SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4jq9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C6Z_B_ROCB505_1
(PROTEIN (PROTEASE))		 4jq9 DIHYDROLIPOYL
DEHYDROGENASE
(Escherichia
coli) 		5 / 12 GLY A  15
ALA A  14
VAL A 112
THR A  32
ILE A  34
 FAD  A 512 (-3.4A)
None
None
None
None
 0.85A 1c6zA-4jq9A:
undetectable		 1c6zA-4jq9A:
11.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C6Z_B_ROCB505_2
(PROTEIN (PROTEASE))		 4jq9 DIHYDROLIPOYL
DEHYDROGENASE
(Escherichia
coli) 		5 / 12 GLY A  15
ALA A  14
VAL A 112
THR A  32
ILE A  34
 FAD  A 512 (-3.4A)
None
None
None
None
 0.85A 1c6zB-4jq9A:
undetectable		 1c6zB-4jq9A:
11.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_B_ADNB602_2
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 4jq9 DIHYDROLIPOYL
DEHYDROGENASE
(Escherichia
coli) 		4 / 5 THR A 120
THR A 124
GLU A   4
THR A   3
 None
SO4  A 502 (-3.7A)
None
None
 1.41A 1d4fB-4jq9A:
4.1		 1d4fB-4jq9A:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D8C_A_SORA4000_0
(MALATE SYNTHASE G)		 4jq9 DIHYDROLIPOYL
DEHYDROGENASE
(Escherichia
coli) 		3 / 3 GLN A 151
HIS A 157
PRO A 153
 None
 0.97A 1d8cA-4jq9A:
undetectable		 1d8cA-4jq9A:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG3_A_ADNA500_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)		 4jq9 DIHYDROLIPOYL
DEHYDROGENASE
(Escherichia
coli) 		5 / 11 GLY A  18
GLY A  13
ILE A 143
LEU A  12
GLY A 328
 None
FAD  A 512 (-3.1A)
None
FAD  A 512 (-4.7A)
None
 0.84A 1jg3A-4jq9A:
2.8		 1jg3A-4jq9A:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG3_B_ADNB550_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)		 4jq9 DIHYDROLIPOYL
DEHYDROGENASE
(Escherichia
coli) 		5 / 11 GLY A  18
GLY A  13
ILE A 143
LEU A  12
GLY A 328
 None
FAD  A 512 (-3.1A)
None
FAD  A 512 (-4.7A)
None
 0.82A 1jg3B-4jq9A:
3.3		 1jg3B-4jq9A:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K6C_B_MK1B902_2
(POL POLYPROTEIN)		 4jq9 DIHYDROLIPOYL
DEHYDROGENASE
(Escherichia
coli) 		5 / 12 GLY A 182
GLY A 191
ILE A 201
THR A 223
VAL A 210
 None
 0.93A 1k6cB-4jq9A:
undetectable		 1k6cB-4jq9A:
12.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KGL_A_RTLA175_0
(CELLULAR
RETINOL-BINDING
PROTEIN TYPE I)		 4jq9 DIHYDROLIPOYL
DEHYDROGENASE
(Escherichia
coli) 		5 / 12 LEU A 268
ALA A 168
PRO A  52
GLY A 187
ILE A 186
 None
None
None
None
SO4  A 501 (-3.7A)
 1.26A 1kglA-4jq9A:
undetectable		 1kglA-4jq9A:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SDU_B_MK1B902_1
(PROTEASE RETROPEPSIN)		 4jq9 DIHYDROLIPOYL
DEHYDROGENASE
(Escherichia
coli) 		5 / 11 ALA A 428
GLY A 411
GLY A 410
ILE A 409
ILE A 438
 None
 1.04A 1sduA-4jq9A:
undetectable		 1sduA-4jq9A:
12.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SDV_B_MK1B902_1
(PROTEASE RETROPEPSIN)		 4jq9 DIHYDROLIPOYL
DEHYDROGENASE
(Escherichia
coli) 		5 / 10 ALA A 428
GLY A 411
GLY A 410
ILE A 409
ILE A 438
 None
 0.93A 1sdvA-4jq9A:
undetectable		 1sdvA-4jq9A:
12.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BYO_A_LNLA1217_1
(LIPOPROTEIN LPPX)		 4jq9 DIHYDROLIPOYL
DEHYDROGENASE
(Escherichia
coli) 		4 / 4 VAL A 221
LEU A 399
ILE A 425
LEU A 421
 None
 0.80A 2byoA-4jq9A:
undetectable		 2byoA-4jq9A:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FCN_B_DVAB35_0
(UBIQUITIN)		 4jq9 DIHYDROLIPOYL
DEHYDROGENASE
(Escherichia
coli) 		4 / 6 LEU A 234
GLN A 209
ILE A 211
PRO A 212
 None
 1.04A 2fcnA-4jq9A:
undetectable
2fcnB-4jq9A:
undetectable		 2fcnA-4jq9A:
10.41
2fcnB-4jq9A:
10.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QBL_A_CAMA517_0
(CYTOCHROME P450-CAM)		 4jq9 DIHYDROLIPOYL
DEHYDROGENASE
(Escherichia
coli) 		4 / 7 LEU A  57
VAL A 193
THR A 192
VAL A 180
 GOL  A 505 (-3.9A)
None
None
None
 0.93A 2qblA-4jq9A:
undetectable		 2qblA-4jq9A:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZIF_B_SAMB298_0
(PUTATIVE
MODIFICATION
METHYLASE)		 4jq9 DIHYDROLIPOYL
DEHYDROGENASE
(Escherichia
coli) 		5 / 12 ALA A 266
GLY A 191
THR A 192
LEU A 179
VAL A 203
 None
 1.10A 2zifB-4jq9A:
undetectable		 2zifB-4jq9A:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKP_B_478B200_2
(PROTEASE)		 4jq9 DIHYDROLIPOYL
DEHYDROGENASE
(Escherichia
coli) 		6 / 10 ALA A 428
VAL A 452
GLY A 410
ILE A 409
ALA A 456
ILE A 438
 None
 1.21A 3ekpB-4jq9A:
undetectable		 3ekpB-4jq9A:
12.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKP_C_478C200_1
(PROTEASE)		 4jq9 DIHYDROLIPOYL
DEHYDROGENASE
(Escherichia
coli) 		5 / 10 ALA A 428
GLY A 410
ILE A 409
ALA A 456
ILE A 438
 None
 1.00A 3ekpC-4jq9A:
undetectable		 3ekpC-4jq9A:
12.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKT_B_017B200_2
(PROTEASE)		 4jq9 DIHYDROLIPOYL
DEHYDROGENASE
(Escherichia
coli) 		5 / 9 ALA A 428
GLY A 411
ILE A 400
ALA A 456
ILE A 438
 None
 0.89A 3ektB-4jq9A:
undetectable		 3ektB-4jq9A:
12.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKT_B_017B200_2
(PROTEASE)		 4jq9 DIHYDROLIPOYL
DEHYDROGENASE
(Escherichia
coli) 		6 / 9 ALA A 428
VAL A 452
GLY A 410
ILE A 409
ALA A 456
ILE A 438
 None
 1.20A 3ektB-4jq9A:
undetectable		 3ektB-4jq9A:
12.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKX_B_1UNB201_2
(PROTEASE)		 4jq9 DIHYDROLIPOYL
DEHYDROGENASE
(Escherichia
coli) 		5 / 11 ALA A 428
VAL A 452
GLY A 410
ILE A 409
ILE A 438
 None
 0.97A 3ekxB-4jq9A:
undetectable		 3ekxB-4jq9A:
13.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MSS_D_STID1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 4jq9 DIHYDROLIPOYL
DEHYDROGENASE
(Escherichia
coli) 		4 / 6 VAL A 360
VAL A 325
ILE A 347
MET A 431
 None
 0.86A 3mssD-4jq9A:
undetectable		 3mssD-4jq9A:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N62_A_MTLA870_0
(NITRIC OXIDE
SYNTHASE)		 4jq9 DIHYDROLIPOYL
DEHYDROGENASE
(Escherichia
coli) 		4 / 8 SER A 147
ARG A 273
GLN A 151
ASN A 276
 None
FAD  A 512 (-4.0A)
None
None
 1.25A 3n62A-4jq9A:
undetectable		 3n62A-4jq9A:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3V_A_TOPA193_1
(DIHYDROFOLATE
REDUCTASE)		 4jq9 DIHYDROLIPOYL
DEHYDROGENASE
(Escherichia
coli) 		4 / 5 ASP A 208
LEU A 234
ILE A 211
PRO A 212
 None
 1.17A 3s3vA-4jq9A:
undetectable		 3s3vA-4jq9A:
15.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5L_A_UEGA300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 4jq9 DIHYDROLIPOYL
DEHYDROGENASE
(Escherichia
coli) 		5 / 11 GLY A  18
ALA A 331
GLY A 328
VAL A  11
CYH A  25
 None
 1.28A 4c5lA-4jq9A:
3.5		 4c5lA-4jq9A:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5L_D_UEGD300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 4jq9 DIHYDROLIPOYL
DEHYDROGENASE
(Escherichia
coli) 		5 / 10 GLY A  18
ALA A 331
GLY A 328
VAL A  11
CYH A  25
 None
 1.26A 4c5lD-4jq9A:
undetectable		 4c5lD-4jq9A:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5N_D_UEGD300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 4jq9 DIHYDROLIPOYL
DEHYDROGENASE
(Escherichia
coli) 		5 / 10 GLY A  18
ALA A 331
GLY A 328
VAL A  11
CYH A  25
 None
 1.24A 4c5nD-4jq9A:
undetectable		 4c5nD-4jq9A:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DCM_A_SAMA401_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE G)		 4jq9 DIHYDROLIPOYL
DEHYDROGENASE
(Escherichia
coli) 		5 / 11 GLY A 312
GLY A 146
ILE A 143
ASP A 313
PRO A  16
 FAD  A 512 (-3.4A)
FAD  A 512 (-3.4A)
None
FAD  A 512 (-3.0A)
FAD  A 512 (-3.9A)
 1.14A 4dcmA-4jq9A:
3.7		 4dcmA-4jq9A:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DT8_B_ADNB401_1
(APH(2'')-ID)		 4jq9 DIHYDROLIPOYL
DEHYDROGENASE
(Escherichia
coli) 		5 / 10 GLY A  18
ALA A  17
ILE A 311
ILE A 295
ILE A 314
 None
FAD  A 512 (-3.4A)
None
None
None
 1.05A 4dt8B-4jq9A:
undetectable		 4dt8B-4jq9A:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ENH_A_FVXA602_1
(CHOLESTEROL
24-HYDROXYLASE)		 4jq9 DIHYDROLIPOYL
DEHYDROGENASE
(Escherichia
coli) 		5 / 12 LEU A 422
ILE A 413
ILE A 350
ALA A 351
ALA A 214
 None
 1.06A 4enhA-4jq9A:
undetectable		 4enhA-4jq9A:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IK7_A_IMNA201_1
(TRANSTHYRETIN)		 4jq9 DIHYDROLIPOYL
DEHYDROGENASE
(Escherichia
coli) 		4 / 7 MET A 396
LYS A 398
ALA A 412
VAL A 357
 None
 0.93A 4ik7A-4jq9A:
undetectable		 4ik7A-4jq9A:
15.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJV_A_RITA500_1
(PROTEASE)		 4jq9 DIHYDROLIPOYL
DEHYDROGENASE
(Escherichia
coli) 		5 / 12 GLY A  15
ALA A  14
VAL A 112
THR A  32
ILE A  34
 FAD  A 512 (-3.4A)
None
None
None
None
 0.88A 4njvA-4jq9A:
undetectable		 4njvA-4jq9A:
12.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O5F_A_PAUA301_0
(TYPE III
PANTOTHENATE KINASE)		 4jq9 DIHYDROLIPOYL
DEHYDROGENASE
(Escherichia
coli) 		5 / 12 LEU A 454
GLY A 453
THR A 447
LEU A 421
THR A 397
 None
 1.13A 4o5fA-4jq9A:
undetectable
4o5fB-4jq9A:
undetectable		 4o5fA-4jq9A:
21.81
4o5fB-4jq9A:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O5F_B_PAUB302_0
(TYPE III
PANTOTHENATE KINASE)		 4jq9 DIHYDROLIPOYL
DEHYDROGENASE
(Escherichia
coli) 		5 / 12 LEU A 421
THR A 397
LEU A 454
GLY A 453
THR A 447
 None
 1.11A 4o5fA-4jq9A:
undetectable
4o5fB-4jq9A:
undetectable		 4o5fA-4jq9A:
21.81
4o5fB-4jq9A:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QGI_A_ROCA101_2
(PROTEASE)		 4jq9 DIHYDROLIPOYL
DEHYDROGENASE
(Escherichia
coli) 		5 / 11 ALA A 428
VAL A 452
GLY A 410
ILE A 409
ILE A 438
 None
 0.94A 4qgiB-4jq9A:
undetectable		 4qgiB-4jq9A:
11.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_A_SAMA301_0
(UNCHARACTERIZED
PROTEIN)		 4jq9 DIHYDROLIPOYL
DEHYDROGENASE
(Escherichia
coli) 		5 / 12 ARG A 296
GLY A 316
GLN A 317
GLY A 293
PHE A 294
 SO4  A 511 (-2.2A)
SO4  A 511 (-3.0A)
SO4  A 511 (-4.0A)
None
SO4  A 511 (-3.5A)
 1.11A 4r29A-4jq9A:
undetectable		 4r29A-4jq9A:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_D_SAMD301_0
(UNCHARACTERIZED
PROTEIN)		 4jq9 DIHYDROLIPOYL
DEHYDROGENASE
(Escherichia
coli) 		5 / 12 ARG A 296
GLY A 316
GLN A 317
GLY A 293
PHE A 294
 SO4  A 511 (-2.2A)
SO4  A 511 (-3.0A)
SO4  A 511 (-4.0A)
None
SO4  A 511 (-3.5A)
 1.11A 4r29D-4jq9A:
undetectable		 4r29D-4jq9A:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z2D_F_LFXF102_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
SYMMETRIZED E-SITE
DNA)		 4jq9 DIHYDROLIPOYL
DEHYDROGENASE
(Escherichia
coli) 		3 / 4 ARG A  37
GLY A 115
GLU A  36
 FAD  A 512 (-3.7A)
None
FAD  A 512 (-2.6A)
 0.54A 4z2dB-4jq9A:
undetectable
4z2dC-4jq9A:
undetectable		 4z2dB-4jq9A:
23.82
4z2dC-4jq9A:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B8H_A_PAUA302_0
(TYPE III
PANTOTHENATE KINASE)		 4jq9 DIHYDROLIPOYL
DEHYDROGENASE
(Escherichia
coli) 		5 / 12 LEU A 454
GLY A 453
THR A 447
LEU A 421
THR A 397
 None
 1.08A 5b8hA-4jq9A:
undetectable
5b8hB-4jq9A:
undetectable		 5b8hA-4jq9A:
21.31
5b8hB-4jq9A:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B8H_B_PAUB302_0
(TYPE III
PANTOTHENATE KINASE)		 4jq9 DIHYDROLIPOYL
DEHYDROGENASE
(Escherichia
coli) 		5 / 12 LEU A 421
THR A 397
LEU A 454
GLY A 453
THR A 447
 None
 1.10A 5b8hA-4jq9A:
undetectable
5b8hB-4jq9A:
undetectable		 5b8hA-4jq9A:
21.31
5b8hB-4jq9A:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_A_PAUA602_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)		 4jq9 DIHYDROLIPOYL
DEHYDROGENASE
(Escherichia
coli) 		4 / 7 GLY A 324
SER A  20
GLY A  18
ALA A 321
 None
None
None
FAD  A 512 (-3.4A)
 0.97A 5e26A-4jq9A:
undetectable
5e26B-4jq9A:
undetectable		 5e26A-4jq9A:
22.08
5e26B-4jq9A:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQX_A_ROCA101_1
(PROTEASE E35D-SQV)		 4jq9 DIHYDROLIPOYL
DEHYDROGENASE
(Escherichia
coli) 		6 / 12 GLY A 411
ALA A 412
GLY A 419
ILE A 350
VAL A 219
ILE A 218
 None
 1.21A 5kqxA-4jq9A:
undetectable		 5kqxA-4jq9A:
13.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_H_BO2H306_1
(PROTEASOME SUBUNIT
BETA TYPE-7
PROTEASOME SUBUNIT
BETA TYPE-3)		 4jq9 DIHYDROLIPOYL
DEHYDROGENASE
(Escherichia
coli) 		5 / 10 ALA A  21
GLU A 327
ALA A  14
GLY A  15
ALA A 144
 None
None
None
FAD  A 512 (-3.4A)
FAD  A 512 (-4.8A)
 1.17A 5lf3H-4jq9A:
2.2
5lf3I-4jq9A:
undetectable		 5lf3H-4jq9A:
20.43
5lf3I-4jq9A:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_V_BO2V303_1
(PROTEASOME SUBUNIT
BETA TYPE-7
PROTEASOME SUBUNIT
BETA TYPE-3)		 4jq9 DIHYDROLIPOYL
DEHYDROGENASE
(Escherichia
coli) 		5 / 10 ALA A  21
GLU A 327
ALA A  14
GLY A  15
ALA A 144
 None
None
None
FAD  A 512 (-3.4A)
FAD  A 512 (-4.8A)
 1.19A 5lf3V-4jq9A:
2.3
5lf3W-4jq9A:
undetectable		 5lf3V-4jq9A:
20.43
5lf3W-4jq9A:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_A_ACRA1431_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 4jq9 DIHYDROLIPOYL
DEHYDROGENASE
(Escherichia
coli) 		4 / 7 ASN A 123
HIS A 307
ASP A 139
ASN A 140
 SO4  A 502 (-4.9A)
None
None
None
 1.07A 5x7pA-4jq9A:
undetectable		 5x7pA-4jq9A:
18.20