTEORHODOPSIN","uncultured bacterium",4,"PHE A  55;THR A  26;VAL A  27;ALA A  20","None","0.94A","1fo4B-4jq6A:undetectable","1fo4B-4jq6A:10.52"],["1ZQ9_A_SAMA4000_0","PROBABLE DIMETHYLADENOSINE TRANSFERASE","4jq6","PROTEORHODOPSIN","uncultured bacterium",5,"ILE A 139;GLY A 137;LEU A 114;VAL A  84;ILE A  88","None;RET A 301 (-4.1A);None;RET A 301 (-4.3A);None","1.21A","1zq9A-4jq6A:undetectable","1zq9A-4jq6A:21.50"],["3T3S_F_9PLF1_1","CYTOCHROME P450 2A13","4jq6","PROTEORHODOPSIN","uncultured bacterium",4,"PHE A  15;ALA A  18;ASN A 206;THR A  83","None;None;None;RET A 301 (-4.3A)","0.96A","3t3sF-4jq6A:undetectable","3t3sF-4jq6A:17.65"],["5IKT_A_TLFA601_1","PROSTAGLANDIN G\/H SYNTHASE 2","4jq6","PROTEORHODOPSIN","uncultured bacterium",3,"LEU A 210;TYR A  58;SER A  14","None","0.79A","5iktA-4jq6A:undetectable","5iktA-4jq6A:18.44"]]