SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4jqr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WU8_C_ADNC502_1
(HYPOTHETICAL PROTEIN
PH0463)		 4jqr HYPOTHETICAL PROTEIN
(Bacteroides
caccae) 		4 / 7 PHE A  60
ASN A  68
ASN A  65
VAL A  31
 None
EDO  A 304 (-3.8A)
None
EDO  A 310 (-4.5A)
 1.41A 1wu8A-4jqrA:
undetectable
1wu8C-4jqrA:
undetectable		 1wu8A-4jqrA:
23.11
1wu8C-4jqrA:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OWX_A_XRAA233_2
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 4jqr HYPOTHETICAL PROTEIN
(Bacteroides
caccae) 		4 / 5 VAL A  30
PHE A  33
ILE A 113
PHE A  60
 None
None
EDO  A 310 (-4.2A)
None
 1.12A 3owxB-4jqrA:
undetectable		 3owxB-4jqrA:
24.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PEO_F_CU9F301_2
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 4jqr HYPOTHETICAL PROTEIN
(Bacteroides
caccae) 		4 / 6 GLN A  56
TYR A  73
GLN A  43
ILE A  45
 None
None
EDO  A 313 (-3.0A)
None
 1.04A 3peoG-4jqrA:
undetectable		 3peoG-4jqrA:
24.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EB6_C_VLBC503_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA CHAIN)		 4jqr HYPOTHETICAL PROTEIN
(Bacteroides
caccae) 		5 / 12 VAL A 115
PRO A 221
ASN A 144
ILE A 102
ILE A 204
 None
 1.28A 4eb6B-4jqrA:
undetectable
4eb6C-4jqrA:
undetectable		 4eb6B-4jqrA:
19.05
4eb6C-4jqrA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O4D_A_ACTA406_0
(INOSITOL
HEXAKISPHOSPHATE
KINASE)		 4jqr HYPOTHETICAL PROTEIN
(Bacteroides
caccae) 		4 / 7 ASP A 116
THR A 124
PHE A  82
SER A  81
 EDO  A 315 ( 4.9A)
EDO  A 311 ( 4.8A)
None
EDO  A 314 ( 3.7A)
 1.46A 4o4dA-4jqrA:
undetectable		 4o4dA-4jqrA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B89_A_NOVA403_1
(LIPOPOLYSACCHARIDE
EXPORT SYSTEM
ATP-BINDING PROTEIN
LPTB)		 4jqr HYPOTHETICAL PROTEIN
(Bacteroides
caccae) 		5 / 10 ALA A 185
PRO A 221
SER A 117
PHE A  85
VAL A 217
 None
 1.40A 6b89A-4jqrA:
undetectable		 6b89A-4jqrA:
16.37